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Achieving inner aqueous drain in glaucoma secondary to iridocorneal endothelial syndrome: One year results of penetrating canaloplasty

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收录情况： ◇ SCIE

作者：
Deng Yuxuan[1] * ; Zhang Shaodan[2] * ; Ye Wenqing[2] ; Gu Juan[2] ; Lin Haishuang[2] ; Cheng Huanhuan[3] ; Xie Yanqian[2] ; Le Rongrong[2] ; Tao Yan[2] ; Zhang Wei[4] ; Chen Wei[2] ; Tham Clement C[5] ; He Mingguang[6] ; Wang Ningli[7] ; Liang Yuanbo[8,*1] ;
机构： [1]National Clinical Research Center for Ocular Diseases The Eye Hospital of Wenzhou Medical University Glaucoma Research Institute of Wenzhou Medical University, Zhejiang, China Qingdao Municipal Hospital, Qingdao, Shandong, China. [2]National Clinical Research Center for Ocular Diseases The Eye Hospital of Wenzhou Medical University Glaucoma Research Institute of Wenzhou Medical University, Zhejiang, China. [3]National Clinical Research Center for Ocular Diseases The Eye Hospital of Wenzhou Medical University Glaucoma Research Institute of Wenzhou Medical University, Zhejiang, China Wuhu First People's Hospital, Wuhu, Anhui, China. [4]Biomedical Informatics and Statistics Center, School of Public Health, Fudan University, Shanghai, China. [5]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China. [6]Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Australia. [7]Beijing Tongren Hospital, Beijing, China. [8]National Clinical Research Center for Ocular Diseases The Eye Hospital of Wenzhou Medical University Glaucoma Research Institute of Wenzhou Medical University, Zhejiang, China
出处：
DOI： 10.1016/j.ajo.2022.07.006
ISSN：

摘要：
To report the efficacy of a bleb-independent penetrating canaloplasty in the management of glaucoma secondary to iridocorneal endothelial syndrome (GS-ICE).Prospective, non-comparative clinical study.Penetrating canaloplasty was performed on 35 eyes from 35 patients with GS-ICE and medically uncontrolled IOP between January 2018 and April 2020. Patients were followed up at one week, month 1, 3, 6, 12 postoperatively, and semi-annually thereafter. Intraocular pressure (IOP), number of anti-glaucoma medication and surgery-related complications were recorded. Surgical success was defined as IOP ≥5 and ≤21mmHg without (complete success) or with/without (qualified success) IOP-lowering medications.A total of 29 eyes (82.9%) had 360° catheterization and successfully received penetrating canaloplasty. Of these eyes, 24 (82.8%) achieved qualified success and 22 (75.9%) achieved qualified success at 12 months after surgery. The mean IOP decreased from 39.5±11.8 mmHg on 2.9±1.0 medications before surgery to 16.6±5.3 mmHg (P<0.001) on 0.2±0.6 medications (P<0.001) at 12 months post-operation, respectively. Hyphema (37.9%), transient hypotony (34.5%) and transient post-operative IOP elevation (≥30mmHg, 17.9%) were the most commonly observed early complications at the one week and one month visits. From one month and beyond, all treated eyes showed no obvious bleb at the operation quadrant.Penetrating canaloplasty rescued the inner aqueous outflow in ICE eyes and demonstrated quite acceptable success in IOP control with few complications, providing a new option for the management of GS-ICE.Copyright © 2022. Published by Elsevier Inc.

基金：
National Key R&D Program of China (2020YFC2008200), Wenzhou Medical University R&D Fund (QTJ13009), Zhejiang Provincial National science foundation of China (LQ18H120010), Zhejiang Health Innovation Talents Program (2016025), key innovation and guidance program of the Eye Hospital, School of Ophthalmology & Optometry, Wenzhou Medical University (YNZD2201903), and Wenzhou Municipal Technological Innovation Program of High-level Talents (No. 604090352/577).
语种：
外文
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中科院(CAS)分区：
出版当年[2021]版：
大类 | 2 区 医学
小类 | 1 区 眼科学
最新[2025]版：
大类 | 1 区 医学
小类 | 1 区 眼科学
JCR分区：
出版当年[2020]版：
Q1 OPHTHALMOLOGY
最新[2024]版：
Q1 OPHTHALMOLOGY

影响因子： 最新[2024版] 最新五年平均 出版当年[2020版] 出版当年五年平均 出版前一年[2019版] 出版后一年[2021版]

第一作者：
第一作者机构： [1]National Clinical Research Center for Ocular Diseases The Eye Hospital of Wenzhou Medical University Glaucoma Research Institute of Wenzhou Medical University, Zhejiang, China Qingdao Municipal Hospital, Qingdao, Shandong, China.
共同第一作者：
通讯作者：
通讯机构： [8]National Clinical Research Center for Ocular Diseases The Eye Hospital of Wenzhou Medical University Glaucoma Research Institute of Wenzhou Medical University, Zhejiang, China [*1]National Clinical Research Center for Ocu- lar Diseases, The Eye Hospital of Wenzhou Medical University, Glaucoma Research Institute of Wenzhou Medical University, Wenzhou 325027, Zhejiang, China
推荐引用方式(GB/T 7714)：
Deng Yuxuan,Zhang Shaodan,Ye Wenqing,et al.Achieving inner aqueous drain in glaucoma secondary to iridocorneal endothelial syndrome: One year results of penetrating canaloplasty[J].AMERICAN JOURNAL OF OPHTHALMOLOGY.2022,243:83-90.doi:10.1016/j.ajo.2022.07.006.
APA：
Deng Yuxuan,Zhang Shaodan,Ye Wenqing,Gu Juan,Lin Haishuang...&Liang Yuanbo.(2022).Achieving inner aqueous drain in glaucoma secondary to iridocorneal endothelial syndrome: One year results of penetrating canaloplasty.AMERICAN JOURNAL OF OPHTHALMOLOGY,243,
MLA：
Deng Yuxuan,et al."Achieving inner aqueous drain in glaucoma secondary to iridocorneal endothelial syndrome: One year results of penetrating canaloplasty".AMERICAN JOURNAL OF OPHTHALMOLOGY 243.(2022):83-90

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