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A Case of Cryptococcosis Due to a New Cryptococcus Neoformans Sequence Type in a Patient with Human Immunodeficiency Virus Infection

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收录情况： ◇ SCIE

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机构： [1]Department of Clinical Laboratory, Beijing Youan Hospital, Capital Medical University, Beijing, China. [2]Beijing Tongren Hospital, Capital Medical University, Beijing, China.

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In this article, we report a male patient infected with HIV presenting with cryptococcal meningitis, pneumonia, and bloodstream infection, along with intestinal obstruction and gastrointestinal bleeding. Cerebrospinal fluid and bloodstream analyses revealed the presence of Cryptococcus neoformans complex. The isolated strain was sequenced and was found to belong to Cryptococcus neoformans var. grubii with a new sequence type (ST). The strain led to fatal multisystemic cryptococcosis in a short time, and the patient died due to hemorrhagic shock because of gastrointestinal bleeding despite emergency rescue efforts. There are few reports about cryptococcosis in HIV-infected patients caused by new ST isolates. We report a new Cryptococcus neoformans ST (ST702) isolate causing infection in an HIV-infected patient, which merits further study and clinical attention.

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出版当年[2025]版：

大类 | 4 区医学

小类 | 3 区热带医学 4 区公共卫生、环境卫生与职业卫生

最新[2025]版：

大类 | 4 区医学

小类 | 3 区热带医学 4 区公共卫生、环境卫生与职业卫生

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出版当年[2023]版：

Q2 TROPICAL MEDICINE Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

最新[2024]版：

Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Q3 TROPICAL MEDICINE

影响因子： 1.6 最新[2024版] 2 最新五年平均 1.9 出版当年[2023版] 2.2 出版当年五年平均 3.3 出版前一年[2022版] 1.6 出版后一年[2024版]

第一作者：

第一作者机构： [1]Department of Clinical Laboratory, Beijing Youan Hospital, Capital Medical University, Beijing, China. [2]Beijing Tongren Hospital, Capital Medical University, Beijing, China.

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