机构:[1]Capital Med Univ, Beijing Tongren Hosp, Dept Endocrinol, 1 Dongjiaomin Xiang, Beijing 100730, Peoples R China首都医科大学附属北京同仁医院临床科室内分泌科[2]Capital Med Univ, Beijing Ditan Hosp, Dept Med Records & Stat, Beijing, Peoples R China[3]Jinsong Community Hlth Serv Ctr, Beijing, Peoples R China[4]Xinjiekou Community Hlth Serv Ctr, Beijing, Peoples R China[5]Cuigezhuang Community Hlth Serv Ctr, Beijing, Peoples R China[6]Capital Med Univ, Fuxing Hosp, Yuetan Community Hlth Serv Ctr, Beijing, Peoples R China[7]Aerosp Cent Hosp, Beijing, Peoples R China[8]Sanlitun Community Hlth Serv Ctr, Beijing, Peoples R China[9]Beijing Aerosp Gen Hosp, Dept Endocrinol, Beijing, Peoples R China[10]Jiangtai Community Hlth Serv Ctr, Beijing, Peoples R China[11]Majiapu Community Hlth Serv Ctr, Beijing, Peoples R China[12]Zuojiazhuang Community Hlth Serv Ctr, Beijing, Peoples R China[13]Balizhuang Community Hlth Serv Ctr, Beijing, Peoples R China[14]First Peoples Hosp Dongcheng Dist, Beijing, Peoples R China[15]Dongfeng Community Hlth Serv Ctr, Beijing, Peoples R China[16]Sijiqing Community Hlth Serv Ctr, Beijing, Peoples R China[17]Univ Oxford, Radcliffe Dept Med, Diabet Trials Unit, Oxford, England
Obesity increases the risk of developing cardiovascular disease and other metabolic diseases. We intended to compare three different anthropometric indicators of obesity, in predicting the incidence of cardiovascular events in Chinese type 2 diabetes. Beijing Community Diabetes Study was a prospective multi-center study conducted in Beijing community health centers. Type 2 diabetes patients from fourteen community health centers were enrolled at baseline. The primary endpoint was cardiovascular events. The upper quartile of neck circumference (NC) was set as greater NC. A total of 3299 diabetes patients were enrolled. In which, 941 (28.52%) had cardiovascular disease at baseline. Logistic analysis showed that central obesity (waist circumference (WC) above 90 cm in men and 85 cm in women) and greater NC were all related to baseline cardiovascular disease (adjusted OR=1.49, and 1.55). After 10-year follow-up, 340 (10.31%) had cardiovascular events. Compared with patients without cardiovascular events, those having cardiovascular events had higher BMI, larger WC and NC. Cox regression analysis showed that greater WC and NC were all associated with the occurrence of cardiovascular events (adjusted HR=1.41, and 1.38). A higher NC and WC might increase the risk of cardiovascular events by about 40% in type 2 diabetes patients in Beijing communities.
基金:
Capital’s Funds for Health Improvement
and Research (2016-1-2057, 2016-2-2054, 2020-1-1181), Beijing Municipal Science &Technology Commission
(Z151100004015021) and the Beijing Municipal Training Foundation for Highly-qualified and Technological
Talents of Health System (2014-3-013).
第一作者机构:[1]Capital Med Univ, Beijing Tongren Hosp, Dept Endocrinol, 1 Dongjiaomin Xiang, Beijing 100730, Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Yang Guang-Ran,Yuan Ming-Xia,Wan Gang,et al.Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23)[J].SCIENTIFIC REPORTS.2021,11(1):doi:10.1038/s41598-021-88927-9.
APA:
Yang, Guang-Ran,Yuan, Ming-Xia,Wan, Gang,Zhang, Xue-Lian,Fu, Han-Jing...&Holman, Rury R..(2021).Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23).SCIENTIFIC REPORTS,11,(1)
MLA:
Yang, Guang-Ran,et al."Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23)".SCIENTIFIC REPORTS 11..1(2021)