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Optical Coherence Tomography: Imaging Visual System Structures in Mice

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机构： [1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China. [2]Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

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关键词： Optical coherence tomography Noninvasive ocular imaging In vivo imaging Retinal thickness Nerve fiber layer thickness

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Optical coherence tomography (OCT) enables micron-scale resolution of structural anatomy, thereby making OCT a valuable tool for addressing ophthalmologic and neurologic inquiries. Although the murine eye and its structures are very small and offers challenges for OCT imaging, OCT can be used to monitor retinal layer thickness in healthy and diseased retinas in murine lines in vivo longitudinally. Thus, OCT can provide insights into disease severity and treatment efficacy. This chapter describes the use of OCT as a powerful non-invasive imaging technology for high-resolution retinal imaging and retinal thickness quantification in rodents.© 2023. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

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第一作者机构： [1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China. [2]Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

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