机构:[1]Hongqiao International Institute of Medicine, Shanghai Tongren Hospital and Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China[2]Cancer Epidemiology Program, University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, USA
Cigarette smoking plays an important role in the process of lung cancer, during which DNA damage is proved to be involved. Non-coding RNAs are found to be involved in the DNA damage and repair processes induced by cigarette smoke. In the present study, we investigated the role of lncRNA LCPAT1 in DNA damage caused by CSE in Beas-2B cells. Our results indicate that LCPAT1, through RCC2 is involved in the CSE-induced DNA damage providing new insight into the lung carcinogenesis related to cigarette smoking. (C) 2018 Published by Elsevier Inc.
基金:
This work was supported by the Natural Science Foundation of Shanghai (Grant No.16ZR1418500) and SJTU Medicine-Engineering
Research Fund (Grant No.YG2016QN76).
第一作者机构:[1]Hongqiao International Institute of Medicine, Shanghai Tongren Hospital and Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
通讯作者:
推荐引用方式(GB/T 7714):
Gao Sumeng,Lin Hongyan,Yu Wang,et al.LncRNA LCPAT1 is involved in DNA damage induced by CSE[J].BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.2019,508(2):512-515.doi:10.1016/j.bbrc.2018.11.171.
APA:
Gao, Sumeng,Lin, Hongyan,Yu, Wang,Zhang, Fangfang,Wang, Ruoyang...&Qian, Biyun.(2019).LncRNA LCPAT1 is involved in DNA damage induced by CSE.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,508,(2)
MLA:
Gao, Sumeng,et al."LncRNA LCPAT1 is involved in DNA damage induced by CSE".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 508..2(2019):512-515