The frequency of CRTH2(+)Tregs in patients with asthma, especially allergic phenotype is higher compared to healthy controls and shows a negative correlation with ACT scores and PEFR. CRTH2(+)Tregs increase during exacerbation and decrease after asthma control. In vitro investigations demonstrate that Tregs of allergic patients with asthma display Th2-biased character. Abbreviation: CRTH2, chemoattractant receptor-homologous molecule expressed on Th2 cells; Tregs, regulatory T cells; ACT, asthma control test; PEFR, peak expiratory flow rate.
基金:
Phramongkutklao Hospital and Phramongkutklao College of Medicine foundation Scholarship; Christine Kuhne-Center for Allergy Research and Education (CK-CARE)
通讯机构:[1]Phramongkutklao Hosp, Dept Med, Div Allergy & Clin Immunol, Bangkok, Thailand[7]Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland[8]Christine Kuhne Ctr Allergy Res & Educ CK CARE, Davos, Switzerland[*1]Division of Allergy and Clinical Immunology, Department of Medicine, Phramongkutklao Hospital, Bangkok, Thailand
推荐引用方式(GB/T 7714):
Chantveerawong Teerapol,Sangkangjanavanich Sasipa,Chiewchalermsri Chirawat,et al.Increased circulating CRTH2(+)Tregs are associated with asthma control and exacerbation[J].ALLERGY.2022,77(2):681-685.doi:10.1111/all.15145.
APA:
Chantveerawong, Teerapol,Sangkangjanavanich, Sasipa,Chiewchalermsri, Chirawat,Pradubpongsa, Panitan,Mitthamsiri, Wat...&Boonpiyathad, Tadech.(2022).Increased circulating CRTH2(+)Tregs are associated with asthma control and exacerbation.ALLERGY,77,(2)
MLA:
Chantveerawong, Teerapol,et al."Increased circulating CRTH2(+)Tregs are associated with asthma control and exacerbation".ALLERGY 77..2(2022):681-685