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Ibrutinib Combined With R-CHOP/R-DHAP in Newly Diagnosed Mantle Cell Lymphoma Patients Who Aged ≤65 Years

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研究单位: [1]Peking University Third Hospital [2]The Second Affiliated Hospital of Dalian Medical University [3]Peking University First Hospital [4]Beijing Hospital [5]Beijing Tsinghua Changgeng Hospital [6]China-Japan Friendship Hospital [7]Chinese PLA General Hospital [8]First Affiliated Hospital of Harbin Medical University [9]Baotou Cancer Hospital [10]Beijing Shijitan Hospital,Capital Medical University [11]Shanxi Province Cancer Hospital [12]Beijing Naval General Hospital [13]First Hospital of China Medical University [14]Jilin Provincial Tumor Hospital [15]Shengjing Hospital [16]307 Hospital of PLA [17]Peking Union Medical College Hospital [18]Harbin Medical University [19]Beijing Tongren Hospital

关键词: MCL ibrutinib aged ≤65 years

研究目的:
The purpose of the study is to better and systematically collect clinical data on the treatment of ibrutinib combined with R-CHOP/DHAP regimen for more scientific and accurate evaluation, our center has carried out the R-CHOP/R-DHAP alternative regimen combined with ibrutinib at age ≤ An observational clinical study on the safety and effectiveness of 65-year-old mantle cell lymphoma. Through this study, young mantle cell lymphomas in the Chinese population can be collected. Ibrutinib combined with R-CHOP/R-DHAP is used in the initial treatment. 2 and 6 cycles of ORR were used to evaluate survival indicators, and collect adverse reactions during treatment and recurrence rate after treatment.

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