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Controversies, Consensuses and Guidelines on Etiology, Diagnosis, Treatment, and Future Developments of Neovascular Age-Related Macular Degeneration (nAMD) by the Asia-Pacific Vitreo-retina Society (APVRS), the Asia-Pacific Ocular Imaging Society (APOIS) and the Academy of the Asia-Pacific Professors of Ophthalmology (AAPPO)

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机构： [1]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China [2]Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan [3]Department of Ophthalmology, National Taiwan University Hospital, Taipei City, Taiwan [4]Department of Ophthalmology, College of Medicine, National Taiwan University, Taipei City, Taiwan [5]Department of Ophthalmology, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan [6]John F. Hardesty, MD, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine in St. Louis, St. Louis, MO, USA [7]Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA [8]Department of Developmental Biology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA [9]Shri Bhagwan Mahavir Vitreoretinal Services, Chennai, Tamil Nadu, India [10]Sydney Retina Clinic, Sydney Eye Hospital, University of Sydney, Sydney, NSW, Australia [11]Department of Ophthalmology, Retina Division, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand [12]Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, China and Key Lab of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing, China [13]Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, China [14]Hong Kong Hub of Paediatric Excellence, The Chinese University of Hong Kong, Hong Kong, China [15]Medical Retina, Ophthalmology, Singapore National Eye Centre, Singapore, Singapore [16]Ophthalmology & Visual Sciences Academic Clinical Program, SingHealth Duke-NUS, Singapore, Singapore [17]Singapore Eye Research Institute, Singapore [18]Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA [19]Department of Ophthalmology, Oasis Eye Specialists, Kuala Lumpur, Malaysia [20]Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia [21]Ophthalmology, Department of Surgery, The University of Melbourne, Melbourne, Australia [22]Department of Ophthalmology, Hyogo Medical University, Nishinomiya, Japan [23]Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore [24]Retina Center of Ohio, Cleveland, OH, USA [25]Bascom Palmer Eye Institute, University of Miami, Coral Gables, FL, USA [26]Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX, USA [27]Division of Ophthalmology, Department of Surgery, University of Hawaii School of Medicine, Honolulu, HI, USA [28]Eye & Retina Surgeons, Camden Medical Centre, Singapore [29]Xiamen Research Center for Eye Diseases and Key Laboratory of Ophthalmology, Xiamen, Fujian, China [30]Xiamen Key Laboratory of Corneal & Ocular Surface Diseases, Xiamen, Fujian, China [31]Translational Medicine Institute of Xiamen Eye Center of Xiamen University, Xiamen, Fujian, China [32]Eye Institute and Affiliated Xiamen Eye Center of Xiamen University, Xiamen, China [33]University of Illinois Chicago, Chicago, IL, USA [34]The Primasia International Eye Research Institute (PIERI) of The Chinese University of Hong Kong (Shenzhen), Shenzhen, China [35]Eye Department, C+ Health CKJ (Shenzhen) Hospital, Luohu, Shenzhen, China [36]Doheny Eye Institute, Pasadena, CA, USA [37]Department of Ophthalmology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA [38]Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan [39]Department of Ophthalmology, Tokyo Medical Center, Tokyo, Japan [40]Institute of Ophthalmology, University College London, London, United Kingdom [41]National Institute for Health Research Biomedical Research Centre, Moorfields Eye Hospital National Health Service Foundation Trust, London, United Kingdom [42]Vitreoretinal and Oncology Services, Sankara Eye Hospital, Bengaluru, Karnataka, India [43]Retina Services, Centre for Sight, New Delhi, India [44]Beijing Visual Science and Translational Eye Research Institute (BERI), Beijing Tsinghua Changgung Hospital Eye Center, Tsinghua Medicine, Tsinghua University, Beijing, China [45]School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua Medicine, Tsinghua University, Beijing, China [46]Beijing Key Laboratory of Intelligent Diagnostic Technology and Devices for Major Blinding Eye Diseases, Tsinghua Medicine, Tsinghua University, Beijing, China [47]Singapore National Eye Center, Singapore [48]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China [49]Beijing Retinal and Choroidal Vascular Diseases Study Group, Beijing Tongren Hospital, Beijing, China [50]The C-MER Dennis Lam and Partners Eye Center, C-MER International Eye Care Group, Hong Kong, China

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关键词： Controversy Consensus Guidelines Neovascular age-related macular degeneration Etiology Diagnosis Treatment

摘要：

Neovascular age-related degeneration (nAMD) is one of the leading causes of visual impairment in older populations in the developed world. With the aging population, the incidence of nAMD is growing globally. Despite advancements in diagnostic investigations and treatment modalities over the past three decades, there remains considerable controversies in the pathogenesis, classification and optimal management strategies. An international panel of 35 experts from 13 countries/regions prepared and voted on consensus statements in five key areas: 1) etiology controversies; 2) diagnosis controversies; 3) treatment controversies; 4) future development controversies; and 5) healthcare deliveries controversies. Among the 31 consensus statements, 28 (90.3%) have achieved over 75% agreement. These statements can provide a practical guide for ophthalmologists to provide the optimal care of patients with nAMD and for planning future research priorities in order to address the unmet needs in nAMD.Copyright © 2025. Published by Elsevier Inc.

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出版当年[2025]版：

大类 | 2 区医学

小类 | 2 区眼科学

最新[2025]版：

大类 | 2 区医学

小类 | 2 区眼科学

第一作者：

第一作者机构： [1]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China

通讯作者：

通讯机构： [1]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China [34]The Primasia International Eye Research Institute (PIERI) of The Chinese University of Hong Kong (Shenzhen), Shenzhen, China [35]Eye Department, C+ Health CKJ (Shenzhen) Hospital, Luohu, Shenzhen, China [50]The C-MER Dennis Lam and Partners Eye Center, C-MER International Eye Care Group, Hong Kong, China

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