机构：[1]Department of Otolaryngology, Catholic University of Córdoba, Córdoba, Argentina.[2]Department of Pediatrics, Nippon Medical School, Tokyo, Japan.[3]Department of Allergy and Immunology, Hospital Quirón Bizkaia, Erandio, Spain.[4]Department of Pediatric Respiratory Medicine, Regional Eastern Clinic, San Francisco, Córdoba, Argentina.[5]CIMER, Catholic University of Córdoba and Croce Institute, Córdoba, Argentina.[6]Pediatric Allergy Unit, Children’s Hospital, Ain Shams University, Cairo, Egypt.[7]Department of Pediatrics, National Sagamihara Hospital, Sagamihara-shi, Kanagawa, Japan.[8]Federal University of Parana, Curitiba, Brazil.[9]Allergy and Clinical Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela.[10]Department of Otolaryngology – Head and Neck Surgery, Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.临床科室耳鼻咽喉-头颈外科变态反应科研究所耳鼻咽喉科研究所首都医科大学附属北京同仁医院首都医科大学附属同仁医院
Otitis Media with Effusion (OME) is an inflammatory condition of the middle ear cleft, acute or chronic, with collection of fluid in the middle ear with an intact tympanic membrane. It is a very common disease in childhood, the most frequent cause of hearing loss in childhood and often requiring surgery. OME is called chronic when the fluid in the middle ear persists for more than three months or when the episodes recur six or more times in one year. The current article covers various aspects of OME including definition, epidemiology. Pathomechanisms, risk factors, role of allergy in OME, impact of upper airway disease on OME, eosinophilic otitis media and management of OME.
第一作者机构：[1]Department of Otolaryngology, Catholic University of Córdoba, Córdoba, Argentina.
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推荐引用方式(GB/T 7714)：
Zernotti Mario E.,Pawankar Ruby,Ansotegui Ignacio,et al.Otitis media with effusion and atopy: is there a causal relationship?[J].WORLD ALLERGY ORGANIZATION JOURNAL.2017,10:doi:10.1186/s40413-017-0168-x.
APA：
Zernotti, Mario E.,Pawankar, Ruby,Ansotegui, Ignacio,Badellino, Hector,Sebastian Croce, Juan...&Zhang, Luo.(2017).Otitis media with effusion and atopy: is there a causal relationship?.WORLD ALLERGY ORGANIZATION JOURNAL,10,
MLA：
Zernotti, Mario E.,et al."Otitis media with effusion and atopy: is there a causal relationship?".WORLD ALLERGY ORGANIZATION JOURNAL 10.(2017)
