Purpose: To investigate the effects of congenital, peripheral and central fourth nerve palsies on vertical saccades.
Methods: Seven patients with unilateral congenital fourth nerve palsy, one with unilateral chronic peripheral fourth nerve palsy caused by a skull base clivus chordoma, . and one with unilateral central palsy caused by a lesion in the midbrain were studied. Ten normal subjects served as controls. All patients underwent MR imaging. Palsy under 1 month in duration was designated as acute and those of longer duration were chronic. Subjects made 20 deg vertical saccades while wearing search coils. The vertical saccades were elicited from three different horizontal positions (left 20°, midline, and right 20°). The patient with acute central palsy was retested after 3 and 6 months. Amplitude gains, peak velocities and durations of vertical saccades were analyzed.
基金:
Canadian Institutes of Health Research (CIHR)Canadian Institutes of Health Research (CIHR) [MOP 57853]
第一作者机构:[1]Beijing Tongren Hosp, Ophthalmol, Beijing, Peoples R China
推荐引用方式(GB/T 7714):
Fu T.,Blakeman A.,Chandrakumar M.,et al.Saccade Dynamics in Peripheral vs Central Fourth Nerve Palsies[J].INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE.2010,51(13):
APA:
Fu, T.,Blakeman, A.,Chandrakumar, M.,Goltz, H.&Wong, A. M. F..(2010).Saccade Dynamics in Peripheral vs Central Fourth Nerve Palsies.INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,51,(13)
MLA:
Fu, T.,et al."Saccade Dynamics in Peripheral vs Central Fourth Nerve Palsies".INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 51..13(2010)