机构：[1]Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China首都医科大学附属北京同仁医院首都医科大学附属同仁医院[2]Department of Pathology, Beijing Tongren Hospital, Capital Medical University, Beijing, China医技科室病理科首都医科大学附属北京同仁医院首都医科大学附属同仁医院[3]Beijing Municipal Health Commission Information Center, Beijing, China[4]School of Electronic and Information Engineering, Beijing Jiaotong University, Beijing, China[5]School of Biomedical Engineering, Capital Medical University, Beijing, China[6]Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, UK[7]Liverpool Heart & Chest Hospital, Liverpool John Moores University, Liverpool, UK[8]Department of Clinical Medicine, Danish Center for Health Services Research, Aalborg University, Aalborg, Denmark[9]Clinical Medical Laboratory, Beijing Tongren Hospital, Capital Medical University, Beijing, China首都医科大学附属北京同仁医院首都医科大学附属同仁医院
BackgroundArrhythmogenic ventricular cardiomyopathy (AVC) is a common cause of ventricular arrhythmias and mortality, but limited data are available from large Asian cohorts. Our aim was to explore the current status of AVC and second, we examined the prevalence of ventricular tachycardia (VT), heart failure (HF) and mortality in patients with AVC in the Chinese population.HypothesisAt present, some studies have reported that the incidence of AVC is on the rise, which may be due to the increasing number of diagnostic methods for AVC. However, there is no epidemiological data on AVC in the Chinese population, so we speculate that the incidence of AVC in the Chinese population is increasing.Methods and ResultsWe studied 15 888 adults from the Beijing Municipal Health Commission Information Center (BMHCIC) registry database in China from January 2010 to December 2020, and calculated the average annual percentage change (AAPC). Second, we determined the incidence of VT, HF and mortality in patients with AVC. Of the 10 318 men and 5570 women who were screened by cardiac magnetic resonance or examined by myocardial biopsy, there were a total of 256 newly diagnosed AVC patients (mean [SD]: 37.54[17.10]; 39.45% female). The incidence of AVC increased from 7.60 (3.12-12.06) in 2010 to 19.62 (11.51-27.75) per 1000 person-years in 2020. Males had higher incidence of AVC than females. The AAPC for the rising incidence of AVC was 8.9 %. Males had similar VT prevalence (70.32% vs. 62.38%, p = 0.19) and mortality (1.94% vs. 1.98%, p = 0.98) but lower HF prevalence (42.58% vs. 60.40%, p = 0.006), when compared to females. Radiofrequency ablation (RFA) was more likely to be performed in males (p = 0.006).ConclusionsThe rising trend in AVC incidence was evident, with two-fold increase by 2020. Males with AVC had similar VT prevalence and mortality rate, but HF prevalence were lower than females, perhaps impacted by RFA use. We studied 15 888 adults from the Beijing Municipal Health Commission Information Center (BMHCIC) registry database in China from January 2010 to December 2020, there were a total of 256 newly diagnosed AVC patients. Males had higher incidence of AVC than females. Males had similar VT prevalence (70.32% vs. 62.38%) and mortality (1.94% vs. 1.98%) but lower HF prevalence (42.58% vs. 60.40%), when compared with females.image
第一作者机构：[1]Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[1]Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China[9]Clinical Medical Laboratory, Beijing Tongren Hospital, Capital Medical University, Beijing, China[*1]Cardiovascular Center, Beijing Tongren Hospital, Capital Medical University, No.1, Dong Jiao Min Xiang St, Dongcheng District, Beijing 100730, China.[*2]Department of Echocardiogram, Beijing Friendship Hospital, Capital Medical University, Beijing, China
推荐引用方式(GB/T 7714)：
Liu Si-Tong,Li Rui,Zheng Jian-Peng,et al.Epidemiology of arrhythmogenic ventricular cardiomyopathy in China[J].CLINICAL CARDIOLOGY.2024,47(1):doi:10.1002/clc.24160.
APA：
Liu, Si-Tong,Li, Rui,Zheng, Jian-Peng,Lu, Feng,Sun, Hui-Ni...&Bai, Ying.(2024).Epidemiology of arrhythmogenic ventricular cardiomyopathy in China.CLINICAL CARDIOLOGY,47,(1)
MLA：
Liu, Si-Tong,et al."Epidemiology of arrhythmogenic ventricular cardiomyopathy in China".CLINICAL CARDIOLOGY 47..1(2024)
