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Ganglion Cell Complex Parameters in Primary Angle Closure Suspects.

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收录情况： ◇ SCIE

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机构： [1]Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China [2]NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China [3]Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China [4]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, China. [5]Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China. [6]Department of Ophthalmology, The Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, Sichuan, China. [7]Department of Ophthalmology, First People's Hospital of Yunnan Province，Kunming, Yunnan, China. [8]Department of Ophthalmology, Beijing Friendship Hospital, Capital Medical University, Beijing, China. [9]Ophthalmology, University of California San Francisco, San Francisco, California, USA.

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This study aimed to investigate the ganglion cell complex (GCC) parameters in primary angle closure suspects (PACS) and identify the related factors.A total of 731 subjects, including 289 subjects with PACS and 442 subjects without PACS, underwent RTVue XR OCT. GCC parameters were compared between the two groups. The linear mixed-effects model was performed to evaluate the relationships between the GCC parameters and related factors.Significant differences were found in gender, age, spherical refractive error, height, waist, anterior chamber depth, lens thickness, axial length, superior GCC thickness, ganglion cell complex focal loss volume, ganglion cell complex global loss volume, and ganglion cell complex root mean square between PACS and normal controls. The linear mixed-effects model showed that age (p = 0.008) and blood glucose (p = 0.001) were negatively correlated with average GCC thickness in PACS subjects, and PACS (p = 0.036) and age (p < 0.001) were the key influencing factors for average GCC thickness.GCC parameters in PACS subjects are different from those in normal controls. Careful explanation should be considered when evaluating changes of GCC parameters in patients with PACD.© 2021 The Author(s) Published by S. Karger AG, Basel.

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出版当年[2020]版：

大类 | 4 区医学

小类 | 4 区眼科学

最新[2023]版：

大类 | 4 区医学

小类 | 3 区眼科学

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出版当年[2019]版：

Q3 OPHTHALMOLOGY

最新[2023]版：

Q2 OPHTHALMOLOGY

影响因子： 2 最新[2023版] 2.1 最新五年平均 1.961 出版当年[2019版] 1.908 出版当年五年平均 1.685 出版前一年[2018版] 2.892 出版后一年[2020版]

第一作者：

第一作者机构： [1]Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China [2]NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China [3]Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China

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通讯作者：

通讯机构： [4]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, China. [*1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key LaboratoryNo.1 Dongjiaominxiang, Dongcheng District, 100730, Beijing, China

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