研究单位:[1]BeiGene[2]Valkyrie Clinical Trials,Los Angeles,California,United States,90067[3]Cancer Care Northwest,Spokane Valley,Washington,United States,99216[4]North Shore Private Hospital,St Leonards,New South Wales,Australia,2065[5]Gold Coast Private Hospital,Gold Coast,Queensland,Australia,4215[6]Greenslopes Private Hospital,Greenslopes,Queensland,Australia,4120[7]Cancer Research South Australia,Adelaide,South Australia,Australia,5000[8]Northeast Health Wangaratta,Wangaratta,Victoria,Australia,3677[9]St John of God, Murdoch,Murdoch,Western Australia,Australia,6150[10]Anhui Provincial Cancer Hospital Aka West Branch of Anhui Province Hospital,Hefei,Anhui,China,230088[11]Beijing Tongren Hospital, Cmu,Beijing,Beijing,China,100010[12]Beijing Cancer Hospital,Beijing,Beijing,China,100142[13]Fujian Cancer Hospital,Fuzhou,Fujian,China,350014[14]The Tumor Hospital Affiliated to Guangxi Medical University,Nanning,Guangxi,China,530021[15]Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology,Wuhan,Hubei,China,430030[16]The Second Xiangya Hospital of Central South University,Changsha,Hunan,China,410011[17]Hunan Cancer Hospital,Changsha,Hunan,China,410013[18]The First Affiliated Hospital of Soochow University,Suzhou,Jiangsu,China,215006[19]The First Affiliated Hospital of Nanchang University Branch Donghu,Nanchang,Jiangxi,China,330006[20]Shandong Cancer Hospital,Jinan,Shandong,China,250117[21]Shanghai East Hospital,Shanghai,Shanghai,China,200120[22]Sichuan Cancer Hospital and Institute,Chengdu,Sichuan,China,610041[23]West China Hospital, Sichuan University,Chengdu,Sichuan,China,610041[24]Zhejiang University College of Medicine Second Affiliated Hospital,Hangzhou,Zhejiang,China,310009[25]Zhejiang Cancer Hospital,Hangzhou,Zhejiang,China,310022[26]Arensia Exploratory Medicine Llc,Tbilisi,Georgia,0112[27]Keimyung University Dongsan Hospital,Dalseogu,Daegu Gwang'yeogsi,Korea, Republic of,42601[28]National Cancer Center,Goyangsi,Gyeonggido,Korea, Republic of,10408[29]Seoul National University Bundang Hospital,Seongnamsi,Gyeonggido,Korea, Republic of,13620[30]Seoul National University Hospital,Seoul,Seoul Teugbyeolsi,Korea, Republic of,03080[31]Severance Hospital Yonsei University Health System,Seoul,Seoul Teugbyeolsi,Korea, Republic of,03722[32]Asan Medical Center,Seoul,Seoul Teugbyeolsi,Korea, Republic of,05505[33]Samsung Medical Center,Seoul,Seoul Teugbyeolsi,Korea, Republic of,06351[34]National Cheng Kung University Hospital,Tainan,Taiwan,704
研究目的:
This study is designed to evaluate the efficacy and safety of tislelizumab and tislelizumab in combination with investigational agent(s) in first-line recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC).