个人科研网厅 | | 帮助
高级检索
当前位置： 首页 > 详情页

The X-Age Project to construct a Chinese aging clock

| 认领 | 导出 | |

文献详情

资源类型：
Pubmed体系：
作者：
Li Jiaming[1,2] * ; Jiang Mengmeng[1,3] ; Wang Qiaoran[1,2] ; Zheng Zikai[1,2] ; Shen Jianghua[1,3] ; Li Jingyi[1,3] ; Xiong Muzhao[1,2] ; Zheng Yandong[1,4] ; Lu Xiaoyong[1,2] ; Cai Yusheng[1,3] ; Fan Yanling[1,2] ; Geng Lingling[1,4] ; Ji Qianzhao[1,5] ; Peng Qianqian[1,6] ; Sun Shuhui[1,7] ; Wang Yuanyuan[1,8] ; Xin Zijuan[1,3] ; Yan Kaowen[1,3] ; Yang Yuanhan[1,3] ; Yu Jun[1,9] ; Yan Haoteng[1,4] ; Ai Ding[10,11] ; Bai Yongping[12,13] ; Bi Yan[14,15] ; Bian Xiu-Wu[16,17] ; Bu Pengcheng[18,19] ; Cai Jian-Ping[20,21] ; Cao Chun-Mei[22,23] ; Cao Feng[24,25] ; Cao Zhongwei[26,27] ; Chai Renjie[28,29] ; Chan Piu[30,31] ; Chen Chang[32,33] ; Chen Cheng-Shui[34,35] ; Chen Chunying[36,37] ; Chen Di[38,39] ; Chen Hou-Zao[40,41] ; Chen Lin[42,43] ; Chen Quan[44,45] ; Chen Xiao[46,47] ; Chen Xiaochun[48,49] ; Chen Yu[50,51] ; Chen Zi-Jiang[52,53] ; Ci Weimin[54,55] ; Dai Zhe[56,57] ; Ding Qiurong[58,59] ; Dong Birong[60,61] ; Dong Jiahong[62,63] ; Fan Jian-Gao[64,65] ; Feng Shiqing[66,67] ; Feng Xin[68,69] ; Feng Yun[70,71] ; Fu Xiaobing[72,73] ; Fu Xiaolong[74,75] ; Gao Feng[76,77] ; Gao Jiangang[78,79] ; Gao Qiang[80,81] ; Gao Shaorong[82,83] ; Gu Yonghao[84,85] ; Guan Youfei[86,87] ; Guo Feifan[88,89] ; Han Jing-Dong J[90,91] ; Hao Haiping[92,93] ; Hao Jihui[94,95] ; He Fuchu[96,97,98] ; He Jinhan[99,100] ; He Ming[101,102] ; He Mingguang[103,104] ; He Qiyang[105,106] ; He Zhiying[107,108] ; He Zuhong[109,110] ; Hong Huashan[111,112] ; Hong Jiaxu[113,114] ; Hou Shengping[115,116] ; Hu Cheng[117,118] ; Hu Ping[119,120] ; Hu Zhibin[121,122] ; Huang Canhua[123,124] ; Huang Jun[125,126] ; Huang Kai[127,128] ; Huang Pengyu[129,130] ; Ji Xunming[131,132] ; Ji Yong[133,134] ; Jia Shunji[135,136] ; Jiang Hong[137,138] ; Jiang Wenjian[139,140] ; Jin Lingjing[141,142] ; Jin Zi-Bing[143,144] ; Ju Shenghong[145,146] ; Ju Zhenyu[147,148] ; Kong Qing-Peng[149,150] ; Kong Wei[151,152] ; Kong Wei-Jia[153,154] ; Kong Xiangqing[155,156] ; Lei Guanghua[157,158] ; Li Geng-Lin[159,160] ; Li Ji[161,162] ; Li Jian[163,164] ; Li Mengfeng[165,166] ; Li Rong[167,168] ; Li Wei[169,170] ; Li Wei[171,172] ; Li Xiao-Jun[173,174] ; Li Xin[175,176] ; Liang Qingfeng[177,178] ; Liang Zhen[179,180] ; Lin Haotian[181,182] ; Liu Baohua[183,184] ; Liu Cai-Yue[185,186] ; Liu Changsheng[187,188] ; Liu Feng[189,190] ; Liu Jianfeng[191,192] ; Liu Jun-Ping[193,194] ; Liu Ke[195,196] ; Liu Lin[197,198] ; Liu Pingsheng[199,200] ; Liu Qiang[201,202] ; Liu Qiang[203,204] ; Liu Tiemin[205,206] ; Liu Wenwen[207,208] ; Liu Xingguo[209,210] ; Liu Yajun[211,212] ; Liu Yong[213,214] ; Liu Youhua[215,216] ; Liu Youshuo[217,218] ; Liu Zhili[219,220] ; Long Xiao[221,222] ; Lu Yao[223,224] ; Luo Jian[225,226] ; Luo Xianghang[227,228] ; Ma Chunhong[229,230] ; Ma Shuai[231,232] ; Ma Xinran[233,234] ; Mao Jianhua[235,236] ; Mao Zhiyong[237,238] ; Ng Shyh-Chang[239,240] ; Nie Guangjun[241,242] ; Niu Yuyu[243,244] ; Peng Yaojin[245,246] ; Pu Jun[247,248] ; Qi Jieyu[249,250] ; Qiang Li[251,252] ; Qiao Jie[253,254] ; Qin Yingying[255,256] ; Qu Aijuan[257,258] ; Qu Jing[259,260] ; Ren Jie[261,262] ; Ren Ruibao[263,264] ; Ruan Xiong Z[265,266] ; Shi Anbing[267,268] ; Shi Haibo[269,270] ; Shi Jie[271,272] ; So Kwok-Fai[273,274] ; Song Moshi[275,276] ; Song Weihong[277,278] ; Songyang Zhou[279,280] ; Su Jiacan[281,282] ; Sun Aijun[283,284] ; Sun Liang[285,286] ; Sun Qiang[287,288] ; Sun Yi Eve[289,290] ; Sun Yu[291,292] ; Tang Peifu[293,294] ; Tang Qi-Qun[295,296] ; Tang Yi[297,298] ; Tao Jun[299,300] ; Tao Ling[301,302] ; Tian Mei[303,304] ; Tian Xiao-Li[305,306] ; Tian Ye[307,308] ; Tong Xiaolin[309,310] ; Wang Cong-Yi[311,312] ; Wang Haibo[313,314] ; Wang Hongmei[315,316] ; Wang Huating[317,318] ; Wang Jianan[319,320] ; Wang Jianwei[321,322] ; Wang Jianwei[323,324] ; Wang Jiqiu[325,326] ; Wang Liheng[327,328] ; Wang Lin[329,330] ; Wang Miao[331,332] ; Wang Qiang[333,334] ; Wang Si[335,336] ; Wang Sijia[337,338] ; Wang Songlin[339,340] ; Wang Wengong[341,342] ; Wang Xiaoming[343,344] ; Wang Xiaoning[345,346] ; Wang Yan[347,348] ; Wang Yan-Jiang[349,350] ; Wang Yuan[351,352] ; Wang Yunfang[353,354] ; Wang Zhenning[355,356] ; Wei Xiawei[357,358] ; Weng Jianping[359,360] ; Wu Haitao[361,362] ; Wu Jihong[363,364] ; Xia Xiaohuan[365,366] ; Xia Yang[367,368] ; Xiang Andy Peng[369,370] ; Xiao Guozhi[371,372] ; Xiao Junjie[373,374] ; Xiao Yichuan[375,376] ; Xiao Zhi-Xiong Jim[377,378] ; Xie Zhengwei[379,380] ; Xiong Wei[381,382] ; Xu Aimin[383,384] ; Xu Hua[385,386] ; Xu Lingyan[387,388] ; Xu Ming[389,390] ; Yan Liying[391,392] ; Yang Jiayin[393,394] ; Yang Jichun[395,396] ; Yang Liu[397,398] ; Yang Yun-Gui[399,400] ; Yang Ze[401,402] ; Yang Zhenglin[403,404] ; Yao Hongjie[405,406] ; Ye Jing[407,408] ; Yi Chengqi[409,410] ; Yi Fan[411,412] ; Yu Honghua[413,414] ; Yu Yang[415,416] ; Yu Zhengrong[417,418] ; Yuan Ti-Fei[419,420] ; Yue Jirong[421,422] ; Yue Rui[423,424] ; Zhang Chen[425,426] ; Zhang Chunxiang[427,428] ; Zhang Cuntai[429,430] ; Zhang Feng[431,432] ; Zhang Hongbo[433,434] ; Zhang Hongjia[435,436] ; Zhang Huijie[437,438] ; Zhang Jie[439,440] ; Zhang Jingjing[441,442] ; Zhang Licheng[443,444] ; Zhang Lingqiang[445,446,447] ; Zhang Luoying[448,449] ; Zhang Qingjiong[450,451] ; Zhang Wei[452,453] ; Zhang Weiping J[454,455] ; Zhang Xin[456,457] ; Zhang Xuan[458,459] ; Zhang Yong[460,461] ; Zhang Yun-Wu[462,463] ; Zhang Zhanjun[464,465] ; Zhang Zhuohua[466,467] ; Zhao Bing[468,469] ; Zhao Guoguang[470,471] ; Zhao Jiajun[472,473] ; Zhao Meng[474,475] ; Zhao Tongbiao[476,477] ; Zheng Jialin C[478,479] ; Zheng Junke[480,481] ; Zheng Zhuozhao[482,483] ; Zhou Huixia[484,485] ; Zhou Lili[486,487] ; Zhou Xiangtian[488,489] ; Zhou Yongsheng[490,491] ; Zhou Zhongjun[492,493] ; Zhu Lan[494,495] ; Zhu Yizhun[496,497] ; Zhu Zhiming[498,499] ; Zhuang Wenjuan[500,501] ; Zou Weiguo[502,503] ; Zhang Weiqi[504,505] ; Pei Gang[506,507] ; Liu Guang-Hui[508,509] ;
机构： [1]Aging Biomarker Consortium (ABC), Beijing, China. [2]China National Center for Bioinformation, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China. [3]State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. [4]Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing, China. [5]Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China. [6]CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China. [7]Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China. [8]State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China. [9]Pancreas Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China. [10]Aging Biomarker Consortium (ABC), Beijing, China. edin2000cn@163.com. [11]State Key Laboratory of Experimental Hematology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin, China. edin2000cn@163.com. [12]Aging Biomarker Consortium (ABC), Beijing, China. baiyongping@csu.edu.cn. [13]Department of Cardiovascular Medicine, Coronary Circulation Center, Xiangya Hospital, Central South University National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China. baiyongping@csu.edu.cn. [14]Aging Biomarker Consortium (ABC), Beijing, China. biyan@nju.edu.cn. [15]Department of Endocrinology, Endocrine and Metabolic Disease Medical Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. biyan@nju.edu.cn. [16]Aging Biomarker Consortium (ABC), Beijing, China. bianxiuwu@263.net. [17]Institute of Pathology and Southwest Cancer Center, and Key Laboratory of Tumor Immunopathology of the Ministry of Education of China, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China. bianxiuwu@263.net. [18]Aging Biomarker Consortium (ABC), Beijing, China. bupc@ibp.ac.cn. [19]Key Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China. bupc@ibp.ac.cn. [20]Aging