Mutation in SLC7A14 gene causes autosomal recessive retinitis pigmentosa (arRP). Here we describe the generation and characterization of human induced pluripotent stem cell (hiPSC) lines of RP patient with SLC7A14 mutation and his healthy parents. hiPSCs were derived from peripheral blood mononuclear cells (PBMCs) reprogrammed with integration-free plasmids including the reprogramming factors OCT3/4, SOX2, MYC and KLF4. All the established hiPSC lines showed normal karyotype, pluripotency and differentiation capacity.
基金：
National Key R&D Program of China [2017YFA0105300]
第一作者机构：[1]Wenzhou Med Univ, Div Ophthalm Genet, Inst Stem Cell Res, Eye Hosp,Lab Stem Cell & Retinal Regenerat, Wenzhou 325027, Peoples R China
共同第一作者：
通讯作者：
通讯机构：[2]Capital Med Univ, Beijing Inst Ophthalmol, Beijing Tongren Eye Ctr, Beijing Tongren Hosp,Beijing Ophthalmol & Visual, Beijing 100730, Peoples R China[*1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing 100730, China
推荐引用方式(GB/T 7714)：
Li Yan-Ping,Liu Hui,Jin Zi-Bing.Generation of three human iPSC lines from a retinitis pigmentosa family with SLC7A14 mutation[J].STEM CELL RESEARCH.2020,49:doi:10.1016/j.scr.2020.102075.
APA：
Li, Yan-Ping,Liu, Hui&Jin, Zi-Bing.(2020).Generation of three human iPSC lines from a retinitis pigmentosa family with SLC7A14 mutation.STEM CELL RESEARCH,49,
MLA：
Li, Yan-Ping,et al."Generation of three human iPSC lines from a retinitis pigmentosa family with SLC7A14 mutation".STEM CELL RESEARCH 49.(2020)
