机构：[1]Department of Ophthalmology, Tong Ren Hospital, The Capital University of Medical Sciences, Beijing 100730, China.首都医科大学附属同仁医院
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摘要：
To investigate the therapeutic action of synthetic interleukin-1 blockers on uveitis in rats.Experiments were performed on 18 Spraque-Dawley rats (36 eyes), and the retinal interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) were quantified by an enzyme-linked immunoabsorbent assay (ELISA) before and after the rats with uveitis treated by synthetic interleukin-1 blockers.The retinal IL-1 beta and TNF-alpha in rats with uveitis treated by synthetic IL-1 blockers (CK-138, 139) were significantly decreased than those treated by contrasting design.Synthetic IL-1 blockers (CK-138, 139) are effective in treatment of IL-1 alpha induced uveitis in the rat.
语种：
中文
PubmedID：
第一作者：
第一作者机构：[1]Department of Ophthalmology, Tong Ren Hospital, The Capital University of Medical Sciences, Beijing 100730, China.
推荐引用方式(GB/T 7714)：
Zhou Y,Li Z,An W,等.Effects of synthetic interleukin-1 blockers on uveitis in rats[J].Chinese Journal of Ophthalmology.2000,36(1):62-4.
