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Principle and progress of radical treatment for locally advanced esophageal squamous cell carcinoma

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机构: [1]Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China. [2]Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China. [3]Shanghai Clinical Research Center for Radiation Oncology Shanghai Key Laboratory of Radiation Oncology, Shanghai 200032, China. [4]Department of Orthopedics, Tongren Hospital, School of Medicine Shanghai Jiao Tong University, Shanghai 200336, China. [5]Department of Oncology, The Second People's Hospital of Kashgar, Kashgar 844000, Xinjiang Uygur Autonomous Region, China
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关键词: Esophageal squamous cell carcinoma Radical radiotherapy and chemotherapy Involving field irradiation Chemoradiotherapy Radical treatment

摘要:
Esophageal squamous cell carcinoma is one of the most common malignant tumors in the digestive system in China and the world. Most patients are diagnosed as locally advanced or advanced stage. Concurrent chemoradiotherapy is the standard treatment for locally advanced esophageal squamous cell carcinoma. This study intends to summarize the evidence-based medical evidence of the treatment principle of locally advanced esophageal squamous cell carcinoma, the selection of radiotherapy dose, the outline of radiotherapy target and the selection of chemotherapy scheme. As a result, the effect of radiotherapy and chemotherapy is equivalent to that of surgery for the radical treatment of esophageal squamous cell carcinoma. In the era of immunization, it is recommended to use involved field irradiation. Fluorouracil plus cisplatin regimen is the standard chemotherapy regimen. FOLFOX regimen and paclitaxel plus fluorouracil regimen are optional concurrent chemotherapy regimens. The toxic and side effects of different chemotherapy regimens are different, which can be selected according to the actual situation of patients.©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

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出版当年[2021]版:
大类 | 4 区 医学
小类 | 4 区 医学:内科
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 医学:内科
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出版当年[2020]版:
Q3 MEDICINE, GENERAL & INTERNAL
最新[2023]版:
Q3 MEDICINE, GENERAL & INTERNAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2020版] 出版当年五年平均 出版前一年[2019版] 出版后一年[2021版]

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第一作者机构: [1]Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China. [2]Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China. [3]Shanghai Clinical Research Center for Radiation Oncology Shanghai Key Laboratory of Radiation Oncology, Shanghai 200032, China.
通讯作者:
通讯机构: [1]Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China. [2]Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China. [3]Shanghai Clinical Research Center for Radiation Oncology Shanghai Key Laboratory of Radiation Oncology, Shanghai 200032, China. [*1]Department of Radiation Oncology, Fudan University Shanghai Cancer Center, No. 270 Dongan Road, Xuhui, Shanghai 200032, China
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