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Unilateral isolated optic nerve infiltration combined with central retinal artery occlusion in a patient with acute myeloid leukemia.

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机构: [1]Department of Ophthalmology, Peking University People's Hospital, Beijing China [2]Eye Diseases and Optornetry Instiute, Bejing, China [3]Beijing Key Laboratory of Diagnosis and Therapy of Rctinal and Choroid Diseases, Beijing China [4]College of Optometry, Peking University Health Science Center, Beijing,China [5]Department of Ophthalmology, Air Force Medical Center, PLA, Beijing China
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关键词: Optic nerve infiltration Central retinal artery occlusion Acute myeloid leukemia

摘要:
To report a case of unilateral isolated optic nerve infiltration combined with central retinal artery occlusion in a patient with acute myeloid leukemia.A 28-year-old acute myeloid leukemia patient with systemic remission after hematopoietic stem cell transplantation presented with optic nerve infiltration combined with central retinal artery occlusion. Fundus examination showed diffuse papillary swelling with blurred margins and whitening macular with cherry-red spot. CBFβ-MYH11 fusion transcript analysis revealed central nervous system relapse of acute myeloid leukemia and optic nerve infiltration.Isolated optic nerve infiltration combined with central retinal artery occlusion is an extremely rare presentation in acute myeloid leukemia. Even in the absence of cytological and radiographic evidence from cerebrospinal fluid, optic nerve infiltration should not be ignored.© 2022 Published by Elsevier Inc.

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第一作者机构: [1]Department of Ophthalmology, Peking University People's Hospital, Beijing China [2]Eye Diseases and Optornetry Instiute, Bejing, China [3]Beijing Key Laboratory of Diagnosis and Therapy of Rctinal and Choroid Diseases, Beijing China [4]College of Optometry, Peking University Health Science Center, Beijing,China [5]Department of Ophthalmology, Air Force Medical Center, PLA, Beijing China
通讯作者:
通讯机构: [1]Department of Ophthalmology, Peking University People's Hospital, Beijing China [2]Eye Diseases and Optornetry Instiute, Bejing, China [3]Beijing Key Laboratory of Diagnosis and Therapy of Rctinal and Choroid Diseases, Beijing China [4]College of Optometry, Peking University Health Science Center, Beijing,China [*1]Department of Ophthalmology, Peking University People’s Hospital, Xizhimen South Street 11, Xicheng District, 100044, Beijing, China.
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