详情页 - 首都医科大学附属北京同仁医院知识库

当前位置：首页 > 详情页

Case series: pachychoroid pigment epitheliopathy transformed to polypoidal choroidal vasculopathy after long-term follow-up.

文献详情

资源类型：

Pubmed体系：

作者：

机构： [1]Department of Ophthalmology, Peking University People’s Hospital, No.11 Xizhimen South Street, Beijing 100044, China. [2]Eye Diseases and Optometry Institute, Beijing, China. [3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China. [4]College of Optometry, Peking University Health Science Center, Beijing, China.

出处：

DOI：

关键词： Pachychoroid Pachychoroid pigment epitheliopathy Polypoidal choroidal vasculopathy Pachychoroid spectrum diseases

摘要：

Pachychoroid pigment epitheliopathy (PPE), a retinal disorder that falls into the pachychoroid spectrum, is characterized by retinal pigment epithelium changes in pachychoroid eyes without existing or previous subretinal fluid or soft drusen. Previous reports have indicated that PPE may share some pathophysiologic component with other pachychoroid spectrum diseases and could transform into central serous chorioretinopathy (CSC) during follow-up. CSC transformation to PNV and PCV has also been reported, but PPE transformation to PCV has not been reported. CASE PRESENTATION: Seven eyes of seven patients (four male three female, aged 62.7 ± 8.4 years) who presented with PPE at baseline transformed to PCV during follow-up. All study eyes had baseline contralateral eye diagnoses of PCV. All PPE eyes reported no symptoms at baseline and were followed up regularly for the treatment of their contralateral eyes. All PPE presented as pigment epithelium detachment (PED) at baseline. The mean central macular thickness (CMT) was 217.6 ± 14.6 µm, the mean subfoveal choroidal thickness (SFCT) was 354.9 ± 94.9 µm, and the mean sub-PPE choroidal thickness was 332.3 ± 84.6 µm. The mean PPE width and height were 1326.4 ± 791.4 µm and 58.7 ± 23.6 µm, respectively, at baseline. Disruption of the ellipsoid zone (EZ) was noted in 3 eyes, while choroidal vascular hyperpermeability (CVH) was noted in 5 eyes at baseline. The follow-up period was 75.0 ± 41.1 months, and the mean transformation time was 49.6 ± 24.8 months. All study eyes received no intervention before transformation.PPE could transform to PCV after a long follow-up period. Regular follow-ups for a long time should be recommended for patients with PPE.© 2022. The Author(s).

基金：

语种：

PubmedID：

中科院(CAS)分区：

出版当年[2021]版：

大类 | 4 区医学

小类 | 4 区眼科学

最新[2023]版：

大类 | 4 区医学

小类 | 3 区眼科学

第一作者：

第一作者机构： [1]Department of Ophthalmology, Peking University People’s Hospital, No.11 Xizhimen South Street, Beijing 100044, China. [2]Eye Diseases and Optometry Institute, Beijing, China. [3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China. [4]College of Optometry, Peking University Health Science Center, Beijing, China.

通讯作者：

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]POLYPOIDAL CHOROIDAL VASCULOPATHY UPON OPTICAL COHERENCE TOMOGRAPHIC ANGIOGRAPHY [2]息肉状脉络膜血管病变 [3]SENSITIVITY AND SPECIFICITY OF MULTISPECTRAL IMAGING FOR POLYPOIDAL CHOROIDAL VASCULOPATHY [4]OPTICAL COHERENCE TOMOGRAPHIC ENHANCED DEPTH IMAGING OF POLYPOIDAL CHOROIDAL VASCULOPATHY [5]Noninvasive multimodal imaging in diagnosing polypoidal choroidal vasculopathy [6]Polypoidal Choroidal Vasculopathy: Updates on Risk Factors, Diagnosis, and Treatments [7]Polypoidal Choroidal Vasculopathy in Adult Chinese: The Beijing Eye Study [8]Conversion of central serous chorioretinopathy to polypoidal choroidal vasculopathy [9]Chinese Guideline for the Management of Polypoidal Choroidal Vasculopathy (2022) [10]Type 2 choroidal neovascularisation in polypoidal choroidal vasculopathy: a retrospective case series.