This study analyzed Global Burden of Disease (GBD) 2019 data to assess cardiovascular disease (CVD) burden in women worldwide. Using annual incident cases, deaths, age-standardized incidence (ASIR), and mortality rates (ASMR) from 1990-2019, trends were evaluated via percentage changes and estimated annual percentage change (EAPC). Globally, incident CVD cases in women rose by 73.86% (15.90 to 27.64 million), while deaths increased by 47.45% (6.06 to 8.94 million). Despite this, ASIR (EAPC: -0.57%) and ASMR (EAPC: -1.63%) declined. Regional disparities emerged in ischemic heart disease (IHD): ASIR increased in low/middle socio-demographic index (SDI) regions (EAPC: +0.04% and + 0.08%) but decreased in high-middle/high SDI regions (EAPC: -1.09% and -2.24%). Findings highlight persistent IHD incidence growth in lower-resource settings despite global improvements in age-standardized rates.
基金：
Science and Technology Development Foundation of Beijing Anzhen Hospital [AZYZR202207]; Hospital Founding of Beijing Tongren Hospital [2023-YJJ-PY-2013]
第一作者机构：[1]Capital Med Univ, Beijing Anzhen Hosp, 2 Anzhen Rd, Beijing 100029, Peoples R China[2]Beijing Inst Heart Lung & Blood Vessel Dis, Beijing, Peoples R China
通讯作者：
通讯机构：[1]Capital Med Univ, Beijing Anzhen Hosp, 2 Anzhen Rd, Beijing 100029, Peoples R China[2]Beijing Inst Heart Lung & Blood Vessel Dis, Beijing, Peoples R China
推荐引用方式(GB/T 7714)：
Li Yan,Yin Na,Li Chao,et al.Global burden of cardiovascular disease in women, 1990-2019: A systematic analysis for the Global Burden of Disease Study 2019[J].MEDICINE.2025,104(27):doi:10.1097/MD.0000000000043215.
APA：
Li, Yan,Yin, Na,Li, Chao&Yang, Shi-Wei.(2025).Global burden of cardiovascular disease in women, 1990-2019: A systematic analysis for the Global Burden of Disease Study 2019.MEDICINE,104,(27)
MLA：
Li, Yan,et al."Global burden of cardiovascular disease in women, 1990-2019: A systematic analysis for the Global Burden of Disease Study 2019".MEDICINE 104..27(2025)
