The prognostic role of c-erbB-2 in gastric cancer is controversial. We conducted a meta-analysis to evaluate the relationship between c-erbB-2 expression and the prognosis of gastric cancer. We evaluated 20 published studies assessing the relationship between c-erbB-2 and gastric cancer prognosis. The Revman 5.0 software was used to perform literature retrieval, article selection, data collection, and statistical analysis. We utilized a fixed-effect model to pool hazard ratios and 95% confidence intervals from the studies. A total of 20 eligible studies including 4468 gastric cancer patients were analyzed. We were unable to demonstrate the prognostic value of c-erbB-2 for gastric cancer (hazard ratio = 1.01, 95% confidence interval = 0.87-1.16, P = 0.93). The present study indicated that c-erbB-2 expression is not a prognostic factor for gastric cancer.
第一作者机构：[1]Shanghai Jiao Tong Univ, Affiliated Tongren Hosp, Dept Surg, Shanghai 200030, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Wang Z. Q.,Sun B. J..c-erbB-2 expression and prognosis of gastric cancer: a meta-analysis[J].GENETICS AND MOLECULAR RESEARCH.2015,14(1):1782-1787.doi:10.4238/2015.March.13.5.
APA：
Wang, Z. Q.&Sun, B. J..(2015).c-erbB-2 expression and prognosis of gastric cancer: a meta-analysis.GENETICS AND MOLECULAR RESEARCH,14,(1)
MLA：
Wang, Z. Q.,et al."c-erbB-2 expression and prognosis of gastric cancer: a meta-analysis".GENETICS AND MOLECULAR RESEARCH 14..1(2015):1782-1787
