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Numerical simulation of mechanical properties of epiretinal membrane peeling

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机构: [1]School of Energy Power and Mechanical Engineering, North China Electric Power University, Beijing, China. [2]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China. [3]School of Mechanical Engineering and Automation, Beihang University, Beijing, China. [4]College of Automation and College of Artificial Intelligence, Nanjing University of Posts and Telecommunications, Nanjing, China.
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关键词: Epiretinal membrane retina peeling force finite element method

摘要:
An epiretinal membrane (ERM) is a fibrocellular proliferation on the inner surface of the retina causing blurred and distorted central vision. Surgery is the only effective method for ERM removal. This paper investigated the mechanical properties of ERM peeling using the finite element (FE) method. A FE model of ERM formation on the retina surface was constructed. The failure criterion was applied to the attachment pegs to represent the adhesive force between the ERM and retina. The simulation results were consistent with the experimental data in published research. The maximum peeling force was 4.1 mN at a peeling velocity of 2 mm/s and an angle of 30°. The peeling force was minimum at the peeling angle of 45° and increased with the increase in peeling velocity and Young's modulus of the membrane. The outcome of this paper can improve the safety and efficiency of ERM removal.

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出版当年[2023]版:
大类 | 4 区 医学
小类 | 4 区 计算机:跨学科应用 4 区 工程:生物医学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 计算机:跨学科应用 4 区 工程:生物医学
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出版当年[2022]版:
Q4 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Q4 ENGINEERING, BIOMEDICAL
最新[2023]版:
Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Q3 ENGINEERING, BIOMEDICAL

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第一作者机构: [1]School of Energy Power and Mechanical Engineering, North China Electric Power University, Beijing, China.
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