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The Role of Depletion of Gut Microbiota in Osteoporosis and Osteoarthritis: A Narrative Review

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机构: [1]Tongji Univ, Dept Orthoped, Shanghai Tenth Peoples Hosp, Shanghai, Peoples R China [2]Shanghai Jiao Tong Univ, Tongren Hosp, Sch Med, Shanghai, Peoples R China [3]Xuzhou Med Univ, Dept Dermatol, Xuzhou Municipal Hosp, Xuzhou, Jiangsu, Peoples R China [4]Univ Sci & Technol China, Spine Ctr, Dept Orthoped, Affiliated Hosp 1,Div Life Sci & Med, Hefei, Peoples R China
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关键词: osteoporosis osteoarthritis gut microbiome depletion bone immune

摘要:
Osteoporosis and osteoarthritis are common diseases in an aging society, are considered metabolic diseases, and affect the quality of life of older adults. In addition, the gut microbiome is considered an additional organ to regulate bone metabolism. In the past decade, people have been studying the relationship between gut microbiota and bone metabolism. The role and mechanism of the gut microbiota in regulating bone metabolism is very important to improve the development of osteoporosis and osteoarthritis. Depletion of the gut microbiota as a method of studying the role of the gut microbiota was provided strategies to enhance the role of the gut microbiota in regulating osteoporosis and osteoarthritis. In this review, we discuss how depletion of the gut microbiota affects osteoporosis and osteoarthritis.

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出版当年[2021]版:
大类 | 3 区 医学
小类 | 3 区 内分泌学与代谢
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 内分泌学与代谢
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出版当年[2020]版:
Q1 ENDOCRINOLOGY & METABOLISM
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Q1 ENDOCRINOLOGY & METABOLISM

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第一作者机构: [1]Tongji Univ, Dept Orthoped, Shanghai Tenth Peoples Hosp, Shanghai, Peoples R China
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