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A rare lumpy inflammatory lesion of the orbit: a unique case report

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机构: [1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China. [2]Pathology Department, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China
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关键词: Eosinophilic angiocentric fibrosis IgG4-related disease Histopathological examination Diagnosis Case report

摘要:
Eosinophilic angiocentric fibrosis (EAF) is a rare inflammatory lesion, especially in orbit. EAF is believed to be related to IgG4-related disease (IgG4-RD), but the clinical manifestations of systemic involvement are relatively rare and easy to be confused with tumors or other inflammatory diseases. Histopathological examination is the most important way of its diagnosis and differentiation.We presented a 55-year-old female patient presented with recurrent swelling of the right lower eyelid for more than 2 months. The pathological diagnosis was EAF. Positive immunostaining for IgG, CD34, κ, and λ, while negative immunostaining for IgG4.Complete surgical resection is the preferred treatment, histopathological examination is the main diagnostic standard.© 2023. The Author(s).

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出版当年[2022]版:
大类 | 4 区 医学
小类 | 3 区 病理学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 病理学
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出版当年[2021]版:
Q3 PATHOLOGY
最新[2023]版:
Q2 PATHOLOGY

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第一作者机构: [1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
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