机构:[1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University首都医科大学附属北京同仁医院首都医科大学附属同仁医院[2]Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing, China首都医科大学附属同仁医院[3]Industrial Engineering and Operations Research, University of California, Berkeley, USA[4]Beijing Institute of Ophthalmology, Beijing, China研究所眼科研究所首都医科大学附属北京同仁医院首都医科大学附属同仁医院
Introduction: Acute acquired concomitant esotropia (AACE) has been increased dramatically in myopia. To clarify whether fusional vergence dysfunctions exist in AACE with myopia, and to explore the relationship between fusional vergence and myopia in AACEMethods: A prospective clinical study. Adult AACE patients as well as controls (aged >= 18 years) both with myopia were prospectively recruited from October 2016 to August 2021. Refractive error and fusional divergence and convergence amplitude at distance were measured, as determined with a comprehensive refractor. The main outcome measures were the real value of the fusional divergence amplitude (calculated by subtracting the break point value from the angle of deviation) and the real value of the fusional convergence amplitude (calculated by subtracting the angle of deviation from the break point value). Two-sided p value of less than 0.05 was considered to indicate statistical significance.Results: Fusional vergence consisting of fusional divergence and fusional convergence in patients with AACE of adulthood were different from the controls (p<0.001), with fusional convergence decreased and fusional divergence increased. In the linear regression analysis, spherical equivalents were significantly negatively correlated with fusional convergence (right eyes, p<0.001; left eyes, p<0.001) in patients with AACE of adulthood but not in controls. There was a significant difference in fusional convergence amplitude among different degrees of spherical equivalents (p<0.001).Conclusions: Fusional vergence dysfunction exist in AACE of adulthood, which may be attributed to self-adaptation based on concomitant esotropia to maintain fusion in AACE. Fusional convergence was associated with degrees of myopia, implying the adaption would be weakened as the degree of myopia becomes serious.
基金:
National Natural Science Foundation of China [82101174, 82070998]; Capital Research Project of Clinical Diagnosis and Treatment Technology and Translational Application, Beijing Municipal Science & Technology Commission [Z201100005520044]; "Yangfan" clinical technology innovation project, Beijing Municipal Administration of Hospitals [XMLX202103]
第一作者机构:[1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University
共同第一作者:
通讯作者:
通讯机构:[1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University[*1]No. 1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing 100730, China
推荐引用方式(GB/T 7714):
Zhao Shiqiang,Hao Jie,Liu Jiawen,et al.Fusional vergence dysfunctions in acute acquired concomitant esotropia of adulthood with myopia[J].OPHTHALMIC RESEARCH.2023,66(1):320-327.doi:10.1159/000527884.
APA:
Zhao, Shiqiang,Hao, Jie,Liu, Jiawen,Cao, Kai&Fu, Jing.(2023).Fusional vergence dysfunctions in acute acquired concomitant esotropia of adulthood with myopia.OPHTHALMIC RESEARCH,66,(1)
MLA:
Zhao, Shiqiang,et al."Fusional vergence dysfunctions in acute acquired concomitant esotropia of adulthood with myopia".OPHTHALMIC RESEARCH 66..1(2023):320-327