Pancreatic cancer (PC) is an aggressive malignancy with a high mortality rate and poor prognosis. Numerous investigations have shown that microRNA (miRNA) plays a vital role in PC. Thousands of miRNAs have been screened in PC and altered miRNAs, including circulating miRNAs, are associated with PC proliferation, apoptosis, metastasis, chemosensitivity, and radiosensitivity. Several studies have shown that miRNAs can act as potential diagnostic and prognostic markers. The present review focuses on recent advances regarding the roles of miRNAs in PC and their practical value.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81302332]
第一作者机构：[1]Shanghai Jiao Tong Univ, Sch Med, Tongren Hosp, Dept Intervent Radiol, Shanghai 200050, Peoples R China
通讯作者：
通讯机构：[1]Shanghai Jiao Tong Univ, Sch Med, Tongren Hosp, Dept Intervent Radiol, Shanghai 200050, Peoples R China[*1]Department of Interventional Radiology, Tongren Hospital, Shanghai Jiaotong University School of Medicine786 Yuyuan Road, Shanghai 200050, P. R. China
推荐引用方式(GB/T 7714)：
Liu Bingyan,Zhang Xiaoping,Mao Aiwu.Critical role of miRNAs in pancreatic cancer[J].FRONTIERS IN BIOSCIENCE-LANDMARK.2015,20:1017-1028.doi:10.2741/4354.
APA：
Liu, Bingyan,Zhang, Xiaoping&Mao, Aiwu.(2015).Critical role of miRNAs in pancreatic cancer.FRONTIERS IN BIOSCIENCE-LANDMARK,20,
MLA：
Liu, Bingyan,et al."Critical role of miRNAs in pancreatic cancer".FRONTIERS IN BIOSCIENCE-LANDMARK 20.(2015):1017-1028