Biomarker Consortium (ABC), Beijing, China. caijp61@vip.sina.com. [21]The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology of National Health Commission, Beijing, China. caijp61@vip.sina.com. [22]Aging Biomarker Consortium (ABC), Beijing, China. caochunmei@pku.edu.cn. [23]Laboratory of Cardiovascular Science, Beijing Clinical Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China. caochunmei@pku.edu.cn. [24]Aging Biomarker Consortium (ABC), Beijing, China. fengcao8828@163.com. [25]National Research Center for Geriatic Diseases and Institute of Geriatic Medicine, 2nd Medical Center, Chinese PLA General Hospital, Beijing, China. fengcao8828@163.com. [26]Aging Biomarker Consortium (ABC), Beijing, China. zhongweicao@scu.edu.cn. [27]State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, China. zhongweicao@scu.edu.cn. [28]Aging Biomarker Consortium (ABC), Beijing, China. renjiec@seu.edu.cn. [29]State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China. renjiec@seu.edu.cn. [30]Aging Biomarker Consortium (ABC), Beijing, China. pbchan@hotmail.com. [31]Department of Neurology and Neurobiology, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital of Capital Medical University, Beijing, China. pbchan@hotmail.com. [32]Aging Biomarker Consortium (ABC), Beijing, China. changchen@ibp.ac.cn. [33]National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China. changchen@ibp.ac.cn. [34]Aging Biomarker Consortium (ABC), Beijing, China. chenchengshui@wmu.edu.cn. [35]Department of Respiratory and Critical Care, Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, China. chenchengshui@wmu.edu.cn. [36]Aging Biomarker Consortium (ABC), Beijing, China. chenchy@nanoctr.cn. [37]New Cornerstone Science Laboratory, CAS Key Lab for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, China. chenchy@nanoctr.cn. [38]Aging Biomarker Consortium (ABC), Beijing, China. di.chen@siat.ac.cn. [39]Faculty of Pharmaceutical Sciences, Shenzhen University of Advanced Technology, Shenzhen, China. di.chen@siat.ac.cn. [40]Aging Biomarker Consortium (ABC), Beijing, China. chenhouzao@ibms.cams.cn. [41]State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. chenhouzao@ibms.cams.cn. [42]Aging Biomarker Consortium (ABC), Beijing, China. linchen70@163.com. [43]Department of Wound Repair and Rehabilitation Medicine, State Key Laboratory of Trauma and Chemical Poisoning, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, China. linchen70@163.com. [44]Aging Biomarker Consortium (ABC), Beijing, China. chenq@nankai.edu.cn. [45]School of Medicine, Nankai University, Tianjin, China. chenq@nankai.edu.cn. [46]Aging Biomarker Consortium (ABC), Beijing, China. sirchenxiao@126.com. [47]Department of Orthopedic, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. sirchenxiao@126.com. [48]Aging Biomarker Consortium (ABC), Beijing, China. chenxc998@fjmu.edu.cn. [49]Department of Neurology, Fujian Medical University Union Hospital, Fujian Key Laboratory of Molecular Neurology and Institute of Neuroscience, Fujian Medical University, Fuzhou, China. chenxc998@fjmu.edu.cn. [50]Aging Biomarker Consortium (ABC), Beijing, China. yu.chen@siat.ac.cn. [51]The Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science, Shenzhen, China. yu.chen@siat.ac.cn. [52]Aging Biomarker Consortium (ABC), Beijing, China. chenzijiang@hotmail.com. [53]State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Shandong, China. chenzijiang@hotmail.com. [54]Aging Biomarker Consortium (ABC), Beijing, China. ciwm@foxmail.com. [55]Department of Urology, Chinese PLA General Hospital, Beijing, China. ciwm@foxmail.com. [56]Aging Biomarker Consortium (ABC), Beijing, China. daizhe@znhospital.cn. [57]Department of Endocrinology, Zhongnan Hospital of Wuhan University, Wuhan, China. daizhe@znhospital.cn. [58]Aging Biomarker Consortium (ABC), Beijing, China. qrding@sinh.ac.cn. [59]CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China. qrding@sinh.ac.cn. [60]Aging Biomarker Consortium (ABC), Beijing, China. birongdong123@outlook.com. [61]West China Hospital of Sichuan University, the Center of Gerontology and Geriatrics and National Clinical Research Center for Geriatrics, Chengdu, China. birongdong123@outlook.com. [62]Aging Biomarker Consortium (ABC), Beijing, China. dongjiahong@tsinghua.edu.cn. [63]Hepato-Pancreato-Biliary Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. dongjiahong@tsinghua.edu.cn. [64]Aging Biomarker Consortium (ABC), Beijing, China. fanjiangao@xinhuamed.com.cn. [65]Department of Gastroenterology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. fanjiangao@xinhuamed.com.cn. [66]Aging Biomarker Consortium (ABC), Beijing, China. shiqingfeng@sdu.edu.cn. [67]Department of Orthopaedics, Qilu Hospital of Shandong University, Shandong University Centre for Orthopaedics, Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, China. shiqingfeng@sdu.edu.cn. [68]Aging Biomarker Consortium (ABC), Beijing, China. xin.feng@ia.ac.cn. [69]CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing, China. xin.feng@ia.ac.cn. [70]Aging Biomarker Consortium (ABC), Beijing, China. fengyun@bjmu.edu.cn. [71]Department of Ophthalmology, Peking University First Hospital, Beijing, China. fengyun@bjmu.edu.cn. [72]Aging Biomarker Consortium (ABC), Beijing, China. fuxiaobing@vip.sina.com. [73]Tissue Repair and Regeneration Research Center, Medical Innovation Department, PLA General Hospital and Medical College, Beijing, China. fuxiaobing@vip.sina.com. [74]Aging Biomarker Consortium (ABC), Beijing, China. fuxiaolongshifan@163.com. [75]Shandong Provincial Hospital, Medical Science and Technology Innovation Center, School of Clinical and Basic Medical Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China. fuxiaolongshifan@163.com. [76]Aging Biomarker Consortium (ABC), Beijing, China. fgao@fmmu.edu.cn. [77]Key Laboratory of Aerospace Medicine, Ministry of Education, School of Aerospace Medicine, Air Force Medical University, Xi'an, China. fgao@fmmu.edu.cn. [78]Aging Biomarker Consortium (ABC), Beijing, China. jggao@sdu.edu.cn. [79]School of Life Science, Shandong University, Jinan, China. jggao@sdu.edu.cn. [80]Aging Biomarker Consortium (ABC), Beijing, China. gaoqiang@fudan.edu.cn. [81]Department of Hepatobiliary Surgery and Transplantation, Liver Cancer Institute and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Zhongshan Hospital, Fudan University, Shanghai, China. gaoqiang@fudan.edu.cn. [82]Aging Biomarker Consortium (ABC), Beijing, China. gaoshaorong@tongji.edu.cn. [83]Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Frontier Science Center for Stem Cells, School of Life Sciences and Technology, Tongji University, Shanghai, China. gaoshaorong@tongji.edu.cn. [84]Aging Biomarker Consortium (ABC), Beijing, China. guyh@ustc.edu.cn. [85]Department of Ophthalmology, First Affiliated Hospital of University of Science and Technology of China, Hefei, China. guyh@ustc.edu.cn. [86]Aging Biomarker Consortium (ABC), Beijing, China. guanyf@dmu.edu.cn. [87]Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, China. guanyf@dmu.edu.cn. [88]Aging Biomarker Consortium (ABC), Beijing, China. ffguo@fudan.edu.cn. [89]Zhongshan Hospital, State Key Laboratory of Brain Function and Disorders, Institute for Translational Brain Research, Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China. ffguo@fudan.edu.cn. [90]Aging Biomarker Consortium (ABC), Beijing, China. jackie.han@pku.edu.cn. [91]Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Center for Quantitative Biology, Peking University, Beijing, China. jackie.han@pku.edu.cn. [92]Aging Biomarker Consortium (ABC), Beijing, China. Haipinghao@cpu.edu.cn. [93]State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China. Haipinghao@cpu.edu.cn. [94]Aging Biomarker Consortium (ABC), Beijing, China. haojihui@tjmuch.com. [95]Pancreas Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine, Tianjin Key Laboratory of Digestive Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China. haojihui@tjmuch.com. [96]Aging Biomarker Consortium (ABC), Beijing, China. hefc@bmi.ac.cn. [97]State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China. hefc@bmi.ac.cn. [98]The &#x3c0 [99]-HuB Consortium, Beijing, China. hefc@bmi.ac.cn. [99]Aging Biomarker Consortium (ABC), Beijing, China. jinhanhe@scu.edu.cn. [100]Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, China. jinhanhe@scu.edu.cn. [101]Aging Biomarker Consortium (ABC), Beijing, China. heming@shsmu.edu.cn. [102]Institute for Translational Medicine on Cell Fate and Disease, Shanghai Ninth People's Hospital, Key Laboratory of Cell Differentiation and Apoptosis of the National Ministry of Education, Department of Pathophysiology, Department of Orthopedic, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. heming@shsmu.edu.cn. [103]Aging Biomarker Consortium (ABC), Beijing, China. mingguang_he@yahoo.com. [104]The Hong Kong Polytechnic University, Hong Kong, China. mingguang_he@yahoo.com. [105]Aging Biomarker Consortium (ABC), Beijing, China. qiyang_he@vip.163.com. [106]Institute of Medicinal Biotechnology, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China. qiyang_he@vip.163.com. [107]Aging Biomarker Consortium (ABC), Beijing, China. zyhe@tongji.edu.cn. [108]Institute for Regenerative Medicine, Medical Innovation Center and State Key Laboratory of Cardiovascular Diseases, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China. zyhe@tongji.edu.cn. [109]Aging Biomarker Consortium (ABC), Beijing, China. hezuhong@163.com. [110]Department of Otorhinolaryngology-Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China. hezuhong@163.com. [111]Aging Biomarker Consortium (ABC), Beijing, China. 15959159898@163.com. [112]Fujian Key Laboratory of Vascular Aging, Fujian Medical University Union Hospital, Fujian, China. 15959159898@163.com. [113]Aging Biomarker Consortium (ABC), Beijing, China. jiaxu.hong@fdeent.org. [114]Department of Ophthalmology, Eye and ENT Hospital, Shanghai Key Lab of Rare Disease Gene Editing and Cell Therapy, State Key Laboratory of Brain Function and Disorders, Fudan University, Shanghai, China. jiaxu.hong@fdeent.org. [115]Aging Biomarker Consortium (ABC), Beijing, China. sphou828@163.com. [116]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China. sphou828@163.com. [117]Aging Biomarker Consortium (ABC), Beijing, China. alfredhc@sjtu.edu.cn. [118]Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Centre for Diabetes, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. alfredhc@sjtu.edu.cn. [119]Aging Biomarker Consortium (ABC), Beijing, China. hup@sibcb.ac.cn. [120]Guangzhou Laboratory, Guangzhou, China. hup@sibcb.ac.cn. [121]Aging Biomarker Consortium (ABC), Beijing, China. zhibin_hu@njmu.edu.cn. [122]State Key Laboratory of Reproductive Medicine and Offspring Health, Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China. zhibin_hu@njmu.edu.cn. [123]Aging Biomarker Consortium (ABC), Beijing, China. hcanhua@scu.edu.cn. [124]Department of Biotherapy, Oxidative Stress Research Center, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China. hcanhua@scu.edu.cn. [125]Aging Biomarker Consortium (ABC), Beijing, China. jhuang@zju.edu.cn. [126]Zhejiang Key Laboratory of Geriatrics and Geriatrics Institute of Zhejiang Province, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, China. jhuang@zju.edu.cn. [127]Aging Biomarker Consortium (ABC), Beijing, China. huangkai1@hust.edu.cn. [128]Clinic Center of Human Gene Research, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. huangkai1@hust.edu.cn. [129]Aging Biomarker Consortium (ABC), Beijing, China. huangpengyu@yeah.net. [130]State Key Laboratory of Advanced Medical Materials and Devices, Engineering Research Center of Pulmonary and Critical Care Medicine Technology and Device (Ministry of Education), Institute of Biomedical Engineering, Tianjin Institutes of Health Science, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, China. huangpengyu@yeah.net. [131]Aging Biomarker Consortium (ABC), Beijing, China. jixm@ccmu.edu.cn. [132]Beijing Institute of Brain Disorders, Department of Neurology and Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China. jixm@ccmu.edu.cn. [133]Aging Biomarker Consortium (ABC), Beijing, China. yongji@hrbmu.edu.cn. [134]State Key Laboratory of Frigid Zone Cardiovascular Diseases, Harbin Medical University, Harbin, China. yongji@hrbmu.edu.cn. [135]Aging Biomarker Consortium (ABC), Beijing, China. jiasj@genetics.ac.cn. [136]Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China. jiasj@genetics.ac.cn. [137]Aging Biomarker Consortium (ABC), Beijing, China. jianghong@uhrs.edu.cn. [138]University of Health and Rehabilitation Sciences, Qingdao, China. jianghong@uhrs.edu.cn. [139]Aging Biomarker Consortium (ABC), Beijing, China. jiangwenjian@ccmu.edu.cn. [140]Beijing Anzhen Hospital, Capital Medical University, Beijing, China. jiangwenjian@ccmu.edu.cn. [141]Aging Biomarker Consortium (ABC), Beijing, China. lingjingjin@163.com. [142]Department of Neurology and Neurological Rehabilitation, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai, China. lingjingjin@163.com. [143]Aging Biomarker Consortium (ABC), Beijing, China. jinzb502@ccmu.edu.cn. [144]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China. jinzb502@ccmu.edu.cn. [145]Aging Biomarker Consortium (ABC), Beijing, China. jsh@seu.edu.cn. [146]Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging and Interventional Radiology (Southeast University), Department of Radiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, China. jsh@seu.edu.cn. [147]Aging Biomarker Consortium (ABC), Beijing, China. zhenyuju2016@jnu.edu.cn. [148]Key Laboratory of Regenerative Medicine of the Ministry of Education, Institute of Aging and Regenerative Medicine, Department of Developmental and Regenerative Medicine, College of Life Science and Technology, Jinan University, Guangzhou, China. zhenyuju2016@jnu.edu.cn. [149]Aging Biomarker Consortium (ABC), Beijing, China. kongqp@mail.kiz.ac.cn. [150]State Key Laboratory of Genetic Evolution and Animal Models, Key Laboratory of Healthy Aging Research of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China. kongqp@mail.kiz.ac.cn. [151]Aging Biomarker Consortium (ABC), Beijing, China. kongw@bjmu.edu.cn. [152]Department of Physiology and Pathophysiology, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China. kongw@bjmu.edu.cn. [153]Aging Biomarker Consortium (ABC), Beijing, China. entwjkong@hust.edu.cn. [154]Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. entwjkong@hust.edu.cn. [155]Aging Biomarker Consortium (ABC), Beijing, China. kongxq@njmu.edu.cn. [156]Department of Cardiology, the First Affiliated Hospital with Nanjing Medical University, Nanjing, China. kongxq@njmu.edu.cn. [157]Aging Biomarker Consortium (ABC), Beijing, China. lei_guanghua@csu.edu.cn. [158]Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China. lei_guanghua@csu.edu.cn. [159]Aging Biomarker Consortium (ABC), Beijing, China. genglin.li@fdeent.org. [160]Department of Otorhinolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, China. genglin.li@fdeent.org. [161]Aging Biomarker Consortium (ABC), Beijing, China. liji_xy@csu.edu.cn. [162]Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China. liji_xy@csu.edu.cn. [163]Aging Biomarker Consortium (ABC), Beijing, China. lijian@bjhmoh.cn. [164]The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology of National Health Commission, Beijing, China. lijian@bjhmoh.cn. [165]Aging Biomarker Consortium (ABC), Beijing, China. limf@mail.sysu.edu.cn. [166]Cancer Institute, Southern Medical University, Guangzhou, China. limf@mail.sysu.edu.cn. [167]Aging Biomarker Consortium (ABC), Beijing, China. roseli001@sina.com. [168]State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China. roseli001@sina.com. [169]Aging Biomarker Consortium (ABC), Beijing, China. leways@gwcmc.org. [170]Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. leways@gwcmc.org. [171]Aging Biomarker Consortium (ABC), Beijing, China. liwei@ioz.ac.cn. [172]State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. liwei@ioz.ac.cn. [173]Aging Biomarker Consortium (ABC), Beijing, China. lixiaojun4183@xjtu.edu.cn. [174]Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, China. lixiaojun4183@xjtu.edu.cn. [175]Aging Biomarker Consortium (ABC), Beijing, China. xinli@ioz.ac.cn. [176]Institute of Zoology, Chinese Academy of Sciences, Beijing, China. xinli@ioz.ac.cn. [177]Aging Biomarker Consortium (ABC), Beijing, China. liangqingfeng@ccmu.edu.cn. [178]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China. liangqingfeng@ccmu.edu.cn. [179]Aging Biomarker Consortium (ABC), Beijing, China. liangzhen@pkuszh.com. [180]Department of Geriatrics, Peking University Shenzhen Hospital, Shenzhen, China. liangzhen@pkuszh.com. [181]Aging Biomarker Consortium (ABC), Beijing, China. linht5@mail.sysu.edu.cn. [182]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Vision Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China. linht5@mail.sysu.edu.cn. [183]Aging Biomarker Consortium (ABC), Beijing, China. ppliew@szu.edu.cn. [184]Shenzhen Key Laboratory for Systemic Aging and Intervention, School of Basic Medical Sciences, Shenzhen University, Shenzhen, China. ppliew@szu.edu.cn. [185]Aging Biomarker Consortium (ABC), Beijing, China. yueyue1888@hotmail.com. [186]Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yueyue1888@hotmail.com. [187]Aging Biomarker Consortium (ABC), Beijing, China. liucs@ecust.edu.cn. [188]Engineering Research Center for Biomaterials of the Ministry of Education, East China University of Science and Technology, Shanghai, China. liucs@ecust.edu.cn. [189]Aging Biomarker Consortium (ABC), Beijing, China. liuf001@csu.edu.cn. [190]Metabolic Syndrome Research Center, the Second Xiangya Hospital of Central South University, Changsha, China. liuf001@csu.edu.cn. [191]Aging Biomarker Consortium (ABC), Beijing, China. jfliu@mail.hust.edu.cn. [192]College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China. jfliu@mail.hust.edu.cn. [193]Aging Biomarker Consortium (ABC), Beijing, China. jun-ping.liu@monash.edu. [194]Institute of Ageing Research, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China. jun-ping.liu@monash.edu. [195]Aging Biomarker Consortium (ABC), Beijing, China. liuke@ccmu.edu.cn. [196]Department of Otolaryngology, Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China. liuke@ccmu.edu.cn. [197]Aging Biomarker Consortium (ABC), Beijing, China. liulin@nankai.edu.cn. [198]College of Life Sciences, Nankai University, Tianjin, China. liulin@nankai.edu.cn. [199]Aging Biomarker Consortium (ABC), Beijing, China. pliu@ibp.ac.cn. [200]Institute of Biophysics, Chinese Academy of Sciences, Beijing, China. pliu@ibp.ac.cn. [201]Aging Biomarker Consortium (ABC), Beijing, China. qliu@tmu.edu.cn. [202]Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China. qliu@tmu.edu.cn. [203]Aging Biomarker Consortium (ABC), Beijing, China. liuq2012@ustc.edu.cn. [204]Hefei National Research Center for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. liuq2012@ustc.edu.cn. [205]Aging Biomarker Consortium (ABC), Beijing, China. tiemin_liu@fudan.edu.cn. [206]State Key Laboratory of Genetic Engineering, Department of Endocrinology and Metabolism, Institute of Metabolism and Integrative Biology, Human Phenome Institute and School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, China. tiemin_liu@fudan.edu.cn. [207]Aging Biomarker Consortium (ABC), Beijing, China. wenwenliu@email.sdu.edu.cn. [208]Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, China. wenwenliu@email.sdu.edu.cn. [209]Aging Biomarker Consortium (ABC), Beijing, China. liu_xingguo@gibh.ac.cn. [210]Institute of Development and Regeneration, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. liu_xingguo@gibh.ac.cn. [211]Aging Biomarker Consortium (ABC), Beijing, China. drliuyajun@mail.ccmu.edu.cn. [212]Department of Spine Surgery, Beijing Jishuitan Hospital, National Centre for Orthopaedics, Capital Medical University, Beijing, China. drliuyajun@mail.ccmu.edu.cn. [213]Aging Biomarker Consortium (ABC), Beijing, China. liuyong31279@whu.edu.cn. [214]Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Taikang Center for Life and Medical Sciences, Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China. liuyong31279@whu.edu.cn. [215]Aging Biomarker Consortium (ABC), Beijing, China. liuyh@smu.edu.cn. [216]State Key Laboratory of Multi-organ Injury Prevention and Treatment, National Clinical Research Center for Kidney Disease, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China. liuyh@smu.edu.cn. [217]Aging Biomarker Consortium (ABC), Beijing, China. liuyoushuo@csu.edu.cn. [218]Department of Geriatrics, the Second Xiangya Hospital and the Institute of Aging and Geriatrics, Central South University, Changsha, China. liuyoushuo@csu.edu.cn. [219]Aging Biomarker Consortium (ABC), Beijing, China. zhili-liu@ncu.edu.cn. [220]Department of Geriatrics, the Third Affiliated Hospital, Department of Orthopedics, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China. zhili-liu@ncu.edu.cn. [221]Aging Biomarker Consortium (ABC), Beijing, China. pumclongxiao@126.com. [222]Peking Union Medical College Hospital, Beijing, China. pumclongxiao@126.com. [223]Aging Biomarker Consortium (ABC), Beijing, China. luyao0719@163.com. [224]Clinical Research Center, the Third Xiangya Hospital, Central South University, Changsha, China. luyao0719@163.com. [225]Aging Biomarker Consortium (ABC), Beijing, China. jluo@tongji.edu.cn. [226]Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, China. jluo@tongji.edu.cn. [227]Aging Biomarker Consortium (ABC), Beijing, China. xianghangluo@csu.edu.cn. [228]Department of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, China. xianghangluo@csu.edu.cn. [229]Aging Biomarker Consortium (ABC), Beijing, China. machunhong@sdu.edu.cn. [230]Key Laboratory for Experimental Teratology of the Ministry of Education, Department of Immunology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Shandong, China. machunhong@sdu.edu.cn. [231]Aging Biomarker Consortium (ABC), Beijing, China. mashuai@ioz.ac.cn. [232]State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. mashuai@ioz.ac.cn. [233]Aging Biomarker Consortium (ABC), Beijing, China. xrma@bio.ecnu.edu.cn. [234]Institute for Aging, East China Normal University, Shanghai, China. xrma@bio.ecnu.edu.cn. [235]Aging Biomarker Consortium (ABC), Beijing, China. maojh88@zju.edu.cn. [236]Department of Nephrology, Children Hospital of Zhejiang University School of Medicine, Zhejiang, China. maojh88@zju.edu.cn. [237]Aging Biomarker Consortium (ABC), Beijing, China. zhiyong_mao@tongji.edu.cn. [238]Shanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, China. zhiyong_mao@tongji.edu.cn. [239]Aging Biomarker Consortium (ABC), Beijing, China. huangsq@ioz.ac.cn. [240]State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. huangsq@ioz.ac.cn. [241]Aging Biomarker Consortium (ABC), Beijing, China. niegj@nanoctr.cn. [242]CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, China. niegj@nanoctr.cn. [243]Aging Biomarker Consortium (ABC), Beijing, China. niuyy@lpbr.cn. [244]State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China. niuyy@lpbr.cn. [245]Aging Biomarker Consortium (ABC), Beijing, China. yaojin.peng@ioz.ac.cn. [246]State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. yaojin.peng@ioz.ac.cn. [247]Aging Biomarker Consortium (ABC), Beijing, China. pujun310@hotmail.com. [248]Division of Cardiology, State Key Laboratory of Systems Medicine for Cancer, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. pujun310@hotmail.com. [249]Aging Biomarker Consortium (ABC), Beijing, China. qijieyu@bit.edu.cn. [250]Department of Radiology, Zhuhai People's Hospital, the Affiliated Hospital of Beijing Institute of Technology, Advanced Technology Research Institute, School of Life Science, State Key Laboratory of Hearing and Balance Science, Beijing Institute of Technology, Beijing, China. qijieyu@bit.edu.cn. [251]Aging Biomarker Consortium (ABC), Beijing, China. qiang@pku.edu.cn. [252]Department of Pharmacology, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China. qiang@pku.edu.cn. [253]Aging Biomarker Consortium (ABC), Beijing, China. jie.qiao@263.net. [254]State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China. jie.qiao@263.net. [255]Aging Biomarker Consortium (ABC), Beijing, China. qinyingying@sdu.edu.cn. [256]State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, China. qinyingying@sdu.edu.cn. [257]Aging Biomarker Consortium (ABC), Beijing, China. aijuanqu@ccmu.edu.cn. [258]Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China. aijuanqu@ccmu.edu.cn. [259]Aging Biomarker Consortium (ABC), Beijing, China. qujing@ioz.ac.cn. [260]Key Laboratory of Organ Regeneration and Reconstruction, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. qujing@ioz.ac.cn. [261]Aging Biomarker Consortium (ABC), Beijing, China. renjie@big.ac.cn. [262]China National Center for Bioinformation, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China. renjie@big.ac.cn. [263]Aging Biomarker Consortium (ABC), Beijing, China. rbren@sjtu.edu.cn. [264]International Center for Aging and Cancer, Hainan Medical University, Haikou, China. rbren@sjtu.edu.cn. [265]Aging Biomarker Consortium (ABC), Beijing, China. xiongzruan@foxmail.com. [266]Centre for Lipid Research and Chongqing Key Laboratory of Metabolism on Lipid and Glucose, the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China. xiongzruan@foxmail.com. [267]Aging Biomarker Consortium (ABC), Beijing, China. ashi@hust.edu.cn. [268]Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, China. ashi@hust.edu.cn. [269]Aging Biomarker Consortium (ABC), Beijing, China. hbshi@sjtu.edu.cn. [270]Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. hbshi@sjtu.edu.cn. [271]Aging Biomarker Consortium (ABC), Beijing, China. shijie@bjmu.edu.cn. [272]National Institute on Drug Dependence, Peking University, Beijing, China. shijie@bjmu.edu.cn. [273]Aging Biomarker Consortium (ABC), Beijing, China. hrmaskf@hku.hk. [274]Key Laboratory of CNS Regeneration (Ministry of Education), Guangdong-Hong Kong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, China. hrmaskf@hku.hk. [275]Aging Biomarker Consortium (ABC), Beijing, China. songmoshi@ioz.ac.cn. [276]State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. songmoshi@ioz.ac.cn. [277]Aging Biomarker Consortium (ABC), Beijing, China. weihong@wmu.edu.cn. [278]Center for Geriatric Medicine, the First Affiliated Hospital and Oujiang Laboratory, Institute of Aging, Wenzhou Medical University, Wenzhou, China. weihong@wmu.edu.cn. [279]Aging Biomarker Consortium (ABC), Beijing, China. songyanz@mail.sysu.edu.cn. [280]MOE Key Laboratory of Gene Function and Regulation, Guangzhou Key Laboratory of Healthy Aging Research, School of Life Sciences, Institute of Healthy Aging Research, Sun Yat-sen University, Guangzhou, China. songyanz@mail.sysu.edu.cn. [281]Aging Biomarker Consortium (ABC), Beijing, China. drsujiacan@163.com. [282]Department of Orthopedic, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. drsujiacan@163.com. [283]Aging Biomarker Consortium (ABC), Beijing, China. sun.aijun@zs-hospital.sh.cn. [284]Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China. sun.aijun@zs-hospital.sh.cn. [285]Aging Biomarker Consortium (ABC), Beijing, China. sunbmu@foxmail.com. [286]The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology of National Health Commission, Beijing, China. sunbmu@foxmail.com. [287]Aging Biomarker Consortium (ABC), Beijing, China. sunq@bmi.ac.cn. [288]Laboratory of Advanced Biotechnology, Institute of Biotechnology, Academy of Military Medical Science, Research Unit of Cell Death Mechanism, 2021RU008, Chinese Academy of Medical Science, Beijing, China. sunq@bmi.ac.cn. [289]Aging Biomarker Consortium (ABC), Beijing, China. yi.eve.sun@gmail.com. [290]Stem Cell Translational Research Center, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China. yi.eve.sun@gmail.com. [291]Aging Biomarker Consortium (ABC), Beijing, China. sunyu@sinh.ac.cn. [292]Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China. sunyu@sinh.ac.cn. [293]Aging Biomarker Consortium (ABC), Beijing, China. pftang301@126.com. [294]Department of Orthopedics, the Fourth Medical Center of Chinese PLA General Hospital and National Clinical Research Center for Orthopedics, Sports Medicine and Rehabilitation, Beijing, China. pftang301@126.com. [295]Aging Biomarker Consortium (ABC), Beijing, China. qqtang@shmu.edu.cn. [296]Key Lab of Metabolism and Molecular Medicine (MOE), Department of Biochemistry and Molecular Biology, Fudan University School of Basic Medical Sciences, Shanghai, China. qqtang@shmu.edu.cn. [297]Aging Biomarker Consortium (ABC), Beijing, China. tangyi@xwhosp.org. [298]Department of Neurology and Innovation Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, National Center for Neurological Disorders, Beijing, China. tangyi@xwhosp.org. [299]Aging Biomarker Consortium (ABC), Beijing, China. taojungz123@163.com. [300]Department of Hypertension and Vascular Disease, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. taojungz123@163.com. [301]Aging Biomarker Consortium (ABC), Beijing, China. lingtaofmmu@qq.com. [302]Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China. lingtaofmmu@qq.com. [303]Aging Biomarker Consortium (ABC), Beijing, China. tianmei@fudan.edu.cn. [304]Human Phenome Institute, Fudan University, Shanghai, China. tianmei@fudan.edu.cn. [305]Aging Biomarker Consortium (ABC), Beijing, China. tianxiaoli@ncu.edu.cn. [306]Human Aging Research Institute and School of Life Science, Nanchang University and Jiangxi Province Key Laboratory of Aging and Disease, Nanchang, China. tianxiaoli@ncu.edu.cn. [307]Aging Biomarker Consortium (ABC), Beijing, China. ytian@genetics.ac.cn. [308]Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China. ytian@genetics.ac.cn. [309]Aging Biomarker Consortium (ABC), Beijing, China. tongxiaolin@vip.163.com. [310]Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. tongxiaolin@vip.163.com. [311]Aging Biomarker Consortium (ABC), Beijing, China. wangcy@tjh.tjmu.edu.cn. [312]Shanxi Bethune Hospital, Shanxi Academy of Medical Science, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, the Key Laboratory of Endocrine and Metabolic Diseases of Shanxi Province, Shanxi, China. wangcy@tjh.tjmu.edu.cn. [313]Aging Biomarker Consortium (ABC), Beijing, China. whboto11@email.sdu.edu.cn. [314]Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, China. whboto11@email.sdu.edu.cn. [315]Aging Biomarker Consortium (ABC), Beijing, China. wanghm@ioz.ac.cn. [316]State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. wanghm@ioz.ac.cn. [317]Aging