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Controversies, consensuses, and guidelines for acute primary angle closure attack (APACA) by the Asia-Pacific Glaucoma Society (APGS) and the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO)

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机构: [1]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China [2]Lam Kin Chung. Jet King-Shing Ho Glaucoma Treatment and Research Centre, The Chinese University of Hong Kong, Hong Kong SAR, China [3]Hong Kong Eye Hospital, Hong Kong SAR, China. [4]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Disease, Guangzhou, China. [5]Singapore National Eye Centre, Singapore Eye Research Institute, Singapore. [6]Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. [7]Centre for Public Health, Queen's University Belfast, Belfast, UK [8]Orbis International, New York, NY, USA. [9]Department of Ophthalmology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. [10]International Specialist Eye Centre, Kuala Lumpur, Malaysia. [11]Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia [12]Ophthalmology, Department of Surgery, Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Melbourne, Victoria, Australia [13]School of Optometry, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China [14]Research Centre for SHARP Vision (RCSV), The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China [15]Centre for Eye and Vision Research (CEVR), Kowloon, Hong Kong SAR, China. [16]Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, South Korea. [17]Department of Ophthalmology, LKS Faculty of Medicine, The University of Hong Kong, Room 301, Level 3, Block B, Cyberport 4, 100 Cyberport Road, Hong Kong SAR, China. [18]The C-MER International Eye Research Center of The Chinese University of Hong Kong (Shenzhen), Shenzhen, China [19]The C-MER Dennis Lam and Partners Eye Center, C-MER International Eye Care Group, Hong Kong SAR, China. [20]National Clinical Research Center for Ocular Diseases, Eye Hospital of Wenzhou Medical University, Wenzhou, China. [21]Glaucoma Services, Medical Research Foundation, Chennai, Tamil Nadu, India. [22]Viterbi Family Department of Ophthalmology, UC San Diego, San Diego, CA, USA [23]Division of Oculofacial Plastic and Reconstructive Surgery, UC San Diego Department of Ophthalmology, La Jolla, CA, USA. [24]Chulalongkorn University & King Chulalongkorn Memorial Hospital, Bangkok, Thailand. [25]Department of Ophthalmology and Visual Science, Eye, Ear, Nose and Throat Hospital, Shanghai Medical College of Fudan University, Shanghai, China [26]Key NHC Key Laboratory of Myopia (Fudan University), Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China. [27]Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing, China. [28]Department of Ophthalmology and Visual Sciences, The Prince of Wales Hospital, Hong Kong SAR, China [29]Hong Kong Hub of Paediatric Excellence, The Chinese University of Hong Kong, Hong Kong SAR, China [30]Department of Ophthalmology, Hong Kong Children's Hospital, Hong Kong SAR, China.
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关键词: Consensus Acute Primary Angle Closure Attack Glaucoma

摘要:
The Asia-Pacific Glaucoma Society (APGS), in collaboration with the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), convened a panel of 18 international experts from 10 countries/territories to identify areas of controversy and establish consensus on diagnosing and managing Acute Primary Angle Closure Attack (APACA). APACA is a relatively common and potentially vision-threatening ocular emergency, particularly in Chinese and Asian populations. With timely and appropriate intervention, favorable outcomes could be achieved. However, with the current treatment protocol, two areas need to be improved: 1) more rapid and consistent reduction of intraocular pressure (IOP), and 2) reducing the proportion of patients who develop chronic IOP elevation after resolution of an acute attack and successful laser peripheral iridotomy. The international panel of experts systematically revisited and debated alternative treatments to address the above issues. Consensus was evaluated using a five-point Likert scale (strongly agree, agree, neutral, disagree, and strongly disagree), in which each expert considered and voted anonymously and independently on each consensus statement. A statement consensus is established when the summation of votes for "agree" and "strongly agree" reaches a 75 % threshold. Argon laser peripheral iridoplasty, anterior chamber paracentesis, and laser pupilloplasty are considered appropriate and suitable options for rapid IOP reduction. Earlier phacoemulsification is effective in preventing further retinal ganglion cell loss and disease progression after APACA and is worth considering, provided adequate facilities and expertise are available. Further studies are warranted to evaluate the safety and efficacy of corneal indentation as a rapid and immediate treatment to lower IOP.Copyright © 2025. Published by Elsevier Inc.

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大类 | 2 区 医学
小类 | 2 区 眼科学
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大类 | 2 区 医学
小类 | 2 区 眼科学
第一作者:
第一作者机构: [1]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China [2]Lam Kin Chung. Jet King-Shing Ho Glaucoma Treatment and Research Centre, The Chinese University of Hong Kong, Hong Kong SAR, China [3]Hong Kong Eye Hospital, Hong Kong SAR, China. [28]Department of Ophthalmology and Visual Sciences, The Prince of Wales Hospital, Hong Kong SAR, China
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通讯作者:
通讯机构: [1]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China [2]Lam Kin Chung. Jet King-Shing Ho Glaucoma Treatment and Research Centre, The Chinese University of Hong Kong, Hong Kong SAR, China [3]Hong Kong Eye Hospital, Hong Kong SAR, China. [28]Department of Ophthalmology and Visual Sciences, The Prince of Wales Hospital, Hong Kong SAR, China [29]Hong Kong Hub of Paediatric Excellence, The Chinese University of Hong Kong, Hong Kong SAR, China [30]Department of Ophthalmology, Hong Kong Children's Hospital, Hong Kong SAR, China.
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