机构:[1]Clinical Medicine of“5+3”program, School of Basic Medical Science, Capital Medical University, Beijing, China.[2]Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University, Beijing, China.首都医科大学附属安贞医院[3]Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University,Beijing, China.[4]Eight Program of Clinical Medicine, Peking University People’s Hospital, Beijing, China.[5]Morphological Experiment Center, School of Basic Medical Sciences, Capital Medical University, Beijing, China.[6]Department of Dermatology, Beijing Tongren Hospital, Capital Medical University, Beijing,China.临床科室皮肤性病科首都医科大学附属北京同仁医院首都医科大学附属同仁医院
With the incidence of hypertension increasing worldwide, more and more the mechanisms of hypertension from the perspective of immunity have found. Intestinal microbiota as well as its metabolites relationship with hypertension has attracted great attention from both clinicians and investigators. However, the associations of hypertension with lesions of a large number of immune factors including IL-17, MCP-1, IL-6, TGF-beta, IL-10 and others have not been fully characterized. In this review, after introducing the immune factors as the most potent anti/pro-hypertension agents known, we provide detailed descriptions of the IL-17 involved in the pathology of hypertension, pointing out the underlying mechanisms and suggesting the clinical indications.
基金:
National Natural Science Foundation of China [821714056, 81373671JD]
第一作者机构:[1]Clinical Medicine of“5+3”program, School of Basic Medical Science, Capital Medical University, Beijing, China.[2]Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University, Beijing, China.
共同第一作者:
通讯作者:
推荐引用方式(GB/T 7714):
Yang Ze-Jun,Wang Tian-Tian,Wang Bo-Ya,et al.Deeper insight into the role of IL-17 in the relationship beween hypertension and intestinal physiology[J].JOURNAL OF INFLAMMATION-LONDON.2022,19(1):doi:10.1186/s12950-022-00311-0.
APA:
Yang, Ze-Jun,Wang, Tian-Tian,Wang, Bo-Ya,Gao, Han,He, Cheng-Wei...&Xu, Jing-Dong.(2022).Deeper insight into the role of IL-17 in the relationship beween hypertension and intestinal physiology.JOURNAL OF INFLAMMATION-LONDON,19,(1)
MLA:
Yang, Ze-Jun,et al."Deeper insight into the role of IL-17 in the relationship beween hypertension and intestinal physiology".JOURNAL OF INFLAMMATION-LONDON 19..1(2022)