资源类型：
期刊
WOS体系：
Review
Pubmed体系：
Journal Article;Review
收录情况：
◇ SCIE
文章类型：
论著
机构：
[1]Beijing Tongren Hospital, Capital Medical University, Beijing, China
首都医科大学附属北京同仁医院
首都医科大学附属同仁医院
[2]Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China
首都医科大学附属同仁医院
ISSN：
0275-5408
关键词：
epidemiology
genetics
myopia
摘要：
Myopia is a health issue that has attracted global attention due to its high prevalence and vision-threatening complications. It is well known that the onset and progression of myopia are related to both genetic and environmental factors: more than 450 common genetic loci have been found to be associated with myopia, while near work and outdoor time are the main environmental risk factors. As for many complex traits, gene-environment interactions are implicated in myopia development. To date, several genetic loci have been found to interact with near work or educational level. Gene-environment interaction research on myopia could yield models that provide more accurate risk predictions, thus improving targeted treatments and preventive strategies. Additionally, such investigations might have the potential to reveal novel genetic information. In this review, we summarised the findings in this field and proposed some topics for future investigations.© 2023 College of Optometrists.
基金：
Beijing Science Foundation for Distinguished
Young Scholars, Grant/Award Number:
JQ20029; Capital health research and
development of special grant, Grant/Award
Number: 2020-2-
1081;
National Natural
Science Foundation of China, Grant/Award
Number: 82071000 and 82201244; Beijing
Hospitals Authority Innovation Studio of
Young Staff Funding Support, Grant/Award
Number: 202106
被引次数：
7
WOS：
WOS:001033918500001
PubmedID：
37486033
中科院(CAS)分区：
出版当年[2022]版：
大类
|
2 区
医学
小类
|
2 区
眼科学
最新[2025]版：
大类
|
2 区
医学
小类
|
2 区
眼科学
JCR分区：
出版当年[2021]版：
Q2
OPHTHALMOLOGY
最新[2023]版：
Q2
OPHTHALMOLOGY
影响因子：
2.8
最新[2023版]
3.5
最新五年平均
3.992
出版当年[2021版]
3.946
出版当年五年平均
3.117
出版前一年[2020版]
2.9
出版后一年[2022版]
第一作者：
He Xi
第一作者机构：
[1]Beijing Tongren Hospital, Capital Medical University, Beijing, China
[2]Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China
通讯作者：
Li Shi-Ming
通讯机构：
[1]Beijing Tongren Hospital, Capital Medical University, Beijing, China
[2]Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China
[*1]Beijing Tongren Eye Centre, Beijing Tongren Hospital, Capital Medical University, Beijing, China and Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China.
推荐引用方式(GB/T 7714)：
He Xi,Li Shi-Ming.Gene-environment interaction in myopia[J].OPHTHALMIC AND PHYSIOLOGICAL OPTICS.2023,43(6):1438-1448.doi:10.1111/opo.13206.
APA：
He Xi&Li Shi-Ming.(2023).Gene-environment interaction in myopia.OPHTHALMIC AND PHYSIOLOGICAL OPTICS,43,(6)
MLA：
He Xi,et al."Gene-environment interaction in myopia".OPHTHALMIC AND PHYSIOLOGICAL OPTICS 43..6(2023):1438-1448
