机构：[1]Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland,[2]Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland,[3]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China,首都医科大学附属北京同仁医院首都医科大学附属同仁医院[4]SITEM Center for Translational Medicine and Biomedical Entrepreneurship, University of Bern, Bern, Switzerland,[5]Department of Ophthalmology, University Hospital Essen, University Duisburg-Essen, Essen, Germany,[6]Pallas Klinik, Olten, Switzerland
PurposeTo compare indocyanine green angiography (ICGA) and swept-source wide-field optical coherence tomography angiography (SS-OCTA) for the assessment of patients with posterior uveitis. MethodSS-OCTA montage images of 5 x 12 x 12 mm or 2 x 15 x 9 mm, covering ~70-90 degree of the retina of consecutive patients with posterior uveitis were acquired. The choriocapillaries and choroidal slabs were compared to findings on ICGA. ResultsSixty-eight eyes of 41 patients were included (mean age 47.2 +/- 20.4 years; 58.5% female). In 23 (34%) lesions were visible on OCTA, but not discernable on ICGA. In turn, out of the 45 eyes with clearly discernable lesions on ICGA, 22 (49%) and 21 (47%) eyes showed no corresponding areas of flow deficit on OCTA in the CC and choroidal slab, respectively. Lesion size strongly correlated among ICGA and OCTA choriocapillaries- (CC) (r = 0.99, p <= 0.0001) and choroidal slabs (r = 0.99, p <= 0.0001), respectively. The mean lesion size on the late frames of ICGA (8.45 +/- 5.47 mm(2)) was larger compared to the lesion size on OCTA CC scan (7.98 +/- 5.47 mm(2), p <= 0.0001) and choroidal scan (7.69 +/- 5.10 mm(2), p = 0.002), respectively. The lesion size on OCTA CC scan was significantly larger than on the OCTA choroidal scan (p <= 0.0001). ConclusionSS-wide field OCTA may be a promising tool to assess posterior uveitis patients and may replace ICGA to a certain extent in the future.
第一作者机构：[1]Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland,[2]Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland,[3]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China,
通讯作者：
通讯机构：[1]Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland,[2]Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland,
推荐引用方式(GB/T 7714)：
Tian Meng,Zeng Guodong,Tappeiner Christoph,et al.Comparison of Indocyanine Green Angiography and Swept-Source Wide-Field Optical Coherence Tomography Angiography in Posterior Uveitis[J].FRONTIERS IN MEDICINE.2022,9:doi:10.3389/fmed.2022.853315.
APA：
Tian, Meng,Zeng, Guodong,Tappeiner, Christoph,Zinkernagel, Martin S.,Wolf, Sebastian&Munk, Marion R..(2022).Comparison of Indocyanine Green Angiography and Swept-Source Wide-Field Optical Coherence Tomography Angiography in Posterior Uveitis.FRONTIERS IN MEDICINE,9,
MLA：
Tian, Meng,et al."Comparison of Indocyanine Green Angiography and Swept-Source Wide-Field Optical Coherence Tomography Angiography in Posterior Uveitis".FRONTIERS IN MEDICINE 9.(2022)
