The purpose of this study was to report the distribution of mean ocular perfusion pressure (MOPP) and its associated factors in Chinese children.We enrolled 3048 grade 1 students and 2258 grade 7 students of the Anyang Childhood Eye Study in central China. Systolic and diastolic blood pressure (SBP and DBP) were recorded with a digital automatic sphygmomanometer. Intraocular pressure (IOP) was assessed by a non-contact tonometer. MOPP was calculated as 2/3 × (DBP + 1/3[SBP - DBP]) - IOP. Risk factors for myopia were obtained through a questionnaire survey.The MOPP was 33.83 ± 6.37 mm Hg (mean ± SD) in grade 1, which was lower than 36.99 ± 6.80 mm Hg in grade 7 (P < 0.001). Compared with myopic eyes, non-myopic eyes had higher MOPP in grade 7 (37.72 ± 6.72 mm Hg versus 36.58 ± 6.57 mm Hg, P < 0.001) and in grade 1 (33.88 ± 6.29 mm Hg versus 33.12 ± 7.03 mm Hg, P = 0.12). Multivariable analysis showed that higher MOPP was associated with less myopia (P < 0.001), higher body mass index (BMI; P < 0.001), thinner central corneal thickness (P < 0.001), less time on near work (P < 0.001), and more time on sleeping (P = 0.04).MOPP was higher in children of older age, with higher BMI, less time on near work, and more time on sleeping, and was higher in eyes with less myopia.We found that MOPP might be an indicator for the detection of myopia development.
基金：
Beijing Natural Science Foundation (JQ20029), the Capital Health Research and
Development of Special (2020-2-1081), and the
National Natural Science Foundation of China
(82071000)
第一作者机构：[1]Beijing Institute of Ophthalmology,Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Ophthalmology & Visual Science Key Laboratory,Beijing,China.
共同第一作者：
通讯作者：
通讯机构：[1]Beijing Institute of Ophthalmology,Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Ophthalmology & Visual Science Key Laboratory,Beijing,China.[*1]Beijing Institute of Ophthalmology,Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Ophthalmology & Visual Sciences Key Laboratory,Beijing 100730,China
推荐引用方式(GB/T 7714)：
Bai Wei-Ling,Kang Yu-Ting,Li Shi-Ming,et al.Ocular Perfusion Pressure in 7-and 12-Year-Old Chinese Children: The Anyang Childhood Eye Study[J].TRANSLATIONAL VISION SCIENCE & TECHNOLOGY.2022,11(10):doi:10.1167/tvst.11.10.26.
APA：
Bai Wei-Ling,Kang Yu-Ting,Li Shi-Ming,Gan Jia-He,Wei Shi-Fei...&Wang Ning-Li.(2022).Ocular Perfusion Pressure in 7-and 12-Year-Old Chinese Children: The Anyang Childhood Eye Study.TRANSLATIONAL VISION SCIENCE & TECHNOLOGY,11,(10)
MLA：
Bai Wei-Ling,et al."Ocular Perfusion Pressure in 7-and 12-Year-Old Chinese Children: The Anyang Childhood Eye Study".TRANSLATIONAL VISION SCIENCE & TECHNOLOGY 11..10(2022)
