机构:[1]Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China临床科室变态反应科首都医科大学附属北京同仁医院首都医科大学附属同仁医院[2]Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China临床科室耳鼻咽喉-头颈外科首都医科大学附属北京同仁医院首都医科大学附属同仁医院[3]Beijing Laboratory of Allergic Diseases, Beijing Institute of Otolaryngology, Beijing, China研究所耳鼻咽喉科研究所首都医科大学附属北京同仁医院首都医科大学附属同仁医院
Chronic rhinitis (CR) represents a prevalent, persistent inflammatory condition of the nasal mucosa, substantially impacting patients' quality of life. Despite standard pharmacotherapy, many patients with refractory symptoms do not achieve adequate relief, highlighting the need for alternative interventions such as nasal neurectomy.Literature was reviewed on the PubMed, EMBASE, and Web of Science databases published from March 1961 to April 2025. Our review discusses the underlying mechanisms, surgical techniques, and clinical outcomes of different nasal neurectomy approaches, including vidian neurectomy, vidian-branch neurectomy, and anterior ethmoidal neurectomy, as well as recent advancements in endoscopic and minimally invasive methods.Nasal neurectomy presents a promising alternative for managing refractory CR by directly targeting the neuro-immune pathways that drive symptoms. Understanding the mechanisms, techniques, and clinical outcomes in nasal neurectomy will not only advance our insight into CR pathophysiology but also guide the development of refined, patient-specific surgical strategies for optimal outcomes.
基金:
national key R&D program of
China [2022YFC2504100], Natural Science Foundation of China [82471132
and 82071022] and Beijing Hospitals Authority Clinical Medicine
Development of Special Funding [ZLRK202303].
第一作者机构:[1]Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China[2]Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China[3]Beijing Laboratory of Allergic Diseases, Beijing Institute of Otolaryngology, Beijing, China
共同第一作者:
通讯作者:
通讯机构:[1]Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China[2]Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China[3]Beijing Laboratory of Allergic Diseases, Beijing Institute of Otolaryngology, Beijing, China
推荐引用方式(GB/T 7714):
Zhang Zengxiao,Wei Hongzheng,Wang Chengshuo,et al.Innovative surgical approaches for chronic rhinitis: nasal neurectomy mechanisms, techniques, and clinical outcomes[J].Expert Review Of Clinical Immunology.2025,21(5):567-576.doi:10.1080/1744666X.2025.2500610.
APA:
Zhang Zengxiao,Wei Hongzheng,Wang Chengshuo,Zhang Luo&Zhang Yuan.(2025).Innovative surgical approaches for chronic rhinitis: nasal neurectomy mechanisms, techniques, and clinical outcomes.Expert Review Of Clinical Immunology,21,(5)
MLA:
Zhang Zengxiao,et al."Innovative surgical approaches for chronic rhinitis: nasal neurectomy mechanisms, techniques, and clinical outcomes".Expert Review Of Clinical Immunology 21..5(2025):567-576