机构：[1]Department of Ophthalmology, Peking University People's Hospital, Beijing 100044, China.[2]Eye diseases and Optometry Institute, Beijing 100044, China.[3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China.[4]College of Optometry, Peking University Health Science Center, Beijing 100044, China.[5]Clinical College of Ophthalmology, Tianjin Medical University, Tianjin 300020, China.[6]Tianjin Eye Hospital, Tianjin 300020, China.[7]Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin 300020, China.[8]Tianjin Eye Institute, Tianjin 300020, China.[9]Department of Ophthalmology, Beijing Capital International Airport Hospital, Beijing 100621, China.[10]Eye Hospital, China Academy of Chinese Medical Sciences, Beijing 100040, China.
To describe the involution patterns of vessel growth of retina through fluorescein angiography (FA) of children, who had been under treatment up to 1y previously intravitreal ranibizumab (IVR) as monotherapy for retinopathy of prematurity (ROP).This is a retrospective study. The medical information and FA of 17 children (34 eyes) whose area of avascular retina from the ora serrata was more than two disc diameters (DD) were analyzed.Among 34 eyes, all were the presence of finger-shaped vessels and arteriolar-venular shunts (100%, 34/34 eyes). Popcorn abnormalities were found in most of the eyes (94.1%, 32/34 eyes). Furthermore, in many cases (23.5%, 8/34 eyes), there were leakage persisting in the region of the junction between avascular and vascular retina. In contrast, just 2 eyes (5.9%) showed damage of retinal capillary bed and 3 eyes (8.8%) showed large area of retinal pigment epithelium (RPE) atrophy.Although IVR can be very effective in ROP, we should remain cautious as infants may remain avascular peripheral retinas and abnormal vessel. FA allows accurate visualization of vessel abnormalities in eyes with ROP, which will be helpful to affect assessment of disease activity and therapeutic effect.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2018]版：
大类|4 区医学
小类|4 区眼科学
最新[2025]版：
大类|4 区医学
小类|3 区眼科学
第一作者：
第一作者机构：[1]Department of Ophthalmology, Peking University People's Hospital, Beijing 100044, China.[2]Eye diseases and Optometry Institute, Beijing 100044, China.[3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China.[4]College of Optometry, Peking University Health Science Center, Beijing 100044, China.
共同第一作者：
通讯作者：
通讯机构：[1]Department of Ophthalmology, Peking University People's Hospital, Beijing 100044, China.[2]Eye diseases and Optometry Institute, Beijing 100044, China.[3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China.[4]College of Optometry, Peking University Health Science Center, Beijing 100044, China.[*1]Department of Ophthalmology, Peking University People's Hospital, Beijing, China[*2]Eye diseases and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Beijing, China[*3]Ophthalmology Department of Peking University People's Hospital, No.l 1 of Xizhimen South Avenue, Xicheng District, Beijing 100044, China
推荐引用方式(GB/T 7714)：
Cheng Yong,Liu Tie-Gang,Li Wei-Yi,et al.Fluorescein angiography of retinal vascular involution after intravitreal injection of ranibizumab for retinopathy of prematurity.[J].International Journal of Ophthalmology.2019,12(1):79-82.doi:10.18240/ijo.2019.01.12.
APA：
Cheng Yong,Liu Tie-Gang,Li Wei-Yi,Zhao Ming-Wei&Liang Jian-Hong.(2019).Fluorescein angiography of retinal vascular involution after intravitreal injection of ranibizumab for retinopathy of prematurity..International Journal of Ophthalmology,12,(1)
MLA：
Cheng Yong,et al."Fluorescein angiography of retinal vascular involution after intravitreal injection of ranibizumab for retinopathy of prematurity.".International Journal of Ophthalmology 12..1(2019):79-82
