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Automatic glaucoma detection based on transfer induced attention network.

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收录情况: ◇ SCIE ◇ EI

机构: [1]Faculty of Information Technology, Beijing University of Technology, Beijing, China [2]Beijing Tongren Hospital, CapitalMedical University, Beijing, China [3]Beijing Children’s Hospital, Capital Medical University, Beijing, China
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摘要:
Glaucoma is one of the causes that leads to irreversible vision loss. Automatic glaucoma detection based on fundus images has been widely studied in recent years. However, existing methods mainly depend on a considerable amount of labeled data to train the model, which is a serious constraint for real-world glaucoma detection. In this paper, we introduce a transfer learning technique that leverages the fundus feature learned from similar ophthalmic data to facilitate diagnosing glaucoma. Specifically, a Transfer Induced Attention Network (TIA-Net) for automatic glaucoma detection is proposed, which extracts the discriminative features that fully characterize the glaucoma-related deep patterns under limited supervision. By integrating the channel-wise attention and maximum mean discrepancy, our proposed method can achieve a smooth transition between general and specific features, thus enhancing the feature transferability. To delimit the boundary between general and specific features precisely, we first investigate how many layers should be transferred during training with the source dataset network. Next, we compare our proposed model to previously mentioned methods and analyze their performance. Finally, with the advantages of the model design, we provide a transparent and interpretable transferring visualization by highlighting the key specific features in each fundus image. We evaluate the effectiveness of TIA-Net on two real clinical datasets and achieve an accuracy of 85.7%/76.6%, sensitivity of 84.9%/75.3%, specificity of 86.9%/77.2%, and AUC of 0.929 and 0.835, far better than other state-of-the-art methods. Different from previous studies applied classic CNN models to transfer features from the non-medical dataset, we leverage knowledge from the similar ophthalmic dataset and propose an attention-based deep transfer learning model for the glaucoma diagnosis task. Extensive experiments on two real clinical datasets show that our TIA-Net outperforms other state-of-the-art methods, and meanwhile, it has certain medical value and significance for the early diagnosis of other medical tasks.

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出版当年[2020]版:
大类 | 4 区 医学
小类 | 4 区 工程:生物医学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 工程:生物医学
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出版当年[2019]版:
Q3 ENGINEERING, BIOMEDICAL
最新[2023]版:
Q3 ENGINEERING, BIOMEDICAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2019版] 出版当年五年平均 出版前一年[2018版] 出版后一年[2020版]

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第一作者机构: [1]Faculty of Information Technology, Beijing University of Technology, Beijing, China
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