Biomarker Consortium (ABC), Beijing, China. huating.wang@cuhk.edu.hk. [318]Department of Orthopaedics and Traumatology, Li Ka Shing Institute of Health Sciences, InnoHK Center for Neuromusculoskeletal Restorative Medicine, the Chinese University of Hong Kong, Hong Kong, China. huating.wang@cuhk.edu.hk. [319]Aging Biomarker Consortium (ABC), Beijing, China. wangjianan111@zju.edu.cn. [320]Department of Cardiology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. wangjianan111@zju.edu.cn. [321]Aging Biomarker Consortium (ABC), Beijing, China. wangjw28@163.com. [322]Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. wangjw28@163.com. [323]Aging Biomarker Consortium (ABC), Beijing, China. wangjianwei@ihcams.ac.cn. [324]State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. wangjianwei@ihcams.ac.cn. [325]Aging Biomarker Consortium (ABC), Beijing, China. wangjq@shsmu.edu.cn. [326]Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. wangjq@shsmu.edu.cn. [327]Aging Biomarker Consortium (ABC), Beijing, China. lihengwang@hsc.pku.edu.cn. [328]Institute of Cardiovascular Sciences, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China. lihengwang@hsc.pku.edu.cn. [329]Aging Biomarker Consortium (ABC), Beijing, China. fierywang@163.com. [330]Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China. fierywang@163.com. [331]Aging Biomarker Consortium (ABC), Beijing, China. miao.wang@pumc.edu.cn. [332]State Key Laboratory of Cardiovascular Disease, NHC Key Laboratory of Clinical Research for Cardiovascular Medications, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. miao.wang@pumc.edu.cn. [333]Aging Biomarker Consortium (ABC), Beijing, China. qiangwang@scut.edu.cn. [334]Innovation Centre of the Ministry of Education for Development and Diseases, School of Medicine, South China University of Technology, Guangzhou, China. qiangwang@scut.edu.cn. [335]Aging Biomarker Consortium (ABC), Beijing, China. wangsi@xwh.ccmu.edu.cn. [336]Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing, China. wangsi@xwh.ccmu.edu.cn. [337]Aging Biomarker Consortium (ABC), Beijing, China. wangsijia@sinh.ac.cn. [338]CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China. wangsijia@sinh.ac.cn. [339]Aging Biomarker Consortium (ABC), Beijing, China. slwang@ccmu.edu.cn. [340]Laboratory of Oral Homeostatic Medicine School of Medicine and SHMl, Southern University of Science and Technology, Shenzhen, China. slwang@ccmu.edu.cn. [341]Aging Biomarker Consortium (ABC), Beijing, China. wwg@bjmu.edu.cn. [342]Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China. wwg@bjmu.edu.cn. [343]Aging Biomarker Consortium (ABC), Beijing, China. xmwang@fmmu.edu.cn. [344]Airforce Military Medical University, Xi'an, China. xmwang@fmmu.edu.cn. [345]Aging Biomarker Consortium (ABC), Beijing, China. xnwang88@163.com. [346]School of Life Sciences, Fudan University, Shanghai, China. xnwang88@163.com. [347]Aging Biomarker Consortium (ABC), Beijing, China. Wang.y@whu.edu.cn. [348]State Key Laboratory of Metabolism and Regulation in Complex Organisms, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China. Wang.y@whu.edu.cn. [349]Aging Biomarker Consortium (ABC), Beijing, China. yanjiang_wang@tmmu.edu.cn. [350]Department of Neurology and Center for Clinical Neuroscience, Daping Hospital, Third Military Medical University, Chongqing, China. yanjiang_wang@tmmu.edu.cn. [351]Aging Biomarker Consortium (ABC), Beijing, China. wangyuan980510@163.com. [352]Key Laboratory of Remodeling-related Cardiovascular Diseases, Ministry of Education, Beijing Collaborative Innovation Centre for Cardiovascular Disorders, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. wangyuan980510@163.com. [353]Aging Biomarker Consortium (ABC), Beijing, China. wangyf008@mail.tsinghua.edu.cn. [354]Hepato-Pancreato-Biliary Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. wangyf008@mail.tsinghua.edu.cn. [355]Aging Biomarker Consortium (ABC), Beijing, China. znwang@cmu.edu.cn. [356]Department of Surgical Oncology and General Surgery, the First Hospital of China Medical University, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors (China Medical University), Ministry of Education, Shenyang, China. znwang@cmu.edu.cn. [357]Aging Biomarker Consortium (ABC), Beijing, China. xiaweiwei@scu.edu.cn. [358]Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China. xiaweiwei@scu.edu.cn. [359]Aging Biomarker Consortium (ABC), Beijing, China. wengjp@ustc.edu.cn. [360]Division of Life Sciences and Medicine, University of Science and Technology of China, the First Affiliated Hospital of Anhui Medical University, Hefei, China. wengjp@ustc.edu.cn. [361]Aging Biomarker Consortium (ABC), Beijing, China. wuht@bmi.ac.cn. [362]Beijing Institute of Basic Medical Sciences, Beijing, China. wuht@bmi.ac.cn. [363]Aging Biomarker Consortium (ABC), Beijing, China. jihongwu@fudan.edu.cn. [364]Department of Opthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China. jihongwu@fudan.edu.cn. [365]Aging Biomarker Consortium (ABC), Beijing, China. xiaohuan_xia1@163.com. [366]Department of Histology and Embryology, Tongji University School of Medicine, Shanghai, China. xiaohuan_xia1@163.com. [367]Aging Biomarker Consortium (ABC), Beijing, China. Yang.Xia1106@CSU.EDU.CN. [368]National Medical Metabolomics International Collaborative Research Center, Xiangya Hospital, Central South University, Changsha, China. Yang.Xia1106@CSU.EDU.CN. [369]Aging Biomarker Consortium (ABC), Beijing, China. xiangp@mail.sysu.edu.cn. [370]Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China. xiangp@mail.sysu.edu.cn. [371]Aging Biomarker Consortium (ABC), Beijing, China. xiaogz@sustech.edu.cn. [372]Department of Biochemistry, Homeostatic Medicine Institute, School of Medicine, Shenzhen Key Laboratory of Cell Microenvironment, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Southern University of Science and Technology, Shenzhen, China. xiaogz@sustech.edu.cn. [373]Aging Biomarker Consortium (ABC), Beijing, China. junjiexiao@shu.edu.cn. [374]Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, Joint International Research Laboratory of Biomaterials and Biotechnology in Organ Repair (Ministry of Education), School of Life Science, Shanghai University, Shanghai, China. junjiexiao@shu.edu.cn. [375]Aging Biomarker Consortium (ABC), Beijing, China. ycxiao@sibs.ac.cn. [376]CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China. ycxiao@sibs.ac.cn. [377]Aging Biomarker Consortium (ABC), Beijing, China. jimzx@scu.edu.cn. [378]Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, China. jimzx@scu.edu.cn. [379]Aging Biomarker Consortium (ABC), Beijing, China. xiezhengwei@hsc.pku.edu.cn. [380]Peking University International Cancer Institute, PKU Yunnan Baiyao International Medical Research Center, State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Peking University, Beijing, China. xiezhengwei@hsc.pku.edu.cn. [381]Aging Biomarker Consortium (ABC), Beijing, China. wxiong@ustc.edu.cn. [382]Hefei National Research Center for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. wxiong@ustc.edu.cn. [383]Aging Biomarker Consortium (ABC), Beijing, China. amxu@hku.hk. [384]State Key Laboratory of Pharmaceutical Biotechnology, the University of Hong Kong, Hong Kong, China. amxu@hku.hk. [385]Aging Biomarker Consortium (ABC), Beijing, China. xuhuawhu@163.com. [386]Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, Zhongnan Hospital, Wuhan University, Wuhan, China. xuhuawhu@163.com. [387]Aging Biomarker Consortium (ABC), Beijing, China. lyxu@bio.ecnu.edu.cn. [388]School of Life Sciences, East China Normal University, Shanghai, China. lyxu@bio.ecnu.edu.cn. [389]Aging