机构:[1]Department of Pulmonary and Critical Care Medicine,Center of RespiratoryMedicine,China-Japan FriendshipHospital, Beijing,China[2]the Institute of Clinical Medical Sciences, China-Japan Friendship Hospital,Beijing, China[3]National Clinical Research Center for Respiratory Diseases, Beijing,China[4]the Graduate School of Peking UnionMedical College,Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China[5]Beijing University of Chinese Medicine,Beijing, China[6]Peking University Health Science Center, Beijing, China[7]Department of Pulmonary and Critical Care Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China重庆医科大学附属第一医院[8]Department of Respiratory Medicine, First Affiliated Hospital of Dalian Medical University, Liaoning Province,China大连医科大学附属第一医院[9]Department of Pulmonary and Critical Medicine,West China Hospital, Sichuan University, Sichuan Province, China四川大学华西医院[10]Department of Pulmonary and Critical Care Medicine, Beijing Hospital, Beijing, China[11]Department of Pulmonary and Critical Care Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing Institute of RespiratoryMedicine, and the Department of Respiratory Medicine, Capital Medical University, Beijing, China.北京朝阳医院
BACKGROUND: VTE has emerged as a major public health problem. However, data on VTE burden in China are seldom reported. METHODS: This study collected data on patients with a principal diagnosis of VTE, pulmonary embolism (PE), or DVT by using the International Classification of Diseases, 10th Revision, from 90 hospitals across China. The trends in hospitalization rates, mortality, length of stay (LOS), and comorbidities from 2007 to 2016 were analyzed. RESULTS: In total, 105,723 patients with VTE were identified. For patients with VTE, the age-and sex-adjusted hospitalization rate increased from 3.2 to 17.5 per 100,000 population, and in-hospital mortality decreased from 4.7% to 2.1% (P < .001). The mean LOS declined from 14 to 11 days (P < .001). In addition, the data in 2016 showed that the hospitalization rate of VTE was higher in elderly male patients (male patients vs female patients, 155.3 vs 125.4 per 100,000 population in patients aged >= 85 years; P < .001) and in northern China (north vs south, 18.4 vs 13.4 per 100,000 population; P < .001). Higher mortality rates were found in patients with cancer and Charlson Comorbidity Index scores > 2. Similar trends were also observed in patients with PE and those with DVT. The hospitalization rate in China was much lower than that of the United States or selected sites in Canada and Europe, the LOS was much longer, and the in-hospital mortality rates were similar. CONCLUSIONS: The hospitalization rates of VTE increased steadily, and the mortality declined. This study provides important information on the disease burden of VTE in China.
基金:
This study was supported by the Fund provided by
The National Key Research and Development Program of China [No.
2016YFC0905600], China Key Research Projects of National Five-year
Development Plan [No. 2006BAI01A06 and 2011BA11B17],Beijing Natural Science Foundation [No. 7152062], and National
Natural Science Foundation of China [No. 81570049].
第一作者机构:[1]Department of Pulmonary and Critical Care Medicine,Center of RespiratoryMedicine,China-Japan FriendshipHospital, Beijing,China[3]National Clinical Research Center for Respiratory Diseases, Beijing,China[4]the Graduate School of Peking UnionMedical College,Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China
通讯作者:
通讯机构:[1]Department of Pulmonary and Critical Care Medicine,Center of RespiratoryMedicine,China-Japan FriendshipHospital, Beijing,China[3]National Clinical Research Center for Respiratory Diseases, Beijing,China[4]the Graduate School of Peking UnionMedical College,Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China[*1]Department of Pulmonary and Critical Care Medicine,Center of Respiratory Medicine, China-Japan Friendship Hospital,National Clinical Research Center for Respiratory Diseases,Chinese Academy of Medical Sciences, Peking Union Medical, No. 2, East Yinghua Rd, Chaoyang District, Beijing, China, 100029
推荐引用方式(GB/T 7714):
Zhu Zhang,Jieping Lei,Xiang Shao,et al.Trends in Hospitalization and In-Hospital Mortality From VTE, 2007 to 2016, in Chin[J].CHEST.2019,155(2):342-353.doi:10.1016/j.chest.2018.10.040.
APA:
Zhu Zhang,Jieping Lei,Xiang Shao,Fen Dong,Jing Wang...&Chen Wang.(2019).Trends in Hospitalization and In-Hospital Mortality From VTE, 2007 to 2016, in Chin.CHEST,155,(2)
MLA:
Zhu Zhang,et al."Trends in Hospitalization and In-Hospital Mortality From VTE, 2007 to 2016, in Chin".CHEST 155..2(2019):342-353