机构:[1]Clinical & Epidemiological Eye Research Center, Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China[2]Glaucoma Institute, Wenzhou Medical University, Wenzhou, Zhejiang, China[3]Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China[4]Handan Eye Hospital, Handan, China[5]Centre for Public Health, Queen’s University, Belfast, United Kingdom[6]Orbis International, New York, New York, United States[7]Glaucoma Center of Excellence, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States[8]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University ,Beijing Ophthalmology & Visual Science Key Lab, Beijing, China首都医科大学附属北京同仁医院首都医科大学附属同仁医院
The purpose of this study was to determine the prevalence of myopia among patients with primary angle closure disease (PACD) in rural China and their ocular biometric characteristics.Study subjects were recruited from the Handan Eye Study. A/B-mode scan (Cine Scan, Quantel Medical, Cedex, France) was used to measure the axial length, anterior chamber depth (ACD), and lens thickness (LT). PACD was defined as the anterior chamber angle being considered closed when 180 degrees or more of the posterior pigmented trabecular meshwork were not visible on the gonioscopy. Myopia was defined as a spherical equivalent (SE) refractive error ≤-0.5 diopter (D). Persons who did not meet PACD definition were classified as the open-angle (OA) group.The overall prevalence of myopia in persons with PACD was 13.7% (11.6% in primary angle closure suspect [PACS], 21.6% in primary angle closure [PAC], 62.5% in primary angle closure glaucoma [PACG]). The age-specific prevalence of myopia in PACD eyes was 41.7% at 30 to 39 years old, 12.3% at 40 to 49 years old, 8.7% at 50 to 59 years old, 10.7% at 60 to 69 years old, and 31.7% at age 70 years and over. PACD had shorter AL (22.2 ± 0.8 vs. 22.9 ± 0.9 mm, P < 0.001), shallower ACD (2.3 ± 0.3 vs. 2.8 ± 0.4 mm, P < 0.001), and greater LT (5.0 ± 0.5 vs. 4.7 ± 0.5 mm, P < 0.001). PACD had even thicker lenses and deeper ACD with age than those with OA (all P ≤ 0.025) from 30 years to 70 years of age and over.Myopia was common among persons with PACD who were less than 40 years of age in this rural Chinese population, and over half of those with PACG were myopic.
基金:
Supported by the National Basic Research Program of China
(973 Program) Grant 2007CB512201 from Ministry of Science
&Technology of the People’s Republic of China; program of
Health Policy for Blindness Prevention from Ministry of Health
the People’s Republic of China; Key Technologies R&D Program
(No. 2006–10903) from the Bureau of Science and Technology of Handan city, Hebei Province, China; Yuanbo Liang was
supported by Zhejiang Health Innovative Talents Project (No.
2016025), and Congdon is funded by the Ulverscroft Foundation (UK). The sponsor or funding organization had no role in
the design or conduct of this research
第一作者机构:[1]Clinical & Epidemiological Eye Research Center, Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China[2]Glaucoma Institute, Wenzhou Medical University, Wenzhou, Zhejiang, China
共同第一作者:
通讯作者:
通讯机构:[8]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University ,Beijing Ophthalmology & Visual Science Key Lab, Beijing, China[*1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, Beijing, China
推荐引用方式(GB/T 7714):
Liang Yuanbo,Shen Ruyue,Zhou Weihe,et al.Prevalence and Ocular Biometric Characteristics of Myopia in Primary Angle Closure Disease in Rural China: The Handan Eye Study[J].INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE.2022,63(12):19.doi:10.1167/iovs.63.12.19.
APA:
Liang Yuanbo,Shen Ruyue,Zhou Weihe,Fan Sujie,Chan Poemen P...&Wang Ningli.(2022).Prevalence and Ocular Biometric Characteristics of Myopia in Primary Angle Closure Disease in Rural China: The Handan Eye Study.INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,63,(12)
MLA:
Liang Yuanbo,et al."Prevalence and Ocular Biometric Characteristics of Myopia in Primary Angle Closure Disease in Rural China: The Handan Eye Study".INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 63..12(2022):19