Biomarker Consortium (ABC), Beijing, China. xuminghi@bjmu.edu.cn. [390]Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, State Key Laboratory of Vascular Homeostasis and Remodeling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Peking University, Beijing, China. xuminghi@bjmu.edu.cn. [391]Aging Biomarker Consortium (ABC), Beijing, China. yanliyingkind@aliyun.com. [392]State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China. yanliyingkind@aliyun.com. [393]Aging Biomarker Consortium (ABC), Beijing, China. doctoryjy@scu.edu.cn. [394]Liver Transplant Center, Institute of Organ Transplantation, Key Laboratory of Transplant Engineering and Immunology, NHC, West China Hospital, Sichuan University, Chengdu, China. doctoryjy@scu.edu.cn. [395]Aging Biomarker Consortium (ABC), Beijing, China. yangj@bjmu.edu.cn. [396]Department of Physiology and Pathophysiology, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Center for Non-coding RNA Medicine, Peking University Health Science Center, Beijing, China. yangj@bjmu.edu.cn. [397]Aging Biomarker Consortium (ABC), Beijing, China. yangliu@fmmu.edu.cn. [398]Department of Orthopaedics Institute, Xijing Hospital, the Fourth Military Medical University, Xi'an, China. yangliu@fmmu.edu.cn. [399]Aging Biomarker Consortium (ABC), Beijing, China. ygyang@cncb.ac.cn. [400]China National Center for Bioinformation, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China. ygyang@cncb.ac.cn. [401]Aging Biomarker Consortium (ABC), Beijing, China. yang_ze@sina.com. [402]The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology of National Health Commission, Beijing, China. yang_ze@sina.com. [403]Aging Biomarker Consortium (ABC), Beijing, China. yangzhenglin@cashq.ac.cn. [404]The Sichuan Provincial Key Laboratory for Human Disease Gene Study, the Department of Medical Genetics, the Department of Laboratory Medicine, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China. yangzhenglin@cashq.ac.cn. [405]Aging Biomarker Consortium (ABC), Beijing, China. yao_hongjie@gzlab.ac.cn. [406]Department of Basic Research, Guangzhou National Laboratory, Guangzhou, China. yao_hongjie@gzlab.ac.cn. [407]Aging Biomarker Consortium (ABC), Beijing, China. yj11254@rjh.com.cn. [408]International Laboratory in Hematology, Cancer, Aging and Hematology, P&#xf4 [410]le Sino-Fran&#xe7 [411]ais de Recherches en Sciences du Vivant et G&#xe9 [412]nomique, Department of Geriatrics, Medical Center on Aging of Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. yj11254@rjh.com.cn. [409]Aging Biomarker Consortium (ABC), Beijing, China. chengqi.yi@pku.edu.cn. [410]State Key Laboratory of Gene Function and Modulation Research, School of Life Sciences, Peking University, Beijing, China. chengqi.yi@pku.edu.cn. [411]Aging Biomarker Consortium (ABC), Beijing, China. fanyi@sdu.edu.cn. [412]Department of Pharmacology, School of Basic Medical Sciences, Shandong University, Jinan, China. fanyi@sdu.edu.cn. [413]Aging Biomarker Consortium (ABC), Beijing, China. yuhonghua@gdph.org.cn. [414]Guangdong Eye Institute, Department of Ophthalmology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China. yuhonghua@gdph.org.cn. [415]Aging Biomarker Consortium (ABC), Beijing, China. yuyang5012@hotmail.com. [416]Clinical Stem Cell Research Center, Reproductive Medical Center, Peking University Third Hospital, Beijing, China. yuyang5012@hotmail.com. [417]Aging Biomarker Consortium (ABC), Beijing, China. dryzr@pku.edu.cn. [418]Department of Orthopedics, Peking University First Hospital, Beijing, China. dryzr@pku.edu.cn. [419]Aging Biomarker Consortium (ABC), Beijing, China. ytf0707@126.com. [420]Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine and School of Psychology, Shanghai, China. ytf0707@126.com. [421]Aging Biomarker Consortium (ABC), Beijing, China. yuejirong11@hotmail.com. [422]Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, China. yuejirong11@hotmail.com. [423]Aging Biomarker Consortium (ABC), Beijing, China. ryue@tongji.edu.cn. [424]State Key Laboratory of Cardiovascular Diseases and Medical Innovation Center, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai, China. ryue@tongji.edu.cn. [425]Aging Biomarker Consortium (ABC), Beijing, China. czhang@188.com. [426]College of Basic Medicine, Inner Mongolia Medical University, Hohhot, China. czhang@188.com. [427]Aging Biomarker Consortium (ABC), Beijing, China. zhangchx999@163.com. [428]Department of Cardiology, the Affiliated Hospital of Southwest Medical University, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China. zhangchx999@163.com. [429]Aging Biomarker Consortium (ABC), Beijing, China. ctzhang0425@163.com. [430]Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ctzhang0425@163.com. [431]Aging Biomarker Consortium (ABC), Beijing, China. fengzhang@wmu.edu.cn. [432]Department of Respiratory and Critical Care, Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, China. fengzhang@wmu.edu.cn. [433]Aging Biomarker Consortium (ABC), Beijing, China. zhanghongbo@mail.sysu.edu.cn. [434]The Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China. zhanghongbo@mail.sysu.edu.cn. [435]Aging Biomarker Consortium (ABC), Beijing, China. zhanghongjia722@ccmu.edu.cn. [436]Beijing Anzhen Hospital, Capital Medical University, Beijing, China. zhanghongjia722@ccmu.edu.cn. [437]Aging Biomarker Consortium (ABC), Beijing, China. huijiezhang2005@126.com. [438]Department of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, China. huijiezhang2005@126.com. [439]Aging Biomarker Consortium (ABC), Beijing, China. jiezhang@xmu.edu.cn. [440]Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China. jiezhang@xmu.edu.cn. [441]Aging Biomarker Consortium (ABC), Beijing, China. doctorzhangjj@csu.edu.cn. [442]National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Department of Endocrinology, the Second Xiangya Hospital of Central South University, Changsha, China. doctorzhangjj@csu.edu.cn. [443]Aging Biomarker Consortium (ABC), Beijing, China. zhanglcheng218@126.com. [444]Department of Orthopedics, the Fourth Medical Center of Chinese PLA General Hospital and National Clinical Research Center for Orthopedics, Sports Medicine and Rehabilitation, Beijing, China. zhanglcheng218@126.com. [445]Aging Biomarker Consortium (ABC), Beijing, China. zhanglq@nic.bmi.ac.cn. [446]The &#x3c0 [451]-HuB Consortium, Beijing, China. zhanglq@nic.bmi.ac.cn. [447]State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China. zhanglq@nic.bmi.ac.cn. [448]Aging Biomarker Consortium (ABC), Beijing, China. zhangluoying@hust.edu.cn. [449]Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China. zhangluoying@hust.edu.cn. [450]Aging Biomarker Consortium (ABC), Beijing, China. zhangqji@mail.sysu.edu.cn. [451]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-Sen University, Guangzhou, China. zhangqji@mail.sysu.edu.cn. [452]Aging Biomarker Consortium (ABC), Beijing, China. ndyfy00266@ncu.edu.cn. [453]Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China. ndyfy00266@ncu.edu.cn. [454]Aging Biomarker Consortium (ABC), Beijing, China. wzhang@smmu.edu.cn. [455]National Key Laboratory of Immunity and Inflammation, Department of Pathophysiology, Naval Medical University, Shanghai, China. wzhang@smmu.edu.cn. [456]Aging Biomarker Consortium (ABC), Beijing, China. xinzhang0805@bjmu.edu.cn. [457]Department of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing, China. xinzhang0805@bjmu.edu.cn. [458]Aging Biomarker Consortium (ABC), Beijing, China. zhangx@bjhmoh.cn. [459]Department of Rheumatology, Beijing Hospital, National Centre of Gerontology, Institute of Geriatric Medicine, Clinical Immunology Centre, Chinese Academy of Medical