机构:[1]Chinese Acad Med Sci & Peking Union Med Coll, Plast Surg Hosp, Beijing, Peoples R China[2]Capital Med Univ, Beijing Tongren Hosp, Dept Orthoped, Beijing, Peoples R China临床科室骨科首都医科大学附属北京同仁医院首都医科大学附属同仁医院
With the continuous development of bone tissue engineering, the importance of immune response in bone tissue regeneration is gradually recognized. The new bone tissue engineering products should possess immunoregulatory functions, harmonizing the interactions between the bone's immune defense and regeneration systems, and promoting tissue regeneration. This article will interpret the relationship between the bone immune system, bone tissue regeneration, as well as the immunoregulatory function of bone biomaterials and seed stem cells in bone tissue engineering. This review locates arears for foucusing efforts at providing novel designs ideas about the development of immune-mediation targeted bone tissue engineering products and the evaluation strategy for the osteoimmunomodulation property of bone biomaterials. (C) 2021, The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V.
基金:
Special Research Fund for Central Universities, Peking Union Medical College of China [3332020094]; Research Fund of Beijing Tongren Hospital, Capital Medical University of China [2020-YJJ-ZZL-040]
第一作者机构:[1]Chinese Acad Med Sci & Peking Union Med Coll, Plast Surg Hosp, Beijing, Peoples R China
通讯作者:
通讯机构:[2]Capital Med Univ, Beijing Tongren Hosp, Dept Orthoped, Beijing, Peoples R China[*1]No.1 of Dongjiaominxiang Street, Dongcheng District, Beijing, 100730, China.
推荐引用方式(GB/T 7714):
Ouyang Long,Cao Jiankun,Dai Qiang,et al.New insight of immuno-engineering in osteoimmunomodulation for bone regeneration[J].REGENERATIVE THERAPY.2021,18:24-29.doi:10.1016/j.reth.2021.03.003.
APA:
Ouyang, Long,Cao, Jiankun,Dai, Qiang&Qiu, Daojing.(2021).New insight of immuno-engineering in osteoimmunomodulation for bone regeneration.REGENERATIVE THERAPY,18,
MLA:
Ouyang, Long,et al."New insight of immuno-engineering in osteoimmunomodulation for bone regeneration".REGENERATIVE THERAPY 18.(2021):24-29