详情页 - 首都医科大学附属北京同仁医院知识库

当前位置：首页 > 详情页

Non-invasive low-level red-light therapy for axial length control in pediatric extreme myopia

文献详情

资源类型：

Pubmed体系：

作者：

机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China. [2]Department of Biostatistics, School of Public Health, Peking University, Beijing, China. [3]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China. [4]Institute of Science Tokyo, Tokyo, Japan.

出处：

DOI：

摘要：

Extreme myopia presents a notable clinical challenge in management, with existing approaches having limitations. Repeated low-level red-light therapy (RLRL) has shown potential for myopia control. This multi-center prospective study included 59 children (101 eyes, aged 3-16.3 years) with extreme (SER ≤ -10D) or high myopia (-6D to -9.75D), who underwent twice-daily RLRL for 12 months 55 children (94 eyes) completed the follow-up. After treatment, significant improvements were observed: spherical equivalent error increased by 0.549D (95% confidence interval [CI]: 0.430 to 0.668, p < 0.001), axial length shortened by 0.056 mm (95% CI: -0.087 to -0.025, p = 0.001), best-corrected visual acuity improved by 0.110 LogMAR, and choroidal thickness increased by 34.84 μm, with no adverse events. Subgroup analysis found comparable efficacy between the extreme and high myopia groups. These results indicate RLRL is a safe, non-invasive option for managing extreme myopia in children, with meaningful clinical value.© 2025 Published by Elsevier Inc.

基金：

语种：

PubmedID：

中科院(CAS)分区：

出版当年[2025]版：

大类 | 2 区综合性期刊

小类 | 2 区综合性期刊

最新[2025]版：

大类 | 2 区综合性期刊

小类 | 2 区综合性期刊

第一作者：

第一作者机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

共同第一作者：

通讯作者：

通讯机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China. [3]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

推荐引用方式(GB/T 7714)：

APA：

MLA：