机构：[1]Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China首都医科大学附属北京同仁医院临床科室耳鼻咽喉-头颈外科[2]Department of Otolaryngology, Head and Neck Surgery, Beijing Ditan Hospital, Capital Medical University, Beijing, China[3]Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China临床科室变态反应科首都医科大学附属北京同仁医院首都医科大学附属同仁医院[4]Department of Otolaryngology, Head and Neck Surgery, The Second Affiliated Hospital of Baotou Capital Medical University, Inner Mongolia, China[5]Department of Otolaryngology, Head and Neck Surgery, The First Affiliated Hospital of Dalian Medical University, Liaoning, China大连医科大学附属第一医院[6]Department of Otolaryngology, Head and Neck Surgery, The First Affiliated Hospital of JiNan University, Guangdong, China[7]Department of Otolaryngology, Head and Neck Surgery, Weifang People's Hospital, Shandong, China[8]Key Laboratory of Otolaryngology, Head and Neck Surgery, Ministry of Education, Beijing Institute of Otolaryngology, Beijing, China研究所耳鼻咽喉科研究所首都医科大学附属北京同仁医院首都医科大学附属同仁医院
Background We aimed to assess the recurrence risk of sinonasal inverted papillomas (SNIPs), based on a staging system developed according to the originating site of SNIP. Methods A total of 200 patients with SNIP were enrolled, and a staging system was developed based on the originating sites and corresponding recurrence rates of tumor in the patients. In the verification phase, 675 patients with SNIPs were enrolled as above, and the originating sites of the SNIPs were confirmed by an endoscopic sinus surgery. Cluster analysis was performed to determine the stage for each SNIP. Results Overall, 608 patients completed the study. SNIP recurrence rates for stages 1-4 were 0 (n = 43), 4.0% (n = 420), 13.4% (n = 134), 36.4% (n = 11), respectively (total = 6.4%). Conclusions The origin site-based classification of SNIP may aid surgeons in selecting appropriate endoscopic surgical approaches to minimize the risk of recurrence.
基金：
National key R&D program of China, Grant/
Award Number: 2016YFC20160905200;
Changjiang scholars and innovative research team,
Grant/Award Number: IRT13082; National natural
science foundation of China, Grant/Award
Number: 81420108009, 81630023, 81400444 and
81470678; Beijing Municipal Administration of
Hospitals' Mission Plan, Grant/Award Number:
SML20150203; Beijing Municipal Administration
of Hospitals' Youth Programme, Grant/Award
Number: QML20150202; Beijing advanced
innovation center for food nutrition and human
health (Beijing Technology and Business
University), Grant/Award Number: 20181045;
Beijing Municipal Administration of Hospitals
Clinical Medicine Development of Special
Funding Support, Grant/Award Number:
XMLX201816; Capital Health Development
Foundation, Grant/Award Number: 2016-1-2052
第一作者机构：[1]Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[1]Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China[3]Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China[8]Key Laboratory of Otolaryngology, Head and Neck Surgery, Ministry of Education, Beijing Institute of Otolaryngology, Beijing, China[*1]Beijing Institute of Otolaryngology, No. 17, Hougou Hutong, DongCheng District, Beijing 100005, China.[*2]Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China.
推荐引用方式(GB/T 7714)：
Meng Yifan,Fang Gaoli,Wang Xiangdong,et al.Origin site-based staging system of sinonasal inverted papilloma for application to endoscopic sinus surgery[J].HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK.2019,41(2):440-447.doi:10.1002/hed.25435.
APA：
Meng, Yifan,Fang, Gaoli,Wang, Xiangdong,Song, Xiaohong,Wang, Kuiji...&Wang, Chengshuo.(2019).Origin site-based staging system of sinonasal inverted papilloma for application to endoscopic sinus surgery.HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK,41,(2)
MLA：
Meng, Yifan,et al."Origin site-based staging system of sinonasal inverted papilloma for application to endoscopic sinus surgery".HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK 41..2(2019):440-447
