研究单位:[1]Beijing Tiantan Hospital[2]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University[3]Beijing Tongren Hospital, Capital Medical University,Beijing,Beijing,China,100730[4]Beijing Tsinghua Changgung Hospital,Beijing,Beijing,China,102218
The management of small unruptured intracranial aneurysms (UIA) with ischemic cerebrovascular disease (ICVD) has been a very controversial topic in neurosurgery. Thus, we initiated a multicenter, prospective, randomized controlled trial (PROBE) design to elucidate in UIA patients with ICVD who do not qualify for preventive endovascular or neurosurgical intervention whether aspirin treatment decreases the risk of aneurysm growth and rupture.