研究单位：[1]Second Affiliated Hospital, School of Medicine, Zhejiang University[2]Beijing Chao-Yang Hospital,Beijing,China[3]Beijing Tongren Hospital, Capital Medical University,Beijing,China[4]China-Japan Friendship Hospital,Beijing,China[5]Xinqiao Hospital，Third Military Medical University,Chongqing,Chongqing,China[6]The Second Affiliated Hospital，Fujian Medical University,Fuzhou,Fujian,China[7]Nanfang Hospital, Nanfang Medical University,Guangzhou,Guangdong,China[8]The First Affiliated Hospital,Guangzhou Medical University,Guangzhou,Guangdong,China[9]People's Hospital of Shenzhen,Shenzhen,Guangdong,China[10]Affiliated Hospital,Zhanjiang Medical College,Zhanjiang,Guangdong,China[11]Guizhou Provincial People's Hospital,Guiyang,Guizhou,China[12]Henan Provincial People's Hospital,Zhengzhou,Henan,China[13]Tongji Hospital，Tongji Medical College，Huazhong University of Science and Technology,Wuhan,Hubei,China[14]The Second Xiangya Hospital of Central South University,Changsha,Hunan,China[15]Xiangya Hospital of Central South University,Changsha,Hunan,China[16]Jiangsu Province Hospital,Nanjing,Jiangsu,China[17]The Central Hospital of Shenyang Military,Shenyang,Liaoning,China[18]The First Affiliated Hospital, China Medical University,Shenyang,Liaoning,China[19]Xijing Hospital,Xi'an,Shaanxi,China[20]Qilu Hospital, Shandong University,Jinan,Shandong,China[21]Shandong Provincal Hospital,Jinan,Shandong,China[22]Qingdao Municipal Hospital,Qingdao,Shandong,China[23]Weifang Asthma Hospital,Weifang,Shandong,China[24]Yantai liuhuanding Hospital,Yantai,Shandong,China[25]Changhai Hospital, Second Military Medical University,Shanghai,Shanghai,China[26]No.1 Hospital, Shanghai Jiaotong University,Shanghai,Shanghai,China[27]Ruijin Hospital, Shanghai Jiaotong University,Shanghai,Shanghai,China[28]Tongji Hospital, Tongji University,Shanghai,Shanghai,China[29]Xinhua Hospital, Shanghai Jiaotong University,Shanghai,Shanghai,China[30]Zhongshan Hospital, Fudan University,Shanghai,Shanghai,China[31]West China Hospital，Sichuan University,Chengdu,Sichuan,China[32]Sir Run Run Shaw hospital, College of Medicine，Zhejiang University,Hangzhou,Zhejiang,China[33]Second Affiliated Hospital, School of Medicine, Zhejiang University,Hanzhou,Zhejiang,China,310000[34]Huzhou Central Hospital,Huzhou,Zhejiang,China[35]The Second Affiliated Hospital,Wenzhou Medical University,Wenzhou,Zhejiang,China
研究目的：
Asthma, abbreviation for bronchial asthma, is one of the common chronic airways disease that threatens human health. Typical symptoms of asthma are recurrent wheezing, shortness of breath, chest tightness and cough, usually occurring at night or early morning. However, there are still some patients with only persistent clinical manifestations of chest tightness. Concerned about this group of patients, we presented a subgroup of bronchial asthma, namely, chest tightness variant asthma (CTVA). This asthma subgroup usually lacks asthma-specific clinical features such as wheezing, shortness of breath, wheezing, and therefore often misdiagnosed for a long time. In order to further understand the clinical characteristics, pathogenesis, and prognosis of patients with CTVA, we conducted a national multicenter observation study to further understand CTVA. Finally, we plan to clarify whether CTVA is a relatively independent asthma phenotype. Meanwhile, reducing misdiagnosis and perform an appropriate treatment of CTVA.
