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Facile synthesis of yolk-shell structured Fe3O4@C-Au nanoparticles for thermotherapic application

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机构: [1]Accurate Medical Center, Taizhou Central Hospital, Taizhou, Zhejiang 318000, PR China [2]State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, PR China [3]Institute for Intestinal Diseases, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200072, PR China [4]Tong Ren Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200331, PR China [5]Department of Vascular Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital of Shanghai, Shanghai 200233, PR China
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关键词: Biomaterials Nanoparticles Yolk-shell Small size Fe3O4@C-Au Large inner space Thermotherapy

摘要:
Yolk-shell nanostructures haves promising applications in cancer therapy due to their great potential for multi-functions. However, the control over its structure and morphology still remains a big challenge. Herein, yolk-shell Fe3O4@C-Au composite nanostructure has been successfully synthesized with magnetic Fe3O4 nanoparticles encapsulated in hollow carbon shells and Au nanoparticles well dispersed. The yolk-shell structure has a uniform size of similar to 80 nm and a high surface area of 325.13 m(2)/g. The Fe3O4 and Au nanoparticles are 10 and 3 nm, respectively. The as-prepared Fe3O4@C-Au showed good biocompatibility during endocytosis process. The Fe3O4@C-Au suspension (150 mu g/ml) shows efficient photothermal conversion effect and effectively damage 4T1 cells. The composite nanostructure Fe3O4@C-Au show promising applications in cancer diagnosis and therapy. (C) 2019 Elsevier B.V. All rights reserved.

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出版当年[2019]版:
大类 | 3 区 工程技术
小类 | 3 区 材料科学:综合 3 区 物理:应用
最新[2023]版:
大类 | 4 区 材料科学
小类 | 4 区 材料科学:综合 4 区 物理:应用
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出版当年[2018]版:
Q2 PHYSICS, APPLIED Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY
最新[2023]版:
Q2 PHYSICS, APPLIED Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

影响因子: 最新[2023版] 最新五年平均 出版当年[2018版] 出版当年五年平均 出版前一年[2017版] 出版后一年[2019版]

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第一作者机构: [1]Accurate Medical Center, Taizhou Central Hospital, Taizhou, Zhejiang 318000, PR China [2]State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, PR China
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通讯机构: [1]Accurate Medical Center, Taizhou Central Hospital, Taizhou, Zhejiang 318000, PR China [2]State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, PR China [3]Institute for Intestinal Diseases, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200072, PR China [*1]Accurate Medical Center, Taizhou Central Hospital, Taizhou, Zhejiang 318000, PR China [*2]State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, PR China
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