研究单位:[1]Quark Pharmaceuticals[2]University of Arkansas Medical Center, Jones Eye Institute,Little Rock,Arkansas,United States,72205[3]Loma Linda University Eye Institute,Loma Linda,California,United States,92354[4]University of Southern California,Los Angeles,California,United States,90033[5]NeuroEyeOrbit Institute,Los Angeles,California,United States,90048[6]Stanford University,Palo Alto,California,United States,94303[7]Unversity of California, Los Angeles (UCLA),Pasadena,California,United States,91105[8]Tan Tock Seng Hospital, Department of Ophthalmology,Singapore,Singapore,308433[9]University of Colorado Denver, Department of Neurology,Aurora,Colorado,United States,80045[10]Retina Consultants of Southern Colorado, PC,Colorado Springs,Colorado,United States,80909[11]The Eye Care Group,Waterbury,Connecticut,United States,06708[12]Cape Coral Eye Center,Cape Coral,Florida,United States,33904[13]University of Miami Miller School of Medicine/Bascom Palmer Eye Institute,Miami,Florida,United States,33136[14]Sarasota Retina Institute,Sarasota,Florida,United States,34239[15]Northwestern University,Chicago,Illinois,United States,60611[16]University of Illinois at Chicago, Department of Ophthalmology (MC 648),Chicago,Illinois,United States,60612[17]NorthShore University Healthsystem,Glenview,Illinois,United States,60026[18]University of Kentucky, Department of Neurology,Lexington,Kentucky,United States,40536[19]Greater Baltimore Medical Center,Baltimore,Maryland,United States,21204[20]Bethesda Neurology, LLC,Bethesda,Maryland,United States,20852[21]Massachusetts Eye and Ear Infirmary,Boston,Massachusetts,United States,02114[22]Boston Medical Center,Boston,Massachusetts,United States,21118[23]University of Michigan,Ann Arbor,Michigan,United States,48105[24]University of Minnesota,Minneapolis,Minnesota,United States,55455[25]Mayo Clinic,Rochester,Minnesota,United States,55905[26]Washington University in St. Louis,Saint Louis,Missouri,United States,63110[27]University of Nebraska Medical Center and Truhlsen Eye Institute,Omaha,Nebraska,United States,68198[28]Rutgers, New Jersey Medical School,Newark,New Jersey,United States,07103[29]New York Eye and Ear Infirmary of Mount Sinai,New York,New York,United States,10003[30]Cornell University School of Medicine,New York,New York,United States,10583[31]University of Rochester, Flaum Eye Institute,Rochester,New York,United States,14642[32]State University of New York at Stony Brook,Stony Brook,New York,United States,11794[33]SUNY Upstate Medical University,Syracuse,New York,United States,13210[34]Duke University Eye Center,Durham,North Carolina,United States,27705[35]Raleigh Neurology Associates,Raleigh,North Carolina,United States,27607[36]Cleveland Clinic, Cole Eye Institute,Cleveland,Ohio,United States,44195[37]Dean McGee Eye Institute,Oklahoma City,Oklahoma,United States,73013[38]University of Pennsylvania, Scheie Eye Institute,Philadelphia,Pennsylvania,United States,19104[39]Retina Consultants of Charleston,Charleston,South Carolina,United States,29414[40]University of Houston, Neuro-Ophth of Texas,Houston,Texas,United States,77025[41]Houston Methodist Hospital, Blanton Eye Institute,Houston,Texas,United States,77030[42]Foresight Studies,San Antonio,Texas,United States,78240[43]University of Utah John A. Moran Eye Center,Salt Lake City,Utah,United States,84132[44]University of Virginia Health Sciences Center,Charlottesville,Virginia,United States,22908[45]Swedish Medical Center, CO/NOCNW,Seattle,Washington,United States,98104[46]University of Washington Department of Ophthalmology,Seattle,Washington,United States,98104[47]Sydney Eye Hospital/Save Sight Institute,Sydney,New South Wales,Australia,2000[48]Vision South Australia,Kent Town,South Australia,Australia,5267[49]The Royal Victorian Eye and Ear Hospital,Fitzroy,Victoria,Australia,3002[50]Royal Perth Hospital,Perth,Western Australia,Australia,6000[51]The Second Xiangya Hospital of Central South University,Changsha,Hunan,China,410013[52]Peking University Eye Center, The Third Hospital Peking University.,Beijing,China,100191[53]Beijing Tongren Hospital, Capital Medical University,Beijing,China,100730[54]Peking Union Medical College Hospital,Beijing,China,100730[55]Tianjin Eye Hospital,Tianjin,China,300000[56]Universitätsmedizin d. Johannes Gutenberg-Universität Mainz,Mainz,Rheinland-Pfalz,Germany,55131[57]Universitätsklinikum Aachen-Augenklinik,Aachen,Germany,52074[58]Universitätsklinikum Carl Gustav Carus-Dresden-Klinik und Poliklinik für Augenheilkunde,Dresden,Germany,01307[59]Universitätsklinikum Münster,Münster,Germany,48149[60]Universitätsklinikum Regensburg-Klinik und Poliklinik für Augenheilkunde,Regensburg,Germany,93053[61]Universitäts-Augenklinik Tübingen,Tubingen,Germany,72076[62]L V Prasad Eye Institute,Hyderabad,Andhra Pradesh,India,500034[63]L V Prasad Eye Institute,Visakhapatnam,Andhra Pradesh,India,530040[64]Sri Sankaradeva Nethralaya,Guwahati,Assam,India,781028[65]Narayana Nethralaya,Bangalore,Karnataka,,India,560010[66]PBMA'S H. V. Desai Eye Hospital,Pune,Maharashtra,India,411060[67]L V Prasad Eye Institute,Bhubaneswar,Orissa,India,751024[68]Sankara Nethralaya (Vision Research Foundation),Chennai,Tami Nadu,India,600006[69]Aravind Eye Hospital,Madurai,Tamil Nadu,India,625020[70]Sanjay Gandhi Postgraduate Institute of Medical Sciences,Lucknow,Uttar Pradesh,India,226014[71]ICARE Research Centre and Post Graduate Institute,Noida,Uttar Pradesh,India,201301[72]Dr. Rajendra Prasad Centre for Ophthalmic Sciences, A.I.I.M.S.,New Delhi,India,110029[73]Datta Meghe Institute of Medical Sciences,Wardha,India,442005[74]Hadassah Medical Center,Jerusalem,Yerushalayim,Israel,9112001[75]Soroka University Medical Center,Beer-Sheva,Israel,84101[76]Bnai Zion Medical Center,Haifa,Israel,31048[77]Rabin Medical Center, Belinson Campus,Petach-Tikva,Israel,49100[78]Kaplan Medical Center,Rehovot,Israel,76100[79]The Tel-Aviv Sourasky Medical Center,Tel-Aviv,Israel,64239[80]The Chaim Sheba Medical Center,Tel-Hashomer,Israel,52621[81]AOU Policlinico S. Orsola-Malpighi,Bologna,Italy,40139[82]AOU Careggi,Firenze,Italy,50134[83]Scientific Institute Auxologico Italiano,Milano,Italy[84]Scientific institute San Raffaele,Milano,Italy[85]University Eye Clinic,Parma,Italy,43100[86]Singapore National Eye Centre,Singapore,Singapore,168751
This study will determine the effect of QPI-1007 on visual function in subjects with recent-onset NAION and assess the safety and tolerability of intravitreal injections of QPI-1007 in this population. This study will also evaluate the structural changes in the retina following administration of QPI-1007.