研究单位:[1]Ruijin Hospital[2]West China Hospital, Sichuan[3]Qilu Hospital of Shandong University[4]Shanghai Jiao Tong University Affiliated Sixth People's Hospital[5]Wuhan Union Hospital, China[6]The Second Hospital of Anhui Medical University[7]Zhongda Hospital[8]The First Affiliated Hospital of Soochow University[9]China-Japan Friendship Hospital[10]Tongji Hospital[11]Beijing Hospital[12]The Second Affiliated Hospital of Dalian Medical University[13]Zhujiang Hospital[14]The First Affiliated Hospital of Anhui Medical University North District[15]Hunan Cancer Hospital[16]Liaoning Cancer Hospital & Institute[17]The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School[18]Cancer Hospital Affiliated to Xinjiang Medical University[19]The First Affiliated Hospital of Xiamen University[20]The First Affiliated Hospital of Nanchang University[21]LanZhou University[22]Central South University[23]The Affiliated Hospital of Xuzhou Medical University[24]Yunnan Cancer Hospital[25]Henan Cancer Hospital[26]Fujian Medical University Union Hospital[27]The First Hospital of Jilin University[28]The First Affiliated Hospital of Anhui Medical University[29]Gansu Cancer Hospital[30]The First Affiliated Hospital of University of Science and Technology of China[31]Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine[32]Second Affiliated Hospital of Xi'an Jiaotong University[33]First Affiliated Hospital Xi'an Jiaotong University[34]Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine[35]Shandong Cancer Hospital and Institute[36]Affiliated Cancer Hospital of Harbin Medical University[37]First Affiliated Hospital of Chongqing Medical University[38]Fudan University[39]Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Pekcing Union Medical College[40]Affiliated Hospital of Nantong University[41]Yunnan First People's Hospital[42]Shanxi Province Cancer Hospital[43]Fifth Affiliated Hospital of Guangzhou Medical University[44]Beijing Tongren Hospital[45]First Affiliated Hospital of Harbin Medical University[46]Ruian People's Hospital[47]Harbin Institute of Hematology[48]The First Affiliated Hospital of Guangzhou Medical University[49]Affiliated Hospital of Guilin Medical College[50]Air Force Medical Center. PLA[51]The Affiliated Zhongshan Hospital of Dalian University[52]Yantai Yuhuangding Hospital[53]The First Affiliated Hospital of Zhengzhou University[54]Peking University Third Hospital[55]Ruijin Hospital, Shanghai Jiao Tong University School of Medicine,Shanghai,Shanghai,China,200025
研究目的:
A multicenter, prospective, randomized, open-label, controlled trial to evaluate the efficacy and safety of genotype-guided targeted agents plus rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP-X) versus rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in patients with diffuse large B-cell lymphoma