Factors for postoperative recurrence of orbital solitary fibrous tumor: an analysis of long-term clinical follow-up results from a Chinese tertiary hospital
机构:[1]China Capital Med Univ, Dept Neurosurg, Tongren Hosp, Chongwenmennei St, Beijing 100730, Peoples R China首都医科大学附属同仁医院[2]China Capital Med Univ, Dept Ophthalmol, Tongren Hosp, Beijing 100730, Peoples R China首都医科大学附属同仁医院[3]China Capital Med Univ, Dept Pathol, Tongren Hosp, Beijing 100730, Peoples R China首都医科大学附属同仁医院
BackgroundThis study analyzed the clinical features, imaging manifestations, histopathology, immunohistochemistry, and surgical approaches of the orbital solitary fibrous tumor (OSFT), as well as the factors for postoperative recurrence of such disease.MethodsThe clinical data of 16 patients with OSFT treated in our center from 2003 to 2020 were analyzed retrospectively, and the clinical symptoms, treatment methods, and follow-up results were recorded.ResultsOf the 16 patients, 8 were females (50.0%) and 8 were males (50.0%); the average age of treatment was 377 years and the median follow-up time was 74 (8, 228) months. Sixteen patients with OSFT underwent a total of 29 operations, of which 12 were transorbital approach operations and 17 were transfronto-orbital approach operations. Ten patients (10/16, 62.5%) had recurrence. The recurrence rate of transorbital approach operations was 83.3% (10/12), and the recurrence rate of transfronto-orbital approach operations was 17.6% (3/17). No patients had treatment-related complications.Conclusions The main pathological feature of OSFT is a benign tumor. OSFT has a tendency to grow toward the cranio-orbital junction. The postoperative recurrence rate of OSFT is relatively high, so complete tumor resection is very important for prognosis. Inappropriate surgical approaches can lead to incomplete removal of the tumor and cause recurrence. Choosing the correct operation approach according to the position of the OSFT in the orbit and complete removal of the dura mater and bone affected by the tumor is crucial for the prognosis. Nevertheless, regular long-term follow-up after complete resection is necessary.
第一作者机构:[1]China Capital Med Univ, Dept Neurosurg, Tongren Hosp, Chongwenmennei St, Beijing 100730, Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Yang Peng,Liu Hao-Cheng,Qiu E.,et al.Factors for postoperative recurrence of orbital solitary fibrous tumor: an analysis of long-term clinical follow-up results from a Chinese tertiary hospital[J].BMC OPHTHALMOLOGY.2021,21(1):doi:10.1186/s12886-021-01825-6.
APA:
Yang, Peng,Liu, Hao-Cheng,Qiu, E.,Wang, Wei,Zhang, Jia-Liang...&Kang, Jun.(2021).Factors for postoperative recurrence of orbital solitary fibrous tumor: an analysis of long-term clinical follow-up results from a Chinese tertiary hospital.BMC OPHTHALMOLOGY,21,(1)
MLA:
Yang, Peng,et al."Factors for postoperative recurrence of orbital solitary fibrous tumor: an analysis of long-term clinical follow-up results from a Chinese tertiary hospital".BMC OPHTHALMOLOGY 21..1(2021)