Primary angle closure disease (PACD), prevalent in Asian countries, is generally associated with a shallower anterior chamber, a shorter axial length, thicker lens, hyperopia, and female sex. Other physiologic factors, however, may be important, especially with regard to triggering acute primary angle closure. Thickening of the choroid has been demonstrated in untreated and treated, acute and chronic PACD eyes. Recently, there has been growing interest in studying the role of the choroid in the pathophysiology of PACD. The emergence of new imaging technology such as the enhanced depth imaging mode of spectral-domain optical coherence tomography and swept-source optical coherence tomography has contributed to understanding PACD pathologies. We summarize the functions of the choroid and choroidal changes in the pathogenesis of PACD, and discuss potential future developments. (C) 2015 Elsevier Inc. All rights reserved.
基金:
Science and Technology
Program of Guangdong Province, China (2013B020400003), and
the Science and Technology Program of Guangzhou, China
(15570001)
第一作者机构:[1]Sun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R China[*1]Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-Sen University, 54S. Xianlie Road, Guangzhou 510060, China.
通讯作者:
通讯机构:[1]Sun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R China[*1]Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-Sen University, 54S. Xianlie Road, Guangzhou 510060, China.
推荐引用方式(GB/T 7714):
Zhang Xiulan,Wang Wei,Aung Tin,et al.Choroidal physiology and primary angle closure disease[J].SURVEY OF OPHTHALMOLOGY.2015,60(6):547-556.doi:10.1016/j.survophthal.2015.06.005.
APA:
Zhang, Xiulan,Wang, Wei,Aung, Tin,Jonas, Jost B.&Wang, Ningli.(2015).Choroidal physiology and primary angle closure disease.SURVEY OF OPHTHALMOLOGY,60,(6)
MLA:
Zhang, Xiulan,et al."Choroidal physiology and primary angle closure disease".SURVEY OF OPHTHALMOLOGY 60..6(2015):547-556