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Causes of In-Hospital Death in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention in Beijing Area

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机构: [1]Department of Geriatrics, Xuanwu Hospital Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing 100053, China. [2]Division of Cardiology, Chui Yang Liu Hospital affiliated to Tsinghua University, Beijing 100022, China. [3]Beijing Quality Control and Improvement Center for Cardiovascular Intervention, Beijing 100037, China. [4]Division of Cardiology, Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing 100029, China. [5]Division of Cardiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China. [6]Division of Cardiology, Aviation General Hospital, Chinese Medical University, Beijing 100012, China. [7]Division of Cardiology, Peking University Third Hospital, Beijing 100191, China. [8]Division of Cardiology, Xuanwu Hospital Capital Medical University, Beijing 100053, China. [9]Division of Cardiology, Civil Aviation General Hospital, Beijing 100123, China. [10]Division of Cardiology, Beijing Hospital of Traditional Chinese Medicine, Beijing 100010, China. [11]Division of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China. [12]Division of Cardiology, Peking Union Medical College Hospital, Beijing 100730, China. [13]Division of Cardiology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China. [14]Division of Cardiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China. [15]Division of Cardiology, Fuwai Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100037, China. [16]Division of Geriatrics, Peking University Third Hospital, Beijing 100191, China. [17]Division of Cardiology, Beijing Jishuitan Hospital, Beijing 100035, China. [18]Division of Cardiology, Fuwai Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100037, China. Electronic address: yangyjfw@126.com.
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This study aimed to identify causes of in-hospital death in ST-segment elevation myocardial infarction (STEMI) patients undergoing percutaneous coronary intervention (PPCI) in the Bejing metropolitan area.A total of 56,763 PPCIs were performed at 56 eligible hospitals between January 1, 2010, and December 31, 2018, among which 1,278 patients died. Causes of death were analyzed and finally adjudicated by a review board. The overall in-hospital mortality rate was 2.25%, ranging annually from 1.96% to 2.48% over the study period. Of these, 1069 (83.6%) deaths were attributed to disease severity-related causes, mainly cardiogenic shock of 44.4%, mechanical complications of 15.2%, malignant arrhythmia of 8.1% and heart failure of 6.2%. Another 209 (16.4%) patients died from PPCI-related complications, including coronary no-reflow of 8.5%, stent thrombosis of 3.5%, and PPCI-related bleeding of 2.4%. The incidence of PPCI-related death has decreased from 1.02% in 2010 to 0.15% in 2018 (P<.001). Hospitals in the highest quartile PPCI volume (>130 PPCI annually) had lower incidence of in-hospital death (1.97% vs. 2.62%, 2.99% and 2.56%, P<.001), disease severity-related death (1.66% vs. 2.13%, 2.4% and 2.17%, P<.001) and PPCI-related death (0.31% vs. 0.48%, 0.59% and 0.39%, P=.003), as compared to those with the first, second and third quartiles of annual PPCI volume. In conclusion,among patients with STEMI and treated with PPCI, in-hospital mortality keeps at a relatively low level in Beijing area. Most deaths are due to pathophysiological deteriorations following STEMI. Hospital PPCI volume remains serve as an important indicator for quality of care.Copyright © 2025. Published by Elsevier Inc.

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大类 | 3 区 医学
小类 | 4 区 心脏和心血管系统
最新[2025]版:
大类 | 3 区 医学
小类 | 4 区 心脏和心血管系统
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第一作者机构: [1]Department of Geriatrics, Xuanwu Hospital Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing 100053, China.
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