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Growth differentiation factor-15 may be a novel biomarker in pancreatic cancer: A review

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收录情况： ◇ SCIE

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机构： [1]Shanghai Jiaotong University School of Medicine affiliated Tongren Hospital, Shanghai, China.

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关键词： CA199 GDF-15 MIC-1 pancreatic cancer tumor marker

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Pancreatic cancer is a highly malignant and invasive gastrointestinal tumor that is often diagnosed at an advanced stage with a poor prognosis and high mortality. Currently, carbohydrate antigen199(CA199) is the only biomarker approved by the FDA for the diagnosis of pancreatic cancer, but it has great limitations. Growth differentiation factor-15 (GDF-15) is expected to be a novel biomarker for the diagnosis, efficacy prediction, and prognosis assessment of pancreatic cancer patients. In this paper, we searched the keywords GDF-15, macrophage inhibitory cytokine-1 (MIC-1), CA199, pancreatic cancer, and tumor markers in PubMed and Web of Science, searched related articles, and read and analyzed the retrieved papers. Finally, we systematically described the characteristics, mechanism of action, and clinical value of GDF-15, aiming to provide help for the detection and treatment of pancreatic cancer.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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出版当年[2023]版：

大类 | 4 区医学

小类 | 4 区医学：内科

最新[2025]版：

大类 | 4 区医学

小类 | 4 区医学：内科

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出版当年[2022]版：

Q3 MEDICINE, GENERAL & INTERNAL

最新[2023]版：

Q2 MEDICINE, GENERAL & INTERNAL

影响因子： 1.4 最新[2023版] 1.6 最新五年平均 1.6 出版当年[2022版] 1.9 出版当年五年平均 1.817 出版前一年[2021版] 1.4 出版后一年[2023版]

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第一作者机构： [1]Shanghai Jiaotong University School of Medicine affiliated Tongren Hospital, Shanghai, China.

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