Sciences, Beijing, China. zhangx@bjhmoh.cn. [460]Aging Biomarker Consortium (ABC), Beijing, China. yongzhang@ibms.pumc.edu.cn. [461]State Key Laboratory of Complex, Severe and Rare Diseases, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, China. yongzhang@ibms.pumc.edu.cn. [462]Aging Biomarker Consortium (ABC), Beijing, China. yunzhang@xmu.edu.cn. [463]Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, China. yunzhang@xmu.edu.cn. [464]Aging Biomarker Consortium (ABC), Beijing, China. zhang_rzs@bnu.edu.cn. [465]State Key Laboratory of Cognitive Neuroscience and Learning, Faculty of Psychology, Beijing Normal University, Beijing, China. zhang_rzs@bnu.edu.cn. [466]Aging Biomarker Consortium (ABC), Beijing, China. zhangzhuohua@sklmg.edu.cn. [467]Institute of Molecular Precision Medicine, Xiangya Hospital, Central South University, Changsha, China. zhangzhuohua@sklmg.edu.cn. [468]Aging Biomarker Consortium (ABC), Beijing, China. bingzhao@ncu.edu.cn. [469]School of Basic Medical Sciences, the First Affiliated Hospital of Nanchang University, Jiangxi Medical College, Nanchang University, Nanchang, China. bingzhao@ncu.edu.cn. [470]Aging Biomarker Consortium (ABC), Beijing, China. ggzhao@vip.sina.com. [471]Beijing Municipal Geriatric Medical Research Center, National Medical Center for Neurological Diseases, Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, China. ggzhao@vip.sina.com. [472]Aging Biomarker Consortium (ABC), Beijing, China. jjzhao@sdu.edu.cn. [473]Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong, China. jjzhao@sdu.edu.cn. [474]Aging Biomarker Consortium (ABC), Beijing, China. zhaom38@mail.sysu.edu.cn. [475]Key Laboratory of Stem Cells and Tissue Engineering (Ministry of Education), Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China. zhaom38@mail.sysu.edu.cn. [476]Aging Biomarker Consortium (ABC), Beijing, China. tbzhao@ioz.ac.cn. [477]State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. tbzhao@ioz.ac.cn. [478]Aging Biomarker Consortium (ABC), Beijing, China. jialinzheng@tongji.edu.cn. [479]Center for Translational Neurodegeneration and Regenerative Therapy, Tongji Hospital Affiliated to Tongji University School of Medicine, Shanghai, China. jialinzheng@tongji.edu.cn. [480]Aging Biomarker Consortium (ABC), Beijing, China. zhengjunke@shsmu.edu.cn. [481]Hongqiao International Institute of Medicine, Shanghai Tongren Hospital, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhengjunke@shsmu.edu.cn. [482]Aging Biomarker Consortium (ABC), Beijing, China. zzza00509@btch.edu.cn. [483]Department of Radiology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. zzza00509@btch.edu.cn. [484]Aging Biomarker Consortium (ABC), Beijing, China. huixia99999@163.com. [485]Department of Pediatric Urology, the Seventh Medical Center of Chinese PLA General Hospital, Beijing, China. huixia99999@163.com. [486]Aging Biomarker Consortium (ABC), Beijing, China. jinli730@smu.edu.cn. [487]National Key Laboratory for Prevention and Treatment of Multi-organ Injury, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China. jinli730@smu.edu.cn. [488]Aging Biomarker Consortium (ABC), Beijing, China. zhouxt@shsmu.edu.cn. [489]State Key Laboratory of Eye Health, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhouxt@shsmu.edu.cn. [490]Aging Biomarker Consortium (ABC), Beijing, China. kqzhouysh@hsc.pku.edu.cn. [491]Department of Prosthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology and National Health Commission Key Laboratory of Digital Technology of Stomatology, Beijing, China. kqzhouysh@hsc.pku.edu.cn. [492]Aging Biomarker Consortium (ABC), Beijing, China. zhongjun@hku.hk. [493]School of Biomedical Sciences, LKS Faculty of Medicine, the University of Hong Kong, Hong Kong, China. zhongjun@hku.hk. [494]Aging Biomarker Consortium (ABC), Beijing, China. zhu_julie@vip.sina.com. [495]Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric and Gynecologic Diseases, State Key Laboratory of Common Mechanism Research for Major Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. zhu_julie@vip.sina.com. [496]Aging Biomarker Consortium (ABC), Beijing, China. yzzhu@must.edu.mo. [497]School of Pharmacy and R&amp [503]D Centre for Drug Discovery from Natural Resources, Macau University of Science and Technology, Macau, China. yzzhu@must.edu.mo. [498]Aging Biomarker Consortium (ABC), Beijing, China. hbpcms@sina.com. [499]Department of Hypertension and Endocrinology, Daping Hospital, Army Medical University, Chongqing, China. hbpcms@sina.com. [500]Aging Biomarker Consortium (ABC), Beijing, China. zh_wenj@163.com. [501]Ningxia Eye Hospital, People's Hospital of Ningxia Hui Autonomous Region, the Third Affiliated Clinical College of Ningxia Medical University, Yinchuan, China. zh_wenj@163.com. [502]Aging Biomarker Consortium (ABC), Beijing, China. zouwg94@sibcb.ac.cn. [503]Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Beijing, China. zouwg94@sibcb.ac.cn. [504]Aging Biomarker Consortium (ABC), Beijing, China. zhangwq@big.ac.cn. [505]China National Center for Bioinformation, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China. zhangwq@big.ac.cn. [506]Aging Biomarker Consortium (ABC), Beijing, China. peigang@tongji.edu.cn. [507]The Collaborative Innovation Center for Brain Science, School of Life Sciences and Technology, Tongji University, Shanghai, China. peigang@tongji.edu.cn. [508]Aging Biomarker Consortium (ABC), Beijing, China. ghliu@ioz.ac.cn. [509]State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. ghliu@ioz.ac.cn.
出处：
DOI： 10.1038/s43587-025-00935-w

摘要：
The global surge in the population of people 60 years and older, including that in China, challenges healthcare systems with rising age-related diseases. To address this demographic change, the Aging Biomarker Consortium (ABC) has launched the X-Age Project to develop a comprehensive aging evaluation system tailored to the Chinese population. Our goal is to identify robust biomarkers and construct composite aging clocks that capture biological age, defined as an individual's physiological and molecular state, across diverse Chinese cohorts. This Perspective outlines the core objectives, methodological framework and key deliverables of the X-Age Project, including cohort recruitment, standardized sample collection, multimodal data acquisition and clock model development. By integrating interdisciplinary expertise, we aim to provide a practical and scalable platform for understanding aging complexity and heterogeneity, early detection of accelerated aging and evaluation of aging interventions.© 2025. Springer Nature America, Inc.

语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2025]版：
大类 | 1 区 医学
小类 | 1 区 细胞生物学 1 区 老年医学 1 区 神经科学
最新[2025]版：
大类 | 1 区 医学
小类 | 1 区 细胞生物学 1 区 老年医学 1 区 神经科学
第一作者：
第一作者机构： [1]Aging Biomarker Consortium (ABC), Beijing, China. [2]China National Center for Bioinformation, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
通讯作者：
通讯机构： [508]Aging Biomarker Consortium (ABC), Beijing, China. ghliu@ioz.ac.cn. [509]State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. ghliu@ioz.ac.cn.
推荐引用方式(GB/T 7714)：
Li Jiaming,Jiang Mengmeng,Wang Qiaoran,et al.The X-Age Project to construct a Chinese aging clock[J].Nature Aging.2025,5(9):1669-1685.doi:10.1038/s43587-025-00935-w.
APA：
Li Jiaming,Jiang Mengmeng,Wang Qiaoran,Zheng Zikai,Shen Jianghua...&Liu Guang-Hui.(2025).The X-Age Project to construct a Chinese aging clock.Nature Aging,5,(9)
MLA：
Li Jiaming,et al."The X-Age Project to construct a Chinese aging clock".Nature Aging 5..9(2025):1669-1685

资源点击量：29059 今日访问量：0 总访问量：1619 更新日期：2025-10-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 首都医科大学附属北京同仁医院 技术支持：重庆聚合科技有限公司 地址：北京市东城区东交民巷1号(100730)