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A Multicenter Study of the Prevalence of Dry Eye Disease in Chinese Refractive Surgery Candidates

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收录情况： ◇ SCIE

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机构： [a]Department of Ophthalmology and Optometry, EENT Hospital, Fudan University, Shanghai, China [b]NHC KeyLaboratory of Myopia (Fudan University), Shanghai, China [c]Shanghai Research Center of Ophthalmology andOptometry, Shanghai, China [d]Shanxi Center Hospital The Chinese Army Police Force, Taiyuan, China [e]PekingUnion Medical College Hospital, Beijing, China [f]Sichuan Provincial People’s Hospital, Chengdu, China [g]ZhongshanOphthalmic Center, Sun Yat-sun University, Guangzhou, China [h]The First Affiliated Hospital of Harbin MedicalUniversity, Harbin, China [i]Shanghai Xinshijie Eye Hospital, Shanghai, China [j]Aier Eye Hospital (Changsha),Changsha, China [k]Beijing Tongren Hospital, Capital Medical University, Beijing, China [l]Weifang Eye Hospital,Weifang, China [m]Lixiang Eye Hospital of Soochow University, Suzhou, China [n]Aier Eye Hospital (Shenyang),Shenyang, China [o]Chongqing Daping Hospital, Chongqing, China [p]Wayne State University School of Medicine,Detroit, MI, USA

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关键词： Contact lens Dry eye Keratorefractive surgery Schirmer test Tear film breakup time

摘要：

Objective: The aim of this study was to determine the prevalence of preoperative dry eye disease and evaluate tear film function in refractive surgery candidates in China. Methods: In this prospective noninterventional cross-sectional study, refractive surgical candidates from 13 preselected eye hospitals in China were recruited from July 2015 to February 2016. Patient histories, subjective symptoms, tear film breakup time (TBUT), ocular surface fluorescein staining, and Schirmer I tests (SIT), were assessed to conduct subgroup analysis. Results: A total of 1,849 patients were recruited, 41.4% were diagnosed with dry eye disease (766/1,849) and 44.9% (830/1,849) of subjects had a positive history of contact lens (CL) wear. The overall mean TBUT and SIT values were 7.3 ± 3.7 s and 15.2 ± 8.8 mm, respectively. The total prevalence of ocular surface fluorescein staining was 23.46% (422/1,849); 44.62% of patients had TBUT <5 s and 23.20% of patients had SIT <5 mm. CL wearers were observed to have a higher prevalence of dry eye than non-CL wearers (54.1 vs. 35.2%, OR = 2.17, 95% CI: 1.77-2.65). Conclusions: In this study, the most common abnormal finding in dry eye disease was tear film instability. A high proportion of refractive surgery candidates have preexisting dry eye disease and a history of CL wear prior to surgery. Careful attention should be given to the evaluation of preoperative dry eye in refractive surgery candidates. © 2020 S. Karger AG, Basel. Copyright: All rights reserved.

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出版当年[2020]版：

大类 | 4 区医学

小类 | 4 区眼科学

最新[2023]版：

大类 | 4 区医学

小类 | 3 区眼科学

JCR分区：

出版当年[2019]版：

Q3 OPHTHALMOLOGY

最新[2023]版：

Q2 OPHTHALMOLOGY

影响因子： 2 最新[2023版] 2.1 最新五年平均 1.961 出版当年[2019版] 1.908 出版当年五年平均 1.685 出版前一年[2018版] 2.892 出版后一年[2020版]

第一作者：

第一作者机构： [a]Department of Ophthalmology and Optometry, EENT Hospital, Fudan University, Shanghai, China [b]NHC KeyLaboratory of Myopia (Fudan University), Shanghai, China [c]Shanghai Research Center of Ophthalmology andOptometry, Shanghai, China

共同第一作者：

通讯作者：

通讯机构： [a]Department of Ophthalmology and Optometry, EENT Hospital, Fudan University, Shanghai, China [b]NHC KeyLaboratory of Myopia (Fudan University), Shanghai, China [c]Shanghai Research Center of Ophthalmology andOptometry, Shanghai, China [*a]Department of Ophthalmology and Optometry Myopia Key Laboratory of the Health Ministry, Shanghai Research Center of Ophthalmology and Optometry, Eye and ENT Hospital of Fudan University No. 83 Fenyang Road, Shanghai 200031 (China)

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A Multicenter Study of the Prevalence of Dry Eye Disease in Chinese Refractive Surgery Candidates

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