机构:[1]Accurate Medical Center, Taizhou Central Hospital, Taizhou, Zhejiang 318000, PR China[2]State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, PR China[3]Institute for Intestinal Diseases, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200072, PR China[4]Tong Ren Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200331, PR China[5]Department of Vascular Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital of Shanghai, Shanghai 200233, PR China
Yolk-shell nanostructures haves promising applications in cancer therapy due to their great potential for multi-functions. However, the control over its structure and morphology still remains a big challenge. Herein, yolk-shell Fe3O4@C-Au composite nanostructure has been successfully synthesized with magnetic Fe3O4 nanoparticles encapsulated in hollow carbon shells and Au nanoparticles well dispersed. The yolk-shell structure has a uniform size of similar to 80 nm and a high surface area of 325.13 m(2)/g. The Fe3O4 and Au nanoparticles are 10 and 3 nm, respectively. The as-prepared Fe3O4@C-Au showed good biocompatibility during endocytosis process. The Fe3O4@C-Au suspension (150 mu g/ml) shows efficient photothermal conversion effect and effectively damage 4T1 cells. The composite nanostructure Fe3O4@C-Au show promising applications in cancer diagnosis and therapy. (C) 2019 Elsevier B.V. All rights reserved.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [51672174]; Material Genome Initiative Project Foundation of Science and Technology Commission of Shanghai Municipality [16DZ2260602]; Medicine-Engineering Cross Foundation of Shanghai Jiao Tong University [YG2015MS63]
第一作者机构:[1]Accurate Medical Center, Taizhou Central Hospital, Taizhou, Zhejiang 318000, PR China[2]State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, PR China
共同第一作者:
通讯作者:
通讯机构:[1]Accurate Medical Center, Taizhou Central Hospital, Taizhou, Zhejiang 318000, PR China[2]State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, PR China[3]Institute for Intestinal Diseases, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200072, PR China[*1]Accurate Medical Center, Taizhou Central Hospital, Taizhou, Zhejiang 318000, PR China[*2]State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, PR China
推荐引用方式(GB/T 7714):
Feng Xiaoqian,Xu Wei,Zhang Chi,et al.Facile synthesis of yolk-shell structured Fe3O4@C-Au nanoparticles for thermotherapic application[J].MATERIALS LETTERS.2020,258:doi:10.1016/j.matlet.2019.126809.
APA:
Feng, Xiaoqian,Xu, Wei,Zhang, Chi,Tan, Shuo,Zhang, Jian...&Zhang, Yang.(2020).Facile synthesis of yolk-shell structured Fe3O4@C-Au nanoparticles for thermotherapic application.MATERIALS LETTERS,258,
MLA:
Feng, Xiaoqian,et al."Facile synthesis of yolk-shell structured Fe3O4@C-Au nanoparticles for thermotherapic application".MATERIALS LETTERS 258.(2020)