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A Clinical Trial of IntensiVE Dialysis

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研究单位： [1]The George Institute [2]National Health and Medical Research Council, Australia [3]Baxter Healthcare Corporation [4]The Canberra Hospital,Canberra,Australian Capital Territory,Australia [5]RPAH/Concord,Sydney,New South Wales,Australia,2050 [6]Auckland City Hospital,Auckland,New Zealand [7]Sydney Adventist Hospital,Sydney,New South Wales,Australia,2076 [8]Liverpool Hospital,Sydney,New South Wales,Australia [9]Sydney Dialysis Centre,Sydney,New South Wales,Australia [10]Princess Alexandra Hospital,Brisbane,Queensland,Australia [11]Royal Brisbane Hospital,Brisbane,Queensland,Australia [12]Gold Coast Hospital,Gold Coast,Queensland,Australia [13]Nambour General Hospital,Nambour,Queensland,Australia [14]Royal Hobart Hospital,Hobart,Tasmania,Australia [15]Austin Hospital,Melbourne,Victoria,Australia [16]Monash Medical Centre,Melbourne,Victoria,Australia [17]Royal Melbourne Hospital,Melbourne,Victoria,Australia [18]Sir Charles Gairdner Hospital,Perth,Western Australia,Australia [19]UBC,Vancouver,British Columbia,Canada [20]St Michael's Hospital,Toronto,Ontario,Canada,M5B 1W8 [21]University Health Network,Toronto,Ontario,Canada [22]Beijing Hospital of Traditional Chinese Medicine,Beijing,China [23]Beijing Tongren Hospital,Beijing,China [24]Civil Aviation General Hospital,Chaoyang District,,Beijing,China [25]China-Japan Friendship Hospital,Chaoyang District,Beijing,China [26]First Affiliated Hospital of Chinese PLA General Hospital,Haidian District,Beijing,China [27]Beijing Hospital,Xicheng District,Beijing,China [28]Peking University First Hospital,Xicheng District,Beijing,China [29]Peking University People's Hospital,Xicheng District,Beijing,China [30]Shenzhen Hospital of Peking University,Shenzhen,Guangdong,China [31]Fourth Hospital Affiliated to Hebei Medical University,Shijiazhuang,Hebei,China [32]Shijiazhuang First People's Hospital,Shijiazhuang,Hebei,China [33]Third Hospital Affiliated to Hebei Medical University,Shijiazhuang,Hebei,China [34]Zhengzhou University affiliated first hospital,Zhengzhou,Henan,China [35]First Affiliated Hospital of Inner Mongolia, Baotou Medical College,Baotou,Inner Mongolia,China [36]Zhongda Hospital, Southeast University,Nanjing,Jiangsu,China [37]Fourth Hospital Affiliated to Jilin University (FAW General Hospital),Changchun,Jilin,China [38]Dalian Medical affiliated first hospital,Dalian,Liaoning,China [39]Shanghai Ruijin Hospital,Shanghai,Shanghai,China [40]The Chinese PLA Shanghai 85th Hospital,Shanghai,Shanghai,China [41]The second affiliated hospital of Shanxi Medical University,Taiyuan City,Shanxi,China [42]Huaxi Hospital of Sichuan University,Chengdu,Sichuan,China [43]North Shore Hospital,Auckland,New Zealand

关键词： Randomized Controlled Trial Clinical Trial Controlled Clinical Trial Phase IV Multicenter Study End Stage Kidney Disease Hemodialysis Renal Dialysis Renal Replacement Therapy Nocturnal Dialysis Extended dialysis Quality of Life Quality Adjusted Life Year Hypertrophy Left Ventricular Blood Pressure Hypertension Anemia Hematinics Erythropoiesis Stimulating Agents Cost-utility Analysis Economic Evaluation Health Care Utilisation Health Care Costs Health Expenditures Hospitalization Cost Analysis Cardiovascular Diseases Acute Coronary Syndrome Myocardial Infarction Stroke Cerebrovascular Disorders Mortality Arteriovenous Fistula Arteriovenous Shunt Surgical Thrombosis Infection

研究目的：

